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注意:仅列出部分参考文献,下载原文获取全部文献信息。Proteostasis of Islet Amyloid Polypeptide: A Molecular Perspective of Risk Factors and Protective Strategies for Type II Diabetes
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CHEMICAL REVIEWS (2021)
The flanking peptides issue from the maturation of the human islet amyloid polypeptide (hIAPP) slightly modulate hIAPP-fibril formation but not hIAPP-induced cell death
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CHEMISTRY-A EUROPEAN JOURNAL (2020)
Zinc Chelator Inhibits Zinc-Induced Islet Amyloid Polypeptide Deposition and Apoptosis in INS-1 Cells
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BIOLOGICAL TRACE ELEMENT RESEARCH (2019)
Zinc boosts EGCG's hIAPP amyloid Inhibition both in solution and membrane
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BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS (2019)
A cationic polymethacrylate-copolymer acts as an agonist for β-amyloid and an antagonist for amylin fibrillation
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CHEMICAL SCIENCE (2019)
A single mutation on the human amyloid polypeptide modulates fibril growth and affects the mechanism of amyloid-induced membrane damage
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BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2018)
Effects of charge and hydrophobicity on the oligomerization of peptides derived from IAPP
Yilin Wang et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2018)
Cu and Zn coordination to amyloid peptides: From fascinating chemistry to debated pathological relevance
Elena Atrian-Blasco et al.
COORDINATION CHEMISTRY REVIEWS (2018)
Mechanistic perspective and functional activity of insulin in amylin aggregation
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CHEMICAL SCIENCE (2018)
Zinc-Induced Conformational Transitions in Human Islet Amyloid Polypeptide and Their Role in the Inhibition of Amyloidosis
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JOURNAL OF PHYSICAL CHEMISTRY B (2018)
Stabilization and structural analysis of a membrane-associated hIAPP aggregation intermediate
Diana C. Rodriguez Camargo et al.
ELIFE (2017)
Implications of peptide assemblies in amyloid diseases
Pu Chun Ke et al.
CHEMICAL SOCIETY REVIEWS (2017)
Residue specific effects of human islet polypeptide amyloid on self-assembly and on cell toxicity
Lucie Khemtemourian et al.
BIOCHIMIE (2017)
Insight into a New Binding Site of Zinc Ions in Fibrillar Amylin
Vered Wineman-Fisher et al.
ACS CHEMICAL NEUROSCIENCE (2017)
Regulation of the assembly and amyloid aggregation of murine amylin by zinc
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BIOPHYSICAL CHEMISTRY (2016)
Effect of Zn2+ ions on the assembly of amylin oligomers: insight into the molecular mechanisms
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PHYSICAL CHEMISTRY CHEMICAL PHYSICS (2016)
Promotion or Inhibition of Islet Amyloid Polypeptide Aggregation by Zinc Coordination Depends on Its Relative Concentration
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BIOCHEMISTRY (2015)
Probing the Sources of the Apparent Irreproducibility of Amyloid Formation: Drastic Changes in Kinetics and a Switch in Mechanism Due to Micelle like Oligomer Formation at Critical Concentrations of IAPP
Jeffrey R. Brender et al.
JOURNAL OF PHYSICAL CHEMISTRY B (2015)
Accurate secondary structure prediction and fold recognition for circular dichroism spectroscopy
Andras Micsonai et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
Inhibition of IAPP aggregation by insulin depends on the insulin oligomeric state regulated by zinc ion concentration
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SCIENTIFIC REPORTS (2015)
The Ability of Insulin To Inhibit the Formation of Amyloid by Pro-Islet Amyloid Polypeptide Processing Intermediates Is Significantly Reduced in the Presence of Sulfated Glycosaminoglycans
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BIOCHEMISTRY (2014)
pH Dependence of Amylin Fibrillization
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BIOCHEMISTRY (2014)
The role of copper(II) and zinc(II) in the degradation of human and murine IAPP by insulin-degrading enzyme
Francesco Bellia et al.
JOURNAL OF MASS SPECTROMETRY (2014)
Defining the Molecular Basis of Amyloid Inhibitors: Human Islet Amyloid Polypeptide-Insulin Interactions
Anna C. Susa et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2014)
Cholesterol modulates the interaction of the islet amyloid polypeptide with membranes
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MOLECULAR MEMBRANE BIOLOGY (2014)
Evaluation of membrane models and their composition for islet amyloid polypeptide-membrane aggregation
Lucie Caillon et al.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2013)
Zinc stabilization of prefibrillar oligomers of human islet amyloid polypeptide
Jeffrey R. Brender et al.
CHEMICAL COMMUNICATIONS (2013)
Membrane Disruption and Early Events in the Aggregation of the Diabetes Related Peptide IAPP from a Molecular Perspective
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ACCOUNTS OF CHEMICAL RESEARCH (2012)
Phosphatidylethanolamine Enhances Amyloid Fiber-Dependent Membrane Fragmentation
Michele F. M. Sciacca et al.
BIOCHEMISTRY (2012)
Hyperamylinemia Contributes to Cardiac Dysfunction in Obesity and Diabetes A Study in Humans and Rats
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CIRCULATION RESEARCH (2012)
Structure and membrane orientation of IAPP in its natively amidated form at physiological pH in a membrane environment
Ravi Prakash Reddy Nanga et al.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2011)
Biphasic Effects of Insulin on Islet Amyloid Polypeptide Membrane Disruption
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BIOPHYSICAL JOURNAL (2011)
Transient formation of intermediate conformational states of amyloid-β peptide revealed by heteronuclear magnetic resonance spectroscopy
Takahiro Yamaguchi et al.
FEBS LETTERS (2011)
A Two-Site Mechanism for the Inhibition of IAPP Amyloidogenesis by Zinc
Samer Salamekh et al.
JOURNAL OF MOLECULAR BIOLOGY (2011)
Low pH Acts as Inhibitor of Membrane Damage Induced by Human Islet Amyloid Polypeptide
Lucie Khemtemourian et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2011)
Selection for Nonamyloidogenic Mutants of Islet Amyloid Polypeptide (IAPP) Identifies an Extended Region for Amyloidogenicity
Ayano Fox et al.
BIOCHEMISTRY (2010)
Suppression of IAPP fibrillation at anionic lipid membranes via IAPP-derived amyloid inhibitors and insulin
Daniel Sellin et al.
BIOPHYSICAL CHEMISTRY (2010)
Role of Zinc in Human Islet Amyloid Polypeptide Aggregation
Jeffrey R. Brender et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2010)
Impaired Processing of Human Pro-Islet Amyloid Polypeptide Is Not a Causative Factor for Fibril Formation or Membrane Damage in Vitro
Lucie Khemtemourian et al.
BIOCHEMISTRY (2009)
Residual Structure in Islet Amyloid Polypeptide Mediates Its Interactions with Soluble Insulin
Lei Wei et al.
BIOCHEMISTRY (2009)
Insulin is a kinetic but not a thermodynamic inhibitor of amylin aggregation
Wei Cui et al.
FEBS JOURNAL (2009)
Three-Dimensional Structure and Orientation of Rat Islet Amyloid Polypeptide Protein in a Membrane Environment by Solution NMR Spectroscopy
Ravi Prakash Reddy Nanga et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2009)
Association of Highly Compact Type II Diabetes Related Islet Amyloid Polypeptide Intermediate Species at Physiological Temperature Revealed by Diffusion NMR Spectroscopy
Ronald Soong et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2009)
Atomic structures of IAPP (amylin) fusions suggest a mechanism for fibrillation and the role of insulin in the process
Jed J. W. Wiltzius et al.
PROTEIN SCIENCE (2009)
Structures of Rat and Human Islet Amyloid Polypeptide IAPP1-19 in Micelles by NMR Spectroscopy
Ravi Prakash Reddy Nanga et al.
BIOCHEMISTRY (2008)
A Single Mutation in the Nonamyloidogenic Region of Islet Amyloid Polypeptide Greatly Reduces Toxicity
Jeffrey R. Brender et al.
BIOCHEMISTRY (2008)
Amyloid fiber formation and membrane disruption are separate processes localized in two distinct regions of IAPP, the type-2-diabetes-related peptide
Jeffrey R. Brender et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2008)
Membrane damage by human islet amyloid polypeptide through fibril growth at the membrane
Maarten F. M. Engel et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Interaction of membrane-bound islet amyloid polypeptide with soluble and crystalline insulin
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PROTEIN SCIENCE (2008)
Membrane fragmentation by an amyloidogenic fragment of human Islet Amyloid Polypeptide detected by solid-state NMR spectroscopy of membrane nanotubes
Jeffrey R. Brender et al.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2007)
Impaired NH2-terminal processing of human proislet amyloid polypeptide by the prohormone convertase PC2 leads to amyloid formation and cell death
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DIABETES (2006)
Islet amyloid polypeptide inserts into phospholipid monolayers as monomer
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JOURNAL OF MOLECULAR BIOLOGY (2006)
Destabilization of human IAPP amyloid fibrils by proline mutations outside of the putative amyloidogenic domain: Is there a critical amyloidogenic domain in human IAPP?
A Abedini et al.
JOURNAL OF MOLECULAR BIOLOGY (2006)
Molecular mapping of the recognition interface between the islet amyloid polypeptide and insulin
Sharon Gilead et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2006)
The role of His-18 in amyloid formation by human islet amyloid polypeptide
A Abedini et al.
BIOCHEMISTRY (2005)
Zinc, the pancreas, and diabetes: Insights from rodent studies and future directions
CG Taylor
BIOMETALS (2005)
Amyloid ion channels: A common structural link for protein-misfolding disease
A Quist et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Aberrant processing of human proislet amyloid polypeptide results in increased amyloid formation
JF Paulsson et al.
DIABETES (2005)
Pancreatic β-cell granule peptides form heteromolecular complexes which inhibit islet amyloid polypeptide fibril formation
ETAS Jaikaran et al.
BIOCHEMICAL JOURNAL (2004)
The mechanism of insulin action on islet amyloid polypeptide fiber formation
JL Larson et al.
JOURNAL OF MOLECULAR BIOLOGY (2004)
Phospholipid catalysis of diabetic amyloid assembly
JD Knight et al.
JOURNAL OF MOLECULAR BIOLOGY (2004)
Islet amyloid: A critical entity in the pathogenesis of type 2 diabetes
RL Hull et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2004)
Permeabilization of lipid bilayers is a common conformation-dependent activity of soluble amyloid oligomers in protein misfolding diseases
R Kayed et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
The human islet amyloid polypeptide forms transient membrane-active prefibrillar assemblies
Y Porat et al.
BIOCHEMISTRY (2003)
Full-length rat amylin forms fibrils following substitution of single residues from human amylin
J Green et al.
JOURNAL OF MOLECULAR BIOLOGY (2003)
Molecular culprit may link diabetes, Alzheimer's and Parkinson's
[Anonymous]
MOLECULAR THERAPY (2003)
beta-cell deficit and increased beta-cell apoptosis in humans with type 2 diabetes
AE Butler et al.
DIABETES (2003)
Protofibrillar islet amyloid polypeptide permeabilizes synthetic vesicles by a pore-like mechanism that may be relevant to type II diabetes
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BIOCHEMISTRY (2002)