相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。NINJ1 mediates plasma membrane rupture during lytic cell death
Nobuhiko Kayagaki et al.
NATURE (2021)
Loss of COPZ1 induces NCOA4 mediated autophagy and ferroptosis in glioblastoma cell lines
Yulin Zhang et al.
ONCOGENE (2021)
Ibuprofen induces ferroptosis of glioblastoma cells via downregulation of nuclear factor erythroid 2-related factor 2 signaling pathway
Xingchun Gao et al.
ANTI-CANCER DRUGS (2020)
CuII(atsm) inhibits ferroptosis: Implications for treatment of neurodegenerative disease
Adam Southon et al.
BRITISH JOURNAL OF PHARMACOLOGY (2020)
The necroptosis machinery mediates axonal degeneration in a model of Parkinson disease
Maritza Onate et al.
CELL DEATH AND DIFFERENTIATION (2020)
Necroptosis is dispensable for motor neuron degeneration in a mouse model of ALS
Taide Wang et al.
CELL DEATH AND DIFFERENTIATION (2020)
Autophagy and disease: unanswered questions
Ying Yang et al.
CELL DEATH AND DIFFERENTIATION (2020)
Bim contributes to the progression of Huntington's disease-associated phenotypes
Sheridan L. Roberts et al.
HUMAN MOLECULAR GENETICS (2020)
Dihydroartemisinin initiates ferroptosis in glioblastoma through GPX4 inhibition
Renxin Yi et al.
BIOSCIENCE REPORTS (2020)
GTP Cyclohydrolase 1/Tetrahydrobiopterin Counteract Ferroptosis through Lipid Remodeling
Vanessa A. N. Kraft et al.
ACS CENTRAL SCIENCE (2020)
RIPK3 is a novel prognostic marker for lower grade glioma and further enriches IDH mutational status subgrouping
Guilherme Afonso Vergara et al.
JOURNAL OF NEURO-ONCOLOGY (2020)
Autophosphorylation at serine 166 regulates RIP kinase 1-mediated cell death and inflammation
Lucie Laurien et al.
NATURE COMMUNICATIONS (2020)
Flexible Usage and Interconnectivity of Diverse Cell Death Pathways Protect against Intracellular Infection
Marcel Doerflinger et al.
IMMUNITY (2020)
Ferroptosis-Related Gene Signature Predicts Glioma Cell Death and Glioma Patient Progression
Han-jie Liu et al.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (2020)
MLKL trafficking and accumulation at the plasma membrane control the kinetics and threshold for necroptosis
Andre L. Samson et al.
NATURE COMMUNICATIONS (2020)
Caspase Activation and Caspase-Mediated Cleavage of APP Is Associated with Amyloid β-Protein-Induced Synapse Loss in Alzheimer's Disease
Goonho Park et al.
CELL REPORTS (2020)
Emerging connectivity of programmed cell death pathways and its physiological implications
Sammy Bedoui et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2020)
Trial of Sodium Phenylbutyrate-Taurursodiol for Amyotrophic Lateral Sclerosis
Sabrina Paganoni et al.
NEW ENGLAND JOURNAL OF MEDICINE (2020)
The Iron Chelator Deferiprone Improves the Phenotype in a Mouse Model of Tauopathy (vol 77, pg 753, 2020)
Shalini S. Rao et al.
JOURNAL OF ALZHEIMERS DISEASE (2020)
Neutrophil-induced ferroptosis promotes tumor necrosis in glioblastoma progression
Patricia P. Yee et al.
NATURE COMMUNICATIONS (2020)
Phase I/IIa study of concomitant radiotherapy with olaparib and temozolomide in unresectable or partially resectable glioblastoma: OLA-TMZ-RTE-01 trial protocol
Paul Lesueur et al.
BMC CANCER (2019)
The role of necroptosis in cancer: A double-edged sword?
Xia Qin et al.
BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER (2019)
The Coming Decade of Cell Death Research: Five Riddles
Douglas R. Green
CELL (2019)
Inflammasomes in neuroinflammatory and neurodegenerative diseases
Sofie Voet et al.
EMBO MOLECULAR MEDICINE (2019)
The role of necroptosis in cancer biology and therapy
Yitao Gong et al.
MOLECULAR CANCER (2019)
Cell death-mediated cytokine release and its therapeutic implications
David E. Place et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2019)
Upregulated necroptosis-pathway-associated genes are unfavorable prognostic markers in low-grade glioma and glioblastoma multiforme
Yuanli Doug et al.
TRANSLATIONAL CANCER RESEARCH (2019)
Targeting Autophagy for Overcoming Resistance to Anti-EGFR Treatments
Yoojung Kwon et al.
CANCERS (2019)
FSP1 is a glutathione-independent ferroptosis suppressor
Sebastian Doll et al.
NATURE (2019)
The CoQ oxidoreductase FSP1 acts parallel to GPX4 to inhibit ferroptosis
Kirill Bersuker et al.
NATURE (2019)
Mcl-1 and Bcl-xL are essential for survival of the developing nervous system
Lauren C. Fogarty et al.
CELL DEATH AND DIFFERENTIATION (2019)
Parkin inhibits BAK and BAX apoptotic function by distinct mechanisms during mitophagy
Jonathan P. Bernardini et al.
EMBO JOURNAL (2019)
Regulation of apoptosis in health and disease: the balancing act of BCL-2 family proteins
Rumani Singh et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2019)
Could Conservative Iron Chelation Lead to Neuroprotection in Amyotrophic Lateral Sclerosis?
Caroline Moreau et al.
ANTIOXIDANTS & REDOX SIGNALING (2018)
Embryogenesis and Adult Life in the Absence of Intrinsic Apoptosis Effectors BAX, BAK, and BOK
Francine F. S. Ke et al.
CELL (2018)
Cell Death Mechanisms in Stroke and Novel Molecular and Cellular Treatment Options
Emine Sekerdag et al.
CURRENT NEUROPHARMACOLOGY (2018)
Nano-targeted induction of dual ferroptotic mechanisms eradicates high-risk neuroblastoma
Behrouz Hassannia et al.
JOURNAL OF CLINICAL INVESTIGATION (2018)
Rapamycin treatment for amyotrophic lateral sclerosis Protocol for a phase II randomized, double-blind, placebo-controlled, multicenter, clinical trial (RAP-ALS trial)
Jessica Mandrioli et al.
MEDICINE (2018)
Microglia-targeted candidates push the Alzheimer drug
Asher Mullard
NATURE REVIEWS DRUG DISCOVERY (2018)
Glioblastoma and chemoresistance to alkylating agents: Involvement of apoptosis, autophagy, and unfolded protein response
Sabine Hombach-Klonisch et al.
PHARMACOLOGY & THERAPEUTICS (2018)
Caspase-1 inhibition prevents glial inflammasome activation and pyroptosis in models of multiple sclerosis
Brienne A. McKenzie et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2018)
Pharmacological Inhibition of Necroptosis Protects from Dopaminergic Neuronal Cell Death in Parkinson's Disease Models
Angelo Iannielli et al.
CELL REPORTS (2018)
Resolving the Role of Lipoxygenases in the Initiation and Execution of Ferroptosis
Ron Shah et al.
ACS CENTRAL SCIENCE (2018)
Glutathione peroxidase 4 participates in secondary brain injury through mediating ferroptosis in a rat model of intracerebral hemorrhage
Zhuwei Zhang et al.
BRAIN RESEARCH (2018)
Protein misfolding, aggregation, and conformational strains in neurodegenerative diseases
Claudio Soto et al.
NATURE NEUROSCIENCE (2018)
Subtle Changes in the Levels of BCL-2 Proteins Cause Severe Craniofacial Abnormalities
Stephanie Grabow et al.
CELL REPORTS (2018)
Nec-1 alleviates cognitive impairment with reduction of A and tau abnormalities in APP/PS1 mice
Seung-Hoon Yang et al.
EMBO MOLECULAR MEDICINE (2017)
ACSL4 dictates ferroptosis sensitivity by shaping cellular lipid composition
Sebastian Doll et al.
NATURE CHEMICAL BIOLOGY (2017)
Autophagy in cancer metastasis
E. E. Mowers et al.
ONCOGENE (2017)
Caspase-8: regulating life and death
Bart Tummers et al.
IMMUNOLOGICAL REVIEWS (2017)
Tau-mediated iron export prevents ferroptotic damage after ischemic stroke
Q-z Tuo et al.
MOLECULAR PSYCHIATRY (2017)
Necroptosis activation in Alzheimer's disease
Antonella Caccamo et al.
NATURE NEUROSCIENCE (2017)
Distinct roles for motor neuron autophagy early and late in the SOD1G93A mouse model of ALS
Noam D. Rudnick et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)
RIPK1 mediates a disease-associated microglial response in Alzheimer's disease
Dimitry Ofengeim et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)
Ablation of ferroptosis regulator glutathione peroxidase 4 in forebrain neurons promotes cognitive impairment and neurodegeneration
William Sealy Hambright et al.
REDOX BIOLOGY (2017)
Brain iron chelation by deferiprone in a phase 2 randomised double-blinded placebo controlled clinical trial in Parkinson's disease
Antonio Martin-Bastida et al.
SCIENTIFIC REPORTS (2017)
Deferoxamine enhances alternative activation of microglia and inhibits amyloid beta deposits in APP/PS1 mice
Yun Zhang et al.
BRAIN RESEARCH (2017)
Autophagy flux in CA1 neurons of Alzheimer hippocampus: Increased induction overburdens failing lysosomes to propel neuritic dystrophy
Matteo Bordi et al.
AUTOPHAGY (2016)
Innate immune signaling through differential RIPK1 expression promote tumor progression in head and neck squamous cell carcinoma
Kevin D. McCormick et al.
CARCINOGENESIS (2016)
Advances in the Development of Disease-Modifying Treatments for Amyotrophic Lateral Sclerosis
Diane Moujalled et al.
CNS DRUGS (2016)
The Pseudokinase MLKL and the Kinase RIPK3 Have Distinct Roles in Autoimmune Disease Caused by Loss of Death-Receptor-Induced Apoptosis
Silvia Alvarez-Diaz et al.
IMMUNITY (2016)
ULK1-mediated phosphorylation of ATG14 promotes autophagy and is impaired in Huntington's disease models
Mitchell S. Wold et al.
MOLECULAR NEURODEGENERATION (2016)
Pore-forming activity and structural autoinhibition of the gasdermin family
Jingjin Ding et al.
NATURE (2016)
Ferroptosis, a newly characterized form of cell death in Parkinson's disease that is regulated by PKC
Bruce Do Van et al.
NEUROBIOLOGY OF DISEASE (2016)
Sulfasalazine impacts on ferroptotic cell death and alleviates the tumor microenvironment and glioma-induced brain edema
Tina Sehm et al.
ONCOTARGET (2016)
Temozolomide toxicity operates in a xCT/SLC7a11 dependent manner and is fostered by ferroptosis
Tina Sehm et al.
ONCOTARGET (2016)
Diagnostic and clinical relevance of the autophago-lysosomal network in human gliomas
Lukas Jennewein et al.
ONCOTARGET (2016)
Human Haploid Cell Genetics Reveals Roles for Lipid Metabolism Genes in Nonapoptotic Cell Death
Scott J. Dixon et al.
ACS CHEMICAL BIOLOGY (2015)
Effects of Iron Ions and Iron Chelation on the Efficiency of Experimental Radiotherapy of Animals with Gliomas
S. D. Ivanov et al.
BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE (2015)
Ablation of the Ferroptosis Inhibitor Glutathione Peroxidase 4 in Neurons Results in Rapid Motor Neuron Degeneration and Paralysis
Liuji Chen et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2015)
Autophagy induction impairs migration and invasion by reversing EMT in glioblastoma cells
Myriam Catalano et al.
MOLECULAR ONCOLOGY (2015)
Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death
Jianjin Shi et al.
NATURE (2015)
Randomized phase 2 study of carboplatin and bevacizumab in recurrent glioblastoma
Kathryn M. Field et al.
NEURO-ONCOLOGY (2015)
Necrostatin-1 Ameliorates Intracerebral Hemorrhage-Induced Brain Injury in Mice Through Inhibiting RIP1/RIP3 Pathway
Xingfen Su et al.
NEUROCHEMICAL RESEARCH (2015)
A randomized, double-blind, placebo-controlled trial of resveratrol for Alzheimer disease
R. Scott Turner et al.
NEUROLOGY (2015)
Adenovirus expressing dual c-Met-specific shRNA exhibits potent antitumor effect through autophagic cell death accompanied by senescence-like phenotypes in glioblastoma cells
Jung-Sun Lee et al.
ONCOTARGET (2015)
Depletion of p62 reduces nuclear inclusions and paradoxically ameliorates disease phenotypes in Huntington's model mice
Masaru Kurosawa et al.
HUMAN MOLECULAR GENETICS (2015)
Targeting Chelatable Iron as a Therapeutic Modality in Parkinson's Disease
David Devos et al.
ANTIOXIDANTS & REDOX SIGNALING (2014)
Regulation of Ferroptotic Cancer Cell Death by GPX4
Wan Seok Yang et al.
CELL (2014)
Historical landmarks of autophagy research
Yoshinori Ohsumi
CELL RESEARCH (2014)
Emerging treatment strategies for glioblastoma multiforme
Steven K. Carlsson et al.
EMBO MOLECULAR MEDICINE (2014)
Ferrostatins Inhibit Oxidative Lipid Damage and Cell Death in Diverse Disease Models
Rachid Skouta et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2014)
Ischemic insults induce necroptotic cell death in hippocampal neurons through the up-regulation of endogenous RIP3
M. Vieira et al.
NEUROBIOLOGY OF DISEASE (2014)
RIP1 potentiates BPDE-induced transformation in human bronchial epithelial cells through catalase-mediated suppression of excessive reactive oxygen species
Qiong Wang et al.
CARCINOGENESIS (2013)
The Pseudokinase MLKL Mediates Necroptosis via a Molecular Switch Mechanism
James M. Murphy et al.
IMMUNITY (2013)
Intranasal deferoxamine reverses iron-induced memory deficits and inhibits amyloidogenic APP processing in a transgenic mouse model of Alzheimer's disease
Chuang Guo et al.
NEUROBIOLOGY OF AGING (2013)
Loss of PDCD4 contributes to enhanced chemoresistance in Glioblastoma Multiforme through de-repression of Bcl-xL translation
Urszula Liwak et al.
ONCOTARGET (2013)
Hypoxia-Induced Autophagy Promotes Tumor Cell Survival and Adaptation to Antiangiogenic Treatment in Glioblastoma
Yu-Long Hu et al.
CANCER RESEARCH (2012)
Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death
Scott J. Dixon et al.
CELL (2012)
Mixed Lineage Kinase Domain-like Protein Mediates Necrosis Signaling Downstream of RIP3 Kinase
Liming Sun et al.
CELL (2012)
Many stimuli pull the necrotic trigger, an overview
N. Vanlangenakker et al.
CELL DEATH AND DIFFERENTIATION (2012)
Disrupted Autophagy Leads to Dopaminergic Axon and Dendrite Degeneration and Promotes Presynaptic Accumulation of α-Synuclein and LRRK2 in the Brain
Lauren G. Friedman et al.
JOURNAL OF NEUROSCIENCE (2012)
Genetics of Parkinson's Disease
Christine Klein et al.
COLD SPRING HARBOR PERSPECTIVES IN MEDICINE (2012)
Necrostatin decreases oxidative damage, inflammation, and injury after neonatal HI
Frances J. Northington et al.
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM (2011)
Autophagy in Spinal Cord Motor Neurons in Sporadic Amyotrophic Lateral Sclerosis
Shoichi Sasaki
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2011)
Amyotrophic lateral sclerosis
Matthew C. Kiernan et al.
LANCET (2011)
Molecular pathways of motor neuron injury in amyotrophic lateral sclerosis
Laura Ferraiuolo et al.
NATURE REVIEWS NEUROLOGY (2011)
Necrostatin-1 ameliorates symptoms in R6/2 transgenic mouse model of Huntington's disease
S. Zhu et al.
CELL DEATH & DISEASE (2011)
Neuropathological Alterations in Alzheimer Disease
Alberto Serrano-Pozo et al.
COLD SPRING HARBOR PERSPECTIVES IN MEDICINE (2011)
Upregulation of Bax protein and increased DNA degradation in ALS spinal cord motor neurons
T. Ekegren et al.
ACTA NEUROLOGICA SCANDINAVICA (2010)
Mechanisms Underlying Inflammation in Neurodegeneration
Christopher K. Glass et al.
CELL (2010)
BimEL as a possible molecular link between proteasome dysfunction and cell death induced by mutant huntingtin
Rebecca Leon et al.
EUROPEAN JOURNAL OF NEUROSCIENCE (2010)
Blocking the mitochondrial apoptotic pathway preserves motor neuron viability and function in a mouse model of amyotrophic lateral sclerosis
Nichole A. Reyes et al.
JOURNAL OF CLINICAL INVESTIGATION (2010)
Molecular mechanisms of excitotoxicity and their relevance to pathogenesis of neurodegenerative diseases
Xiao-xia Dong et al.
ACTA PHARMACOLOGICA SINICA (2009)
Minocycline and neurodegenerative diseases
Hye-Sun Kim et al.
BEHAVIOURAL BRAIN RESEARCH (2009)
The Receptor Interacting Protein 1 Inhibits p53 Induction through NF-κB Activation and Confers a Worse Prognosis in Glioblastoma
Seongmi Park et al.
CANCER RESEARCH (2009)
Classification of cell death: recommendations of the Nomenclature Committee on Cell Death 2009
G. Kroemer et al.
CELL DEATH AND DIFFERENTIATION (2009)
The genetics of Parkinson's syndromes: a critical review
John Hardy et al.
CURRENT OPINION IN GENETICS & DEVELOPMENT (2009)
The Many Roles of FAS Receptor Signaling in the Immune System
Andreas Strasser et al.
IMMUNITY (2009)
Neuronal cell death in neurodegenerative diseases: recurring themes around protein handling
Adrienne M. Gorman
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2008)
Mcl-1 is a key regulator of apoptosis during CNS development and after DNA damage
Nicole Arbour et al.
JOURNAL OF NEUROSCIENCE (2008)
Autophagy induction and autophagosome clearance in neurons: Relationship to autophagic pathology in Alzheimer's disease
Barry Boland et al.
JOURNAL OF NEUROSCIENCE (2008)
Bcl2L12-mediated inhibition of effector caspase-3 and caspase-7 via distinct mechanisms in glioblastoma
Alexander H. Stegh et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Increased autophagy in transgenic mice with a G93A mutant SOD1 gene
Nobutoshi Morimoto et al.
BRAIN RESEARCH (2007)
The proapoptotic BCL-2 family member BIM mediates motoneuron loss in a model of amyotrophic lateral sclerosis
C. Hetz et al.
CELL DEATH AND DIFFERENTIATION (2007)
Apoptotic mechanisms in mutant LRRK2-mediated cell death
Ciro Iaccarino et al.
HUMAN MOLECULAR GENETICS (2007)
Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases
Michael T. Lin et al.
NATURE (2006)
ALS:: A disease of motor neurons and their nonneuronal neighbors
Sverine Boillee et al.
NEURON (2006)
Extrinsic versus intrinsic apoptosis pathways in anticancer chemotherapy
S. Fulda et al.
ONCOGENE (2006)
Adding chloroquine to conventional treatment for glioblastoma multiforme -: A randomized, double-blind, placebo-controlled trial
J Sotelo et al.
ANNALS OF INTERNAL MEDICINE (2006)
Expression pattern of apoptosis-related markers in Huntington's disease
JC Vis et al.
ACTA NEUROPATHOLOGICA (2005)
Differential targeting of prosurvival Bcl-2 proteins by their BH3-only ligands allows complementary apoptotic function
L Chen et al.
MOLECULAR CELL (2005)
Intracellular Aβ42 activates p53 promoter: a pathway to neurodegeneration in Alzheimer's disease
Y Ohyagi et al.
FASEB JOURNAL (2005)
Amyotrophic lateral sclerosis-associated SOD1 mutant proteins bind and aggregate with Bcl-2 in spinal cord mitochondria
P Pasinelli et al.
NEURON (2004)
Intracellular Aβ42 activates p53 promoter:: a pathway to neurodegeneration in Alzheimer's disease
Y Ohyagi et al.
FASEB JOURNAL (2004)
Inhibition of mTOR induces autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington disease
B Ravikumar et al.
NATURE GENETICS (2004)
Down-regulation of Bcl-2 and Bcl-xL expression with bispecific antisense treatment in glioblastoma cell lines induce cell death
ZH Jiang et al.
JOURNAL OF NEUROCHEMISTRY (2003)
Sequential activation of individual caspases, and of alterations in Bcl-2 proapoptotic signals in a mouse model of Huntington's disease
Y Zhang et al.
JOURNAL OF NEUROCHEMISTRY (2003)
Caspase cleavage of the amyloid precursor protein modulates amyloid beta-protein toxicity
DC Lu et al.
JOURNAL OF NEUROCHEMISTRY (2003)
Keeping killers on a tight leash: transcriptional and posttranslational control of the pro-apoptotic activity of BH3-only proteins
H Puthalakath et al.
CELL DEATH AND DIFFERENTIATION (2002)
Selective cytotoxicity of intracellular amyloid β peptide1-42 through p53 and Bax in cultured primary human neurons
Y Zhang et al.
JOURNAL OF CELL BIOLOGY (2002)
Mechanisms of caspase activation and inhibition during apoptosis
YG Shi
MOLECULAR CELL (2002)
Increased caspase 3 and Bax immunoreactivity accompany nuclear GAPDH translocation and neuronal apoptosis in Parkinson's disease
NA Tatton
EXPERIMENTAL NEUROLOGY (2000)
Alteration of the Bcl-x/Bax ratio in a transgenic mouse model of amyotrophic lateral sclerosis:: Evidence for the implication of the p53 signaling pathway
JLG de Aguilar et al.
NEUROBIOLOGY OF DISEASE (2000)
Apoptotic pathways: Paper wraps stone blunts scissors
DR Green
CELL (2000)
Mechanisms of programmed cell death in the developing brain
CY Kuan et al.
TRENDS IN NEUROSCIENCES (2000)
Functional role of caspase-1 and caspase-3 in an ALS transgenic mouse model
MW Li et al.
SCIENCE (2000)