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Enteric viruses seize their immunomodulatory niche

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CELL HOST & MICROBE
卷 29, 期 6, 页码 858-861

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CELL PRESS
DOI: 10.1016/j.chom.2021.05.007

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  1. NIH [T32 DK07765329, R01 OD024917, R01 AI139314, R01 AI141716, R01 AI141478]

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The study reveals that enteric eukaryotic viruses play an immunomodulatory role in the healthy intestinal microbiota, and using a single virus infection approach, it uncovers both generalized viral immune responses and numerous unique, virus-specific response profiles.
Enteric eukaryotic viruses are increasingly recognized as non-pathogenic, immunomodulatory participants in the healthy intestinal microbiota. In this issue of Cell Host & Microbe, Dallari et al. (2021) use a single virus infection approach to reveal both generalized viral immune responses and numerous unique, virus-specific response profiles.

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