4.3 Article

Pediatric biliary disorders: Multimodality imaging evaluation with clinicopathologic correlation

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CLINICAL IMAGING
卷 75, 期 -, 页码 34-45

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ELSEVIER SCIENCE INC
DOI: 10.1016/j.clinimag.2021.01.006

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Pediatric biliary disorders; Alagille syndrome; Biliary atresia; Choledochal cyst; Primary sclerosing cholangitis; Bile leak

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This paper discusses the spectrum of pathologies affecting the pediatric biliary tree, imaging modalities used for assessment, and unique features of pediatric biliary pathologies, emphasizing the importance of understanding the imaging features of biliary pathologies for clinical management.
The spectrum of pathologies affecting the biliary tree in the pediatric population varies depending on the age of presentation. While in utero insults can result in an array of anatomic variants and congenital anomalies in newborns, diverse acquired biliary pathologies are observed in older children. These acquired pathologies display different presentations and consequences than adults. Multimodality imaging assessment of the pediatric biliary system is requisite to establishing an appropriate management plan. Awareness of the imaging features of the various biliary pathologies and conveying clinically actionable information is essential to facilitate appropriate patient management. In this paper, we will illustrate the anatomy and embryology of the pediatric biliary system. Then, we will provide an overview of the imaging modalities used to assess the biliary system. Finally, we will review the unique features of the pediatric biliary pathologies, complemented by histopathologic correlation and discussions of clinical management.

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