期刊
EXPERT REVIEW OF VACCINES
卷 16, 期 2, 页码 137-149出版社
TAYLOR & FRANCIS LTD
DOI: 10.1080/14760584.2017.1232167
关键词
Bronchus associated lymphoid tissue; cellular immunity; oral immunization; subunit vaccine; parenteral immunization; molecular pharming
类别
资金
- CONACYT/Mexico [INFR-2016-270028]
Introduction: Respiratory infections have an enormous, worldwide epidemiologic impact on humans and animals. Among the prophylactic measures, vaccination has the potential to neutralize this impact. New technologies for vaccine production and delivery are of importance in this field since they offer the potential to develop new immunization approaches overriding the current limitations that comprise high cost, safety issues, and limited efficacy.Areas covered: In the present review, the state of the art in developing plant-based vaccines against respiratory diseases is presented. The review was based on the analysis of current biomedical literature.Expert commentary: Preclinical and clinical evaluations of several vaccine candidates against influenza, tuberculosis, respiratory syncytial virus, pneumonia, anthrax and asthma are discussed and placed in perspective.
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