相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。An antitumor peptide RS17-targeted CD47, design, synthesis, and antitumor activity
Xinmin Wang et al.
CANCER MEDICINE (2021)
IgA-Mediated Killing of Tumor Cells by Neutrophils Is Enhanced by CD47-SIRPα Checkpoint Inhibition
Louise W. Treffers et al.
CANCER IMMUNOLOGY RESEARCH (2020)
Advances in Anti-Tumor Treatments Targeting the CD47/SIRPα Axis
Wenting Zhang et al.
FRONTIERS IN IMMUNOLOGY (2020)
The Macrophage Do not eat me' signal, CD47, is a clinically validated cancer immunotherapy target
C. H. Takimoto et al.
ANNALS OF ONCOLOGY (2019)
Glutaminyl cyclase is an enzymatic modifier of the CD47-SIRPα axis and a target for cancer immunotherapy
Meike E. W. Logtenberg et al.
NATURE MEDICINE (2019)
Identification of Glutaminyl Cyclase isoenzyme isoQC as a regulator of SIRPα-CD47 axis
Zhiqiang Wu et al.
CELL RESEARCH (2019)
Potent Fc Receptor Signaling by IgA Leads to Superior Killing of Cancer Cells by Neutrophils Compared to IgG
Arianne M. Brandsma et al.
FRONTIERS IN IMMUNOLOGY (2019)
Immuno-subtyping of breast cancer reveals distinct myeloid cell profiles and immunotherapy resistance mechanisms
Ik Sun Kim et al.
NATURE CELL BIOLOGY (2019)
An engineered human Fc domain that behaves like a pH-toggle switch for ultra-long circulation persistence
Chang-Han Lee et al.
NATURE COMMUNICATIONS (2019)
Myeloid immune-checkpoint inhibition enters the clinical stage
Timo K. van den Berg et al.
NATURE REVIEWS CLINICAL ONCOLOGY (2019)
FcγRIIIb Restricts Antibody-Dependent Destruction of Cancer Cells by Human Neutrophils
Louise W. Treffers et al.
FRONTIERS IN IMMUNOLOGY (2019)
Next generation antibody drugs: pursuit of the 'high-hanging fruit'
Paul J. Carter et al.
NATURE REVIEWS DRUG DISCOVERY (2018)
Fc Effector Function Contributes to the Activity of Human Anti-CTLA-4 Antibodies
Frederick Arce Vargas et al.
CANCER CELL (2018)
Cancer-Cell-Intrinsic Mechanisms Shaping the Tumor Immune Landscape
Max D. Wellenstein et al.
IMMUNITY (2018)
Tribody [(HER2)2xCD16] Is More Effective Than Trastuzumab in Enhancing γδ T Cell and Natural Killer Cell Cytotoxicity Against HER2-Expressing Cancer Cells
Hans H. Oberg et al.
FRONTIERS IN IMMUNOLOGY (2018)
The structure of the human glutaminyl cyclase-SEN177 complex indicates routes for developing new potent inhibitors as possible agents for the treatment of neurological disorders
Cecilia Pozzi et al.
JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY (2018)
Fundamental Mechanisms of Immune Checkpoint Blockade Therapy
Spencer C. Wei et al.
CANCER DISCOVERY (2018)
Macrophage Checkpoint Blockade in Cancer - Back to the Future
Alberto Mantovani et al.
NEW ENGLAND JOURNAL OF MEDICINE (2018)
CD47 Blockade by Hu5F9-G4 and Rituximab in Non-Hodgkin's Lymphoma
Ranjana Advani et al.
NEW ENGLAND JOURNAL OF MEDICINE (2018)
Safety, tolerability and efficacy of the glutaminyl cyclase inhibitor PQ912 in Alzheimer's disease: results of a randomized, double-blind, placebo-controlled phase 2a study
Philip Scheltens et al.
ALZHEIMERS RESEARCH & THERAPY (2018)
Effector mechanisms of IgA antibodies against CD20 include recruitment of myeloid cells for antibody-dependent cell-mediated cytotoxicity and complement-dependent cytotoxicity
Stefan Lohse et al.
BRITISH JOURNAL OF HAEMATOLOGY (2018)
Cancer immunotherapy targeting the CD47/SIRPα axis
Kipp Weiskopf
EUROPEAN JOURNAL OF CANCER (2017)
The CD47-SIRPα signaling axis as an innate immune checkpoint in cancer
Hanke L. Matlung et al.
IMMUNOLOGICAL REVIEWS (2017)
Antibody Distance from the Cell Membrane Regulates Antibody Effector Mechanisms
Kirstie L. S. Cleary et al.
JOURNAL OF IMMUNOLOGY (2017)
Discovery of Potent Human Glutaminyl Cyclase Inhibitors as Anti-Alzheimer's Agents Based on Rational Design
Van-Hai Hoang et al.
JOURNAL OF MEDICINAL CHEMISTRY (2017)
Glutaminyl Cyclase Inhibitor PQ912 Improves Cognition in Mouse Models of Alzheimer's Disease-Studies on Relation to Effective Target Occupancy
Torsten Hoffmann et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2017)
Elements of cancer immunity and the cancer-immune set point
Daniel S. Chen et al.
NATURE (2017)
Antibody Tumor Targeting Is Enhanced by CD27 Agonists through Myeloid Recruitment
Anna H. Turaj et al.
CANCER CELL (2017)
STING Activation Reverses Lymphoma-Mediated Resistance to Antibody Immunotherapy
Lekh N. Dahal et al.
CANCER RESEARCH (2017)
Membrane-Proximal Epitope Facilitates Efficient T Cell Synapse Formation by Anti-FcRH5/CD3 and Is a Requirement for Myeloma Cell Killing
Ji Li et al.
CANCER CELL (2017)
An Anti-EGFR IgA That Displays Improved Pharmacokinetics and Myeloid Effector Cell Engagement In Vivo
Stefan Lohse et al.
CANCER RESEARCH (2016)
Improved in vivo anti-tumor effects of IgA-Her2 antibodies through half-life extension and serum exposure enhancement by FcRn targeting
Saskia Meyer et al.
MABS (2016)
Origin and Role of a Subset of Tumor-Associated Neutrophils with Antigen-Presenting Cell Features in Early-Stage Human Lung Cancer
Sunil Singhal et al.
CANCER CELL (2016)
Velcro Engineering of High Affinity CD47 Ectodomain as Signal Regulatory Protein α(SIRPα) Antagonists That Enhance Antibody-dependent Cellular Phagocytosis
Chia Chi M. Ho et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2015)
Macrophages are critical effectors of antibody therapies for cancer
Kipp Weiskopf et al.
MABS (2015)
The prognostic landscape of genes and infiltrating immune cells across human cancers
Andrew J. Gentles et al.
NATURE MEDICINE (2015)
Cell rigidity and shape override CD47's sell-signaling in phagocytosis by hyperactivating myosin-II
Nisha G. Sosale et al.
BLOOD (2015)
Pre-Clinical Development of a Humanized Anti-CD47 Antibody with Anti-Cancer Therapeutic Potential
Jie Liu et al.
PLOS ONE (2015)
The Interaction Between Signal Regulatory Protein Alpha (SIRPα) and CD47: Structure, Function, and Therapeutic Target
A. Neil Barclay et al.
ANNUAL REVIEW OF IMMUNOLOGY, VOL 32 (2014)
Increasing FcγRIIa affinity of an FcγRIII-optimized anti-EGFR antibody restores neutrophil-mediated cytotoxicity
Stefanie Derer et al.
MABS (2014)
An engineered Fc variant of an IgG eliminates all immune effector functions via structural perturbations
Omid Vafa et al.
METHODS (2014)
IgA EGFR antibodies mediate tumour killing in vivo
Peter Boross et al.
EMBO MOLECULAR MEDICINE (2013)
Properties of mouse and human IgG receptors and their contribution to disease models
Pierre Bruhns
BLOOD (2012)
Crosstalk between Human IgG Isotypes and Murine Effector Cells
Marije B. Overdijk et al.
JOURNAL OF IMMUNOLOGY (2012)
Mouse model recapitulating human Fcγ receptor structural and functional diversity
Patrick Smith et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Therapeutic Antibody Targeting of CD47 Eliminates Human Acute Lymphoblastic Leukemia
Mark P. Chao et al.
CANCER RESEARCH (2011)
CD47-signal regulatory protein-α (SIRPα) interactions form a barrier for antibody-mediated tumor cell destruction
Xi Wen Zhao et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Fc-engineered EGF-R antibodies mediate improved antibody-dependent cellular cytotoxicity (ADCC) against KRAS-mutated tumor cells
Martin Schlaeth et al.
CANCER SCIENCE (2010)
Anti-CD47 Antibody Synergizes with Rituximab to Promote Phagocytosis and Eradicate Non-Hodgkin Lymphoma
Mark P. Chao et al.
CELL (2010)
Human IgG2 Antibodies against Epidermal Growth Factor Receptor Effectively Trigger Antibody-Dependent Cellular Cytotoxicity but, in Contrast to IgG1, Only by Cells of Myeloid Lineage
Tanja Schneider-Merck et al.
JOURNAL OF IMMUNOLOGY (2010)
Functions and molecular mechanisms of the CD47-SIRPα signalling pathway
Takashi Matozaki et al.
TRENDS IN CELL BIOLOGY (2009)
Glutaminyl cyclases from animals and plants: a case of functionally convergent protein evolution
Stephan Schilling et al.
BIOLOGICAL CHEMISTRY (2008)
Effector mechanisms of therapeutic antibodies against ErbB receptors
Matthias Peipp et al.
CURRENT OPINION IN IMMUNOLOGY (2008)
Paired receptor specificity explained by structures of signal regulatory proteins alone and complexed with CD47
Deborah Hatherley et al.
MOLECULAR CELL (2008)
Effector mechanisms of recombinant IgA antibodies against epidermal growth factor receptor
Michael Dechant et al.
JOURNAL OF IMMUNOLOGY (2007)
Negative regulation of phagocytosis in macrophages by the CD47-SHPS-1 system
H Okazawa et al.
JOURNAL OF IMMUNOLOGY (2005)
Substrate specificity of glutaminyl cyclases from plants and animals
S Schilling et al.
BIOLOGICAL CHEMISTRY (2003)