期刊
CATALYSIS LETTERS
卷 152, 期 3, 页码 791-798出版社
SPRINGER
DOI: 10.1007/s10562-021-03670-0
关键词
Multidimensional group testing; Deconvolution; Combinatorial chemistry; Suzuki cross-coupling; High-throughput
资金
- National Research Foundation of South Africa [5386]
- University of Johannesburg
This study utilized a multidimensional group testing approach for deconvoluting reagents in a Suzuki cross-coupling reaction, aiming to accelerate the identification of the optimal reagents. Through two deconvolution approaches, it was determined that K2CO3, ethanol, and benzyldiphenylphosphine were the optimal reagents. This approach enables faster identification of optimal reagents and greatly reduces the number of reactions required.
A multidimensional group testing approach was utilised for the deconvolution of reagents for a Suzuki cross-coupling reaction. This proof of concept aimed to accelerate the identification of the best reagents for such a reaction. Two deconvolution approaches showed that K2CO3, ethanol and benzyldiphenylphosphine were the optimal reagents. With this approach, the optimal reagents are identified faster, and the number of reactions is drastically reduced. [GRAPHICS] .
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据