期刊
CLINICAL NUCLEAR MEDICINE
卷 47, 期 1, 页码 98-100出版社
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/RLU.0000000000003750
关键词
Ga-68-Pentixafor; Burkitt lymphoma; leukemia; F-18-FDG; PET/CT
资金
- National Natural Science Foundation of China [81971651]
- Natural Science Foundation of Fujian [2019J01454, 2020J05249]
- Fujian Provincial Health Commission Science and Technology Programme [2020GGA045, 2020QNA054]
This study highlights the potential role of Ga-68-Pentixafor PET/CT in diagnosing and treating Burkitt lymphoma, and suggests further research directions.
An 18-year-old man with newly diagnosed Burkitt lymphoma/leukemia was referred for F-18-FDG and Ga-68-Pentixafor PET/CT. Ga-68-Pentixafor PET/CT revealed similar radioactivity uptake pattern to the F-18-FDG PET/CT in superior phrenic lymph node, ascending colon, ileocecum, peritoneal, marrow, and spleen. This case highlighted that it might be interesting to further investigate the role of Ga-68-Pentixafor PET/CT imaging in staging, treatment evaluation, and especially the feasibility of CXCR4-directed radioligand therapy in Burkitt lymphoma with positive expression of CXCR4.
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