相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Time-trend evolution and determinants of sex ratio in Amyotrophic Lateral Sclerosis: a dose-response meta-analysis
Andrea Fontana et al.
JOURNAL OF NEUROLOGY (2021)
Sex-Specific Differences in Motor-Unit Remodeling in a Mouse Model of ALS
Eric Martineau et al.
ENEURO (2020)
Amyloid Precursor Protein Dimerisation Reduces Neurite Outgrowth
Luan Luu et al.
MOLECULAR NEUROBIOLOGY (2019)
Amyloid precursor protein and amyloid precursor-like protein 2 have distinct roles in modulating myelination, demyelination, and remyelination of axons
Phan H. Truong et al.
GLIA (2019)
Analysis of Motor Function in Amyloid Precursor-Like Protein 2 Knockout Mice: The Effects of Ageing and Sex
Phan H. Truong et al.
NEUROCHEMICAL RESEARCH (2019)
Sex Differences in Cancer: Epidemiology, Genetics and Therapy
Hae-In Kim et al.
BIOMOLECULES & THERAPEUTICS (2018)
The accumulation of enzymatically inactive cuproenzymes is a CNS-specific phenomenon of the SOD1G37R mouse model of ALS and can be restored by overexpressing the human copper transporter hCTR1
James B. Hilton et al.
EXPERIMENTAL NEUROLOGY (2018)
ALS Genes in the Genomic Era and their Implications for FTD
Hung Phuoc Nguyen et al.
TRENDS IN GENETICS (2018)
Sex: A Significant Risk Factor for Neurodevelopmental and Neurodegenerative Disorders
Paulo Pinares-Garcia et al.
BRAIN SCIENCES (2018)
Clinical Spectrum of Amyotrophic Lateral Sclerosis (ALS)
Leslie I. Grad et al.
COLD SPRING HARBOR PERSPECTIVES IN MEDICINE (2017)
Sex specific activation of the ERα axis of the mitochondrial UPR (UPRmt) in the G93A-SOD1 mouse model of familial ALS
Amanjot K. Riar et al.
HUMAN MOLECULAR GENETICS (2017)
Motor neurone disease: progress and challenges
Thanuja Dharmadasa et al.
MEDICAL JOURNAL OF AUSTRALIA (2017)
Not just amyloid: physiological functions of the amyloid precursor protein family
Ulrike C. Mueller et al.
NATURE REVIEWS NEUROSCIENCE (2017)
MECHANISTIC PATHWAYS OF SEX DIFFERENCES IN CARDIOVASCULAR DISEASE
Vera Regitz-Zagrosek et al.
PHYSIOLOGICAL REVIEWS (2017)
From first symptoms to diagnosis of amyotrophic lateral sclerosis: perspectives of an Irish informal caregiver cohort-a thematic analysis
Miriam Galvin et al.
BMJ OPEN (2017)
Protein Homeostasis in Amyotrophic Lateral Sclerosis: Therapeutic Opportunities?
Christopher P. Webster et al.
FRONTIERS IN MOLECULAR NEUROSCIENCE (2017)
Amyotrophic lateral sclerosis
Orla Hardiman et al.
NATURE REVIEWS DISEASE PRIMERS (2017)
Endogenous Cu in the central nervous system fails to satiate the elevated requirement for Cu in a mutant SOD1 mouse model of ALS
J. B. Hilton et al.
METALLOMICS (2016)
Amyloid Precursor-Like Protein 2 deletion-induced retinal synaptopathy related to congenital stationary night blindness: structural, functional and molecular characteristics
Virginie Dinet et al.
MOLECULAR BRAIN (2016)
The Neuroprotective Properties of the Amyloid Precursor Protein Following Traumatic Brain Injury
Stephanie Plummer et al.
AGING AND DISEASE (2016)
Emerging mechanisms of molecular pathology in ALS
Owen M. Peters et al.
JOURNAL OF CLINICAL INVESTIGATION (2015)
APLP2 Regulates Refractive Error and Myopia Development in Mice and Humans
Andrei V. Tkatchenko et al.
PLOS GENETICS (2015)
Mutant SOD1 Increases APP Expression and Phosphorylation in Cellular and Animal Models of ALS
Polina Rabinovich-Toidman et al.
PLOS ONE (2015)
Gender differences in autoimmune disease
S. T. Ngo et al.
FRONTIERS IN NEUROENDOCRINOLOGY (2014)
The neuroprotective activity of the amyloid precursor protein against traumatic brain injury is mediated via the heparin binding site in residues 96-110
Frances Corrigan et al.
JOURNAL OF NEUROCHEMISTRY (2014)
Insights into the physiological function of the β-amyloid precursor protein: beyond Alzheimer's disease
Edgar Dawkins et al.
JOURNAL OF NEUROCHEMISTRY (2014)
Differential role of APP and APLPs for neuromuscular synaptic morphology and function
Maja Klevanski et al.
MOLECULAR AND CELLULAR NEUROSCIENCE (2014)
Combined deletions of amyloid precursor protein and amyloid precursor-like protein 2 reveal different effects on mouse brain metal homeostasis
B. Elise Needham et al.
METALLOMICS (2014)
Amyloid precursor-like protein 2 suppresses irradiation-induced apoptosis in Ewing sarcoma cells and is elevated in immune-evasive Ewing sarcoma cells
Haley L. Peters et al.
CANCER BIOLOGY & THERAPY (2013)
PGC-1 is a male-specific disease modifier of human and experimental amyotrophic lateral sclerosis
Judith Eschbach et al.
HUMAN MOLECULAR GENETICS (2013)
APLP2 regulates neuronal stem cell differentiation during cortical development
S. Ali M. Shariati et al.
JOURNAL OF CELL SCIENCE (2013)
Human marrow stromal cells reduce microglial activation to protect motor neurons in a transgenic mouse model of amyotrophic lateral sclerosis
Chang Zhou et al.
JOURNAL OF NEUROINFLAMMATION (2013)
Characterization of early pathogenesis in the SOD1G93A mouse model of ALS: part II, results and discussion
Sharon Vinsant et al.
BRAIN AND BEHAVIOR (2013)
APLP2 regulates the expression of MHC class I molecules on irradiated Ewing's sarcoma cells
Haley L. Peters et al.
ONCOIMMUNOLOGY (2013)
Amyotrophic lateral sclerosis: A hormonal condition?
Helene Blasco et al.
AMYOTROPHIC LATERAL SCLEROSIS (2012)
Characterisation of the effect of knockout of the amyloid precursor protein on outcome following mild traumatic brain injury
Frances Corrigan et al.
BRAIN RESEARCH (2012)
Wild type TDP-43 induces neuro-inflammation and alters APP metabolism in lentiviral gene transfer models
Alexander M. Herman et al.
EXPERIMENTAL NEUROLOGY (2012)
Amyloid precursor protein (APP) contributes to pathology in the SOD1G93A mouse model of amyotrophic lateral sclerosis
J. Barney Bryson et al.
HUMAN MOLECULAR GENETICS (2012)
Relevance of amyloid precursor-like protein 2 C-terminal fragments in pancreatic cancer cells
Haley L. Peters et al.
INTERNATIONAL JOURNAL OF ONCOLOGY (2012)
PGC1α and mitochondrial metabolism - emerging concepts and relevance in ageing and neurodegenerative disorders
Shane Austin et al.
JOURNAL OF CELL SCIENCE (2012)
sAPPa rescues deficits in amyloid precursor protein knockout mice following focal traumatic brain injury
Frances Corrigan et al.
JOURNAL OF NEUROCHEMISTRY (2012)
APP involvement in retinogenesis of mice
Virginie Dinet et al.
ACTA NEUROPATHOLOGICA (2011)
p62 positive, TDP-43 negative, neuronal cytoplasmic and intranuclear inclusions in the cerebellum and hippocampus define the pathology of C9orf72-linked FTLD and MND/ALS
Safa Al-Sarraj et al.
ACTA NEUROPATHOLOGICA (2011)
Effect of genetic background on phenotype variability in transgenic mouse models of amyotrophic lateral sclerosis: A window of opportunity in the search for genetic modifiers
Terry D. Heiman-Patterson et al.
AMYOTROPHIC LATERAL SCLEROSIS (2011)
Genetic Rodent Models of Amyotrophic Lateral Sclerosis
L. Van den Bosch
JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY (2011)
Regulation of TDP-43 aggregation by phosphorylation andp62/SQSTM1
Owen A. Brady et al.
JOURNAL OF NEUROCHEMISTRY (2011)
Sex differences in the inflammatory response of primary astrocytes to lipopolysaccharide
María Santos-Galindo et al.
Biology of Sex Differences (2011)
Neuroprotective Function of Cellular Prion Protein in a Mouse Model of Amyotrophic Lateral Sclerosis
Petra Steinacker et al.
AMERICAN JOURNAL OF PATHOLOGY (2010)
The sex ratio in amyotrophic lateral sclerosis: A population based study
Zita R. Manjaly et al.
AMYOTROPHIC LATERAL SCLEROSIS (2010)
Guidelines for preclinical animal research in ALS/MND: A consensus meeting
Albert C. Ludolph et al.
AMYOTROPHIC LATERAL SCLEROSIS (2010)
Effects of Gender in Amyotrophic Lateral Sclerosis
Pamela A. McCombe et al.
GENDER MEDICINE (2010)
Peroxisome Proliferator-Activated Receptor gamma Coactivator-1 alpha Interacts with the Androgen Receptor (AR) and Promotes Prostate Cancer Cell Growth by Activating the AR
Masaki Shiota et al.
MOLECULAR ENDOCRINOLOGY (2010)
Neurons Generated from APP/APLP1/APLP2 Triple Knockout Embryonic Stem Cells Behave Normally in Vitro and in Vivo: Lack of Evidence for a Cell Autonomous Role of the Amyloid Precursor Protein in Neuronal Differentiation
Bruno A. Bergmans et al.
STEM CELLS (2010)
Concentrations of beta-amyloid precursor protein processing products in cerebrospinal fluid of patients with amyotrophic lateral sclerosis and frontotemporal lobar degeneration
Petra Steinacker et al.
JOURNAL OF NEURAL TRANSMISSION (2009)
Expression of amyloid precursor protein after rat traumatic brain injury
Tatsuki Itoh et al.
NEUROLOGICAL RESEARCH (2009)
Epidemiology of ALS in Italy A 10-year prospective population-based study
A. Chio et al.
NEUROLOGY (2009)
Analysis of survival and prognostic factors in amyotrophic lateral sclerosis: a population based study
S. Zoccolella et al.
JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY (2008)
Identification of the Alzheimer's disease amyloid precursor protein (APP) and its homologue APLP2 as essential modulators of glucose and insulin homeostasis and growth
B. E. Needham et al.
JOURNAL OF PATHOLOGY (2008)
Effects of estrogen on lifespan and motor functions in female hSOD1 G93A transgenic mice
Chan-Il Choi et al.
JOURNAL OF THE NEUROLOGICAL SCIENCES (2008)
Deletion of the BH3-only protein puma protects motoneurons from ER stress-induced apoptosis and delays motoneuron loss in ALS mice
Dairin Kieran et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Role of P450 aromatase in sex-specific astrocytic cell death
Mingyue Liu et al.
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM (2007)
PGC-1α:: a key regulator of energy metabolism
Huiyun Liang et al.
ADVANCES IN PHYSIOLOGY EDUCATION (2006)
Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis
Manuela Neumann et al.
SCIENCE (2006)
Elevated levels of amyloid precursor protein in muscle of patients with amyotrophic lateral sclerosis and a mouse model of the disease
Hannu Koistinen et al.
MUSCLE & NERVE (2006)
Complete dissociation of motor neuron death from motor dysfunction by Bax deletion in a mouse model of ALS
Thomas W. Gould et al.
JOURNAL OF NEUROSCIENCE (2006)
Soluble amyloid precursor protein a reduces neuronal injury and improves functional outcome following diffuse traumatic brain injury in rats
Emma Thornton et al.
BRAIN RESEARCH (2006)
Selective vulnerability and pruning of phasic motoneuron axons in motoneuron disease alleviated by CNTF
S Pun et al.
NATURE NEUROSCIENCE (2006)
Background and gender effects on survival in the TgN(SOD1-G93A) 1 Gur mouse model of ALS
TD Heiman-Patterson et al.
JOURNAL OF THE NEUROLOGICAL SCIENCES (2005)
Reduced synaptic vesicle density and active zone size in mice lacking amyloid precursor protein (APP) and APP-like protein 2
G Yang et al.
NEUROSCIENCE LETTERS (2005)
Optimal methods to characterize the G93A mouse model of ALS
FJ Miana-Mena et al.
AMYOTROPHIC LATERAL SCLEROSIS (2005)
Defective neuromuscular synapses in mice lacking amyloid precursor protein (APP) and APP-like protein 2
P Wang et al.
JOURNAL OF NEUROSCIENCE (2005)
Effect of transgene copy number on survival in the G93A SOD1 transgenic mouse model of ALS
GM Alexander et al.
MOLECULAR BRAIN RESEARCH (2004)
Cortical dysplasia resembling human type 2 lissencephaly in mice lacking all three APP family members
J Herms et al.
EMBO JOURNAL (2004)
Transcriptomic changes in human breast cancer progression as determined by serial analysis of gene expression
MC Abba et al.
BREAST CANCER RESEARCH (2004)
Modulation of estrogen receptor-α transcriptional activity by the coactivator PGC-1
I Tcherepanova et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Survival of motor neurons and expression of β-amyloid protein in the aged rat spinal cord
YY Xie et al.
NEUROREPORT (2000)
Developmental regulation of amyloid precursor protein at the neuromuscular junction in mouse skeletal muscle
M Akaaboune et al.
MOLECULAR AND CELLULAR NEUROSCIENCE (2000)