相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Targeting EZH2 in cancer
Kimberly H. Kim et al.
NATURE MEDICINE (2016)
Highly Parallel Genome-wide Expression Profiling of Individual Cells Using Nanoliter Droplets
Evan Z. Macosko et al.
CELL (2015)
Panobinostat: First Global Approval
Karly P. Garnock-Jones
DRUGS (2015)
HDAC inhibition attenuates cardiac hypertrophy by acetylation and deacetylation of target genes
Jenny Y. Y. Ooi et al.
EPIGENETICS (2015)
Single-cell ChIP-seq reveals cell subpopulations defined by chromatin state
Assaf Rotem et al.
NATURE BIOTECHNOLOGY (2015)
DOT1L inhibits SIRT1-mediated epigenetic silencing to maintain leukemic gene expression in MLL-rearranged leukemia
Chun-Wei Chen et al.
NATURE MEDICINE (2015)
ChIPmentation: fast, robust, low-input ChIP-seq for histones and transcription factors
Christian Schmidt et al.
NATURE METHODS (2015)
Computational and analytical challenges in single-cell transcriptomics
Oliver Stegle et al.
NATURE REVIEWS GENETICS (2015)
Beating the odds: BETs in disease
Chen-Yi Wang et al.
TRENDS IN BIOCHEMICAL SCIENCES (2015)
Progress of HDAC Inhibitor Panobinostat in the Treatment of Cancer
Xiaoyang Li et al.
CURRENT DRUG TARGETS (2014)
Endothelial, epithelial, and fibroblast cells exhibit specific splicing programs independently of their tissue of origin
Pierre Mallinjoud et al.
GENOME RESEARCH (2014)
Vascular histone deacetylation by pharmacological HDAC inhibition
Haloom Rafehi et al.
GENOME RESEARCH (2014)
Selective Inhibition of EZH2 by EPZ-6438 Leads to Potent Antitumor Activity in EZH2-Mutant Non-Hodgkin Lymphoma
Sarah K. Knutson et al.
MOLECULAR CANCER THERAPEUTICS (2014)
NF-κB Directs Dynamic Super Enhancer Formation in Inflammation and Atherogenesis
Jonathan D. Brown et al.
MOLECULAR CELL (2014)
The Mechanisms behind the Therapeutic Activity of BET Bromodomain Inhibition
Junwei Shi et al.
MOLECULAR CELL (2014)
Genome-wide localization of small molecules
Lars Anders et al.
NATURE BIOTECHNOLOGY (2014)
Revealing long noncoding RNA architecture and functions using domain-specific chromatin isolation by RNA purification
Jeffrey J. Quinn et al.
NATURE BIOTECHNOLOGY (2014)
Chromatin enrichment for proteomics
Georg Kustatscher et al.
NATURE PROTOCOLS (2014)
Histone deacetylases and their inhibitors in cancer, neurological diseases and immune disorders
Katrina J. Falkenberg et al.
NATURE REVIEWS DRUG DISCOVERY (2014)
Unravelling the genomic targets of small molecules using high-throughput sequencing
Raphael Rodriguez et al.
NATURE REVIEWS GENETICS (2014)
Lysine deacetylase inhibition prevents diabetes by chromatin-independent immunoregulation and β-cell protection
Dan Ploug Christensen et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
A phase II study of Givinostat in combination with hydroxycarbamide in patients with polycythaemia vera unresponsive to hydroxycarbamide monotherapy
Guido Finazzi et al.
BRITISH JOURNAL OF HAEMATOLOGY (2013)
Selective Inhibition of Tumor Oncogenes by Disruption of Super-Enhancers
Jakob Loven et al.
CELL (2013)
A double take on bivalent promoters
Philipp Voigt et al.
GENES & DEVELOPMENT (2013)
BLUEPRINT: mapping human blood cell epigenomes
Joost H. A. Martens et al.
HAEMATOLOGICA (2013)
The Proteomic Investigation of Chromatin Functional Domains Reveals Novel Synergisms among Distinct Heterochromatin Components
Monica Soldi et al.
MOLECULAR & CELLULAR PROTEOMICS (2013)
The Genotype-Tissue Expression (GTEx) project
John Lonsdale et al.
NATURE GENETICS (2013)
Chromatin proteins captured by ChIP-mass spectrometry are linked to dosage compensation in Drosophila
Charlotte I. Wang et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2013)
The Xist lncRNA Exploits Three-Dimensional Genome Architecture to Spread Across the X Chromosome
Jesse M. Engreitz et al.
SCIENCE (2013)
The HAT/HDAC interplay: Multilevel control of STAT signaling
Laura Icardi et al.
CYTOKINE & GROWTH FACTOR REVIEWS (2012)
Autoacetylation of the MYST Lysine Acetyltransferase MOF Protein
Chao Yang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
EZH2 inhibition as a therapeutic strategy for lymphoma with EZH2-activating mutations
Michael T. McCabe et al.
NATURE (2012)
An integrated encyclopedia of DNA elements in the human genome
Ian Dunham et al.
NATURE (2012)
New lysine methyltransferase drug targets in cancer
Tobias Wagner et al.
NATURE BIOTECHNOLOGY (2012)
Full-length mRNA-Seq from single-cell levels of RNA and individual circulating tumor cells
Daniel Ramskold et al.
NATURE BIOTECHNOLOGY (2012)
Function of the Active Site Lysine Autoacetylation in Tip60 Catalysis
Chao Yang et al.
PLOS ONE (2012)
ChAP-MS: A Method for Identification of Proteins and Histone Posttranslational Modifications at a Single Genomic Locus
Stephanie D. Byrum et al.
CELL REPORTS (2012)
MAPK phosphatase-1 contributes to trichostatin A inhibition of cyclooxygenase-2 expression in human umbilical vascular endothelial cells exposed to lipopolysaccharide
Ya-Fen Hsu et al.
BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS (2011)
Epigenetic Modifications Basic Mechanisms and Role in Cardiovascular Disease
Diane E. Handy et al.
CIRCULATION (2011)
Advances in Whole Genome Sequencing Technology
Jianhua Zhao et al.
CURRENT PHARMACEUTICAL BIOTECHNOLOGY (2011)
The methylation hypothesis: Do epigenetic chromatin modifications play a role in epileptogenesis?
Katja Kobow et al.
EPILEPSIA (2011)
Autoacetylation of the Histone Acetyltransferase Rtt109
Brittany N. Albaugh et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Genomic Maps of Long Noncoding RNA Occupancy Reveal Principles of RNA-Chromatin Interactions
Ci Chu et al.
MOLECULAR CELL (2011)
Panhistone deacetylase inhibitors inhibit proinflammatory signaling pathways to ameliorate interleukin-18-induced cardiac hypertrophy
Gipsy Majumdar et al.
PHYSIOLOGICAL GENOMICS (2011)
Cross-linking, ligation, and sequencing of hybrids reveals RNA-RNA interactions in yeast
Grzegorz Kudla et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
The genomic binding sites of a noncoding RNA
Matthew D. Simon et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Histone deacetylase (HDAC) inhibitors attenuate cardiac hypertrophy by suppressing autophagy
Dian J. Cao et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
A User's Guide to the Encyclopedia of DNA Elements (ENCODE)
Richard M. Myers et al.
PLOS BIOLOGY (2011)
Transcriptome-wide Identification of RNA-Binding Protein and MicroRNA Target Sites by PAR-CLIP
Markus Hafner et al.
CELL (2010)
Epigenetic regulation of development by histone lysine methylation
S. Dambacher et al.
HEREDITY (2010)
The NIH Roadmap Epigenomics Mapping Consortium
Bradley E. Bernstein et al.
NATURE BIOTECHNOLOGY (2010)
iCLIP reveals the function of hnRNP particles in splicing at individual nucleotide resolution
Julian Koenig et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2010)
Fast signals and slow marks: the dynamics of histone modifications
Teresa K. Barth et al.
TRENDS IN BIOCHEMICAL SCIENCES (2010)
Trichostatin A enhances acetylation as well as protein stability of ER alpha through induction of p300 protein
Sung-Hye Kim et al.
BREAST CANCER RESEARCH (2010)
Genome-wide Mapping of HATs and HDACs Reveals Distinct Functions in Active and Inactive Genes
Zhibin Wang et al.
CELL (2009)
Purification of Proteins Associated with Specific Genomic Loci
Jerome Dejardin et al.
CELL (2009)
Autoacetylation Regulates P/CAF Nuclear Localization
Noemi Blanco-Garcia et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Histone Deacetylase Inhibitors: Potential in Cancer Therapy
P. A. Marks et al.
JOURNAL OF CELLULAR BIOCHEMISTRY (2009)
RNA-Seq: a revolutionary tool for transcriptomics
Zhong Wang et al.
NATURE REVIEWS GENETICS (2009)
The transcriptional coactivator MAML1 regulates p300 autoacetylation and HAT activity
Magnus L. Hansson et al.
NUCLEIC ACIDS RESEARCH (2009)
Identification of protein binding sites on U3 snoRNA and pre-rRNA by UV cross-linking and high-throughput analysis of cDNAs
Sander Granneman et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Lysine Acetylation Targets Protein Complexes and Co-Regulates Major Cellular Functions
Chunaram Choudhary et al.
SCIENCE (2009)
Determination of the class and isoform selectivity of small-molecule histone deacetylase inhibitors
Nagma Khan et al.
BIOCHEMICAL JOURNAL (2008)
A Novel Proteomics Approach for the Discovery of Chromatin-associated Protein Networks
Jean-Philippe Lambert et al.
MOLECULAR & CELLULAR PROTEOMICS (2008)
Lysine acetylation: Codified crosstalk with other posttranslational modifications
Xiang-Jiao Yang et al.
MOLECULAR CELL (2008)
Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project
Ewan Birney et al.
NATURE (2007)
Dimethyl sulfoxide to vorinostat: Development of this histone deacetylase inhibitor as an anticancer drug
Paul A. Marks et al.
NATURE BIOTECHNOLOGY (2007)
RIP-Chip: the isolation and identification of mRNAs, microRNAs and protein components of ribonucleoprotein complexes from cell extracts
Jack D. Keene et al.
NATURE PROTOCOLS (2006)
CLIP: A method for identifying protein-RNA interaction sites in living cells
J Ule et al.
METHODS (2005)
Role of histone acetylation in the control of gene expression
L Verdone et al.
BIOCHEMISTRY AND CELL BIOLOGY (2005)
Genomic characterization reveals a simple histone H4 acetylation code
MF Dion et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Histones and histone modifications
CL Peterson et al.
CURRENT BIOLOGY (2004)
Lysine acetylation and the bromodomain: a new partnership for signaling
XJ Yang
BIOESSAYS (2004)
Chromatin immunoprecipitation: a tool for studying histone acetylation and transcription factor binding
VA Spencer et al.
METHODS (2003)
Immunoprecipitation of native chromatin: NChIP
LP O'Neill et al.
METHODS (2003)
Histone deacetylases (HDACs): characterization of the classical HDAC family
AJM De Ruijter et al.
BIOCHEMICAL JOURNAL (2003)
Dynamics of histone acetylation in vivo. A function for acetylation turnover?
JH Waterborg
BIOCHEMISTRY AND CELL BIOLOGY (2002)
HDAC6 is a microtubule-associated deacetylase
C Hubbert et al.
NATURE (2002)
Functional divergence between histone deacetylases in fission yeast by distinct cellular localization and in vivo specificity
P Bjerling et al.
MOLECULAR AND CELLULAR BIOLOGY (2002)
Reversible cross-linking combined with immunoprecipitation to study RNA-protein interactions in vivo
S Niranjanakumari et al.
METHODS (2002)
Control of IRF-3 activation by phosphorylation
M Yoneyama et al.
JOURNAL OF INTERFERON AND CYTOKINE RESEARCH (2002)
Valproic acid defines a novel class of HDAC inhibitors inducing differentiation of transformed cells
M Göttlicher et al.
EMBO JOURNAL (2001)
Regulation of transcription factor YY1 by acetylation and deacetylation
YL Yao et al.
MOLECULAR AND CELLULAR BIOLOGY (2001)
Transcriptional control at regulatory checkpoints by histone deacetylases: molecular connections between cancer and chromatin
PA Wade
HUMAN MOLECULAR GENETICS (2001)
Acetylation: a regulatory modification to rival phosphorylation?
T Kouzarides
EMBO JOURNAL (2000)
分享论文
