4.5 Article

Visualization of the cancer cell cycle by tissue-clearing technology using the Fucci reporter system

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Oncology

Neurotensin receptor 1 signaling promotes pancreatic cancer progression

Kei Takahashi et al.

Summary: The study identified NTSR1 as a potential prognostic marker and molecular target for pancreatic cancer treatment, as its overexpression was associated with poor prognosis and increased tumorigenic and metastatic abilities. Additionally, NTS stimulation activated the MAPK and NF-kappa B signaling pathways in highly malignant cancer sublines and revealed new target genes for NTS in pancreatic cancer cells. Treatment with a selective NTSR1 antagonist suppressed the activation of these pathways and attenuated the tumorigenicity of pancreatic cancer cells.

MOLECULAR ONCOLOGY (2021)

Article Multidisciplinary Sciences

Malignant subclone drives metastasis of genetically and phenotypically heterogenous cell clusters through fibrotic niche generation

Sau Yee Kok et al.

Summary: In the liver, malignant subclones induce fibrotic niche generation through hepatic stellate cell activation, supporting the survival and colonization of non-metastatic cells to develop polyclonal metastasis.

NATURE COMMUNICATIONS (2021)

Article Biology

Whole-organ analysis of TGF-β-mediated remodelling of the tumour microenvironment by tissue clearing

Shimpei Kubota et al.

Summary: A study established an integrated pipeline combining tissue clearing, 3D imaging, and machine learning for analysis of the tumour microenvironment in a mouse model of lung tumour, revealing the role of TGF-beta in remodeling the cellular microenvironment to favor metastatic invasion.

COMMUNICATIONS BIOLOGY (2021)

Review Neurosciences

Tissue clearing and its applications in neuroscience

Hiroki R. Ueda et al.

NATURE REVIEWS NEUROSCIENCE (2020)

Article Multidisciplinary Sciences

Versatile whole-organ/body staining and imaging based on electrolyte-gel properties of biological tissues

Etsuo A. Susaki et al.

NATURE COMMUNICATIONS (2020)

Article Biochemical Research Methods

Protocol for Imaging and Analysis of Mouse Tumor Models with CUBIC Tissue Clearing

Kei Takahashi et al.

STAR PROTOCOLS (2020)

Review Oncology

The dormant cancer cell life cycle

Tri Giang Phan et al.

NATURE REVIEWS CANCER (2020)

Review Biochemistry & Molecular Biology

Ki-67: more than a proliferation marker

Xiaoming Sun et al.

CHROMOSOMA (2018)

Article Cell Biology

Chemical Landscape for Tissue Clearing Based on Hydrophilic Reagents

Kazuki Tainaka et al.

CELL REPORTS (2018)

Review Oncology

Intracellular and extracellular TGF-β signaling in cancer: some recent topics

Kohei Miyazono et al.

FRONTIERS OF MEDICINE (2018)

Article Biochemistry & Molecular Biology

Genetically Encoded Tools for Optical Dissection of the Mammalian Cell Cycle

Asako Sakaue-Sawano et al.

MOLECULAR CELL (2017)

Article Cell Biology

Whole-Body Profiling of Cancer Metastasis with Single-Cell Resolution

Shimpei I. Kubota et al.

CELL REPORTS (2017)

Review Oncology

Cell cycle proteins as promising targets in cancer therapy

Tobias Otto et al.

NATURE REVIEWS CANCER (2017)

Article Biochemical Research Methods

Advanced CUBIC protocols for whole-brain and whole-body clearing and imaging

Etsuo A. Susaki et al.

NATURE PROTOCOLS (2015)

Article Biochemistry & Molecular Biology

Whole-Body Imaging with Single-Cell Resolution by Tissue Decolorization

Kazuki Tainaka et al.

Review Oncology

Drug Resistance in Cancer: An Overview

Genevieve Housman et al.

CANCERS (2014)

Article Dermatology

Low-dose 5-fluorouracil induces cell cycle G2 arrest and apoptosis in keloid fibroblasts

L. Huang et al.

BRITISH JOURNAL OF DERMATOLOGY (2010)

Article Biochemistry & Molecular Biology

Visualizing spatiotemporal dynamics of multicellular cell-cycle progression

Asako Sakaue-Sawano et al.