4.8 Article

Tumor-derived exosomes drive immunosuppressive macrophages in a pre-metastatic niche through glycolytic dominant metabolic reprogramming

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Multidisciplinary Sciences

A conformational switch driven by phosphorylation regulates the activity of the evolutionarily conserved SNARE Ykt6

Kaitlyn McGrath et al.

Summary: Ykt6, a soluble SNARE protein, plays a critical role in vesicular fusion pathways. Phosphorylation at a conserved site triggers a conformational change, leading to altered protein interactions and enhanced toxicity in PD models. This study reveals a mechanism regulating Ykt6 conformation and activity with potential implications for Parkinson's disease.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2021)

Review Biochemistry & Molecular Biology

Exosomes in the tumor microenvironment as mediators of cancer therapy resistance

Irene Li et al.

MOLECULAR CANCER (2019)

Article Biochemistry & Molecular Biology

Suppression of Exosomal PD-L1 Induces Systemic Anti-tumor Immunity and Memory

Mauro Poggio et al.

Article Biochemistry & Molecular Biology

c-Met and PD-L1 on Circulating Exosomes as Diagnostic and Prognostic Markers for Pancreatic Cancer

Alexander Lux et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2019)

Article Multidisciplinary Sciences

Immune evasion before tumour invasion in early lung squamous carcinogenesis

Celine Mascaux et al.

NATURE (2019)

Review Biochemistry & Molecular Biology

Exosomes promote pre-metastatic niche formation in ovarian cancer

Wenlong Feng et al.

MOLECULAR CANCER (2019)

Article Multidisciplinary Sciences

Metabolic regulation of gene expression by histone lactylation

Di Zhang et al.

NATURE (2019)

Article Gastroenterology & Hepatology

Macrophage depletion using clodronate liposomes decreases tumorigenesis and alters gut microbiota in the AOM/DSS mouse model of colon cancer

Jackie E. Bader et al.

AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2018)

Article Biochemistry & Molecular Biology

Melanoma exosomes promote mixed M1 and M2 macrophage polarization

Gina T. Bardi et al.

CYTOKINE (2018)

Article Medicine, Research & Experimental

PD-L1 on host cells is essential for PD-L1 blockade-mediated tumor regression

Haidong Tang et al.

JOURNAL OF CLINICAL INVESTIGATION (2018)

Article Medicine, Research & Experimental

Host expression of PD-L1 determines efficacy of PD-L1 pathway blockade-mediated tumor regression

Heng Lin et al.

JOURNAL OF CLINICAL INVESTIGATION (2018)

Article Biochemistry & Molecular Biology

Ligation of free HMGB1 to TLR2 in the absence of ligand is negatively regulated by the C-terminal tail domain

Hannah Aucott et al.

MOLECULAR MEDICINE (2018)

Review Biochemistry & Molecular Biology

Understanding the tumor immune microenvironment (TIME) for effective therapy

Mikhail Binnewies et al.

NATURE MEDICINE (2018)

Review Cell Biology

Shedding light on the cell biology of extracellular vesicles

Guillaume van Niel et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2018)

Article Multidisciplinary Sciences

Macrophages orchestrate breast cancer early dissemination and metastasis

Nina Linde et al.

NATURE COMMUNICATIONS (2018)

Article Multidisciplinary Sciences

Immune evasion mediated by PD-L1 on glioblastoma-derived extracellular vesicles

Franz L. Ricklefs et al.

SCIENCE ADVANCES (2018)

Article Biochemistry & Molecular Biology

Tumor-derived exosomes induce N2 polarization of neutrophils to promote gastric cancer cell migration

Xu Zhang et al.

MOLECULAR CANCER (2018)

Article Oncology

Clinical Significance of PD-L1+ Exosomes in Plasma of Head and Neck Cancer Patients

Marie-Nicole Theodoraki et al.

CLINICAL CANCER RESEARCH (2018)

Review Multidisciplinary Sciences

The biology and management of non-small cell lung cancer

Roy S. Herbst et al.

NATURE (2018)

Review Biochemistry & Molecular Biology

Current knowledge on exosome biogenesis and release

Nina Pettersen Hessvik et al.

CELLULAR AND MOLECULAR LIFE SCIENCES (2018)

Review Oncology

Nitric Oxide: The Forgotten Child of Tumor Metabolism

Bahar Salimian Rizi et al.

TRENDS IN CANCER (2017)

Article Immunology

Tumor-derived exosomes modulate PD-L1 expression in monocytes

Franziska Haderk et al.

SCIENCE IMMUNOLOGY (2017)

Review Oncology

Cancer Tills the Premetastatic Field: Mechanistic Basis and Clinical Implications

Andrew R. Chin et al.

CLINICAL CANCER RESEARCH (2016)

Article Pharmacology & Pharmacy

Mechanisms for the activation of Toll-like receptor 2/4 by saturated fatty acids and inhibition by docosahexaenoic acid

Daniel H. Hwang et al.

EUROPEAN JOURNAL OF PHARMACOLOGY (2016)

Review Medicine, Research & Experimental

The biology and function of exosomes in cancer

Raghu Kalluri

JOURNAL OF CLINICAL INVESTIGATION (2016)

Article Multidisciplinary Sciences

Visualization of immediate immune responses to pioneer metastatic cells in the lung

Mark B. Headley et al.

NATURE (2016)

Article Multidisciplinary Sciences

Tumour exosome integrins determine organotropic metastasis

Ayuko Hoshino et al.

NATURE (2015)

Article Medicine, General & Internal

Nivolumab versus Docetaxel in Advanced Nonsquamous Non-Small-Cell Lung Cancer

H. Borghaei et al.

NEW ENGLAND JOURNAL OF MEDICINE (2015)

Review Biochemical Research Methods

Exosomes in bodily fluids are a highly stable resource of disease biomarkers

Stephanie Boukouris et al.

PROTEOMICS CLINICAL APPLICATIONS (2015)

Article Multidisciplinary Sciences

Novel Markers to Delineate Murine M1 and M2 Macrophages

Kyle A. Jablonski et al.

PLOS ONE (2015)

Article Multidisciplinary Sciences

Functional polarization of tumour-associated macrophages by tumour-derived lactic acid

Oscar R. Colegio et al.

NATURE (2014)

Article Biochemistry & Molecular Biology

Body Fluid Exosomes Promote Secretion of Inflammatory Cytokines in Monocytic Cells via Toll-like Receptor Signaling

Niko P. Bretz et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2013)

Article Medicine, Research & Experimental

Macrophage plasticity and polarization: in vivo veritas

Antonio Sica et al.

JOURNAL OF CLINICAL INVESTIGATION (2012)

Article Biochemistry & Molecular Biology

Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET

Hector Peinado et al.

NATURE MEDICINE (2012)

Article Pathology

TLR2-Mediated Expansion of MDSCs Is Dependent on the Source of Tumor Exosomes

Xiaoyu Xiang et al.

AMERICAN JOURNAL OF PATHOLOGY (2010)

Article Critical Care Medicine

HMGB1 signals through toll-like receptor (TLR) 4 and TLR2

Man Yu et al.

Article Radiology, Nuclear Medicine & Medical Imaging

Atypical pulmonary metastases: Spectrum of radiologic findings

JB Seo et al.

RADIOGRAPHICS (2001)