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Pembrolizumab versus Ipilimumab in Advanced Melanoma
Caroline Robert et al.
NEW ENGLAND JOURNAL OF MEDICINE (2015)
Quantification of tumor infiltrating Foxp3+regulatory T cells enables the identification of high-risk patients for developing synchronous cancers over upper aerodigestive tract
Wen-Lun Wang et al.
ORAL ONCOLOGY (2015)
T cell exclusion, immune privilege, and the tumor microenvironment
Johanna A. Joyce et al.
SCIENCE (2015)
Cancer prevention and therapy through the modulation of the tumor microenvironment
Stephanie C. Casey et al.
SEMINARS IN CANCER BIOLOGY (2015)
MicroRNA-885-3p inhibits the growth of HT-29 colon cancer cell xenografts by disrupting angiogenesis via targeting BMPR1A and blocking BMP/Smad/Id1 signaling
F. Xiao et al.
ONCOGENE (2015)
Asporin activates coordinated invasion of scirrhous gastric cancer and cancer-associated fibroblasts
R. Satoyoshi et al.
ONCOGENE (2015)
SOX2 regulates self-renewal and tumorigenicity of stem-like cells of head and neck squamous cell carcinoma
S. H. Lee et al.
BRITISH JOURNAL OF CANCER (2014)
Cbx4 Governs HIF-1α to Potentiate Angiogenesis of Hepatocellular Carcinoma by Its SUMO E3 Ligase Activity
Jie Li et al.
CANCER CELL (2014)
Targeting the c-Met/FZD8 Signaling Axis Eliminates Patient-Derived Cancer Stem-like Cells in Head and Neck Squamous Carcinomas
Shuyang Sun et al.
CANCER RESEARCH (2014)
Metastatic Stem Cells: Sources, Niches, and Vital Pathways
Thordur Oskarsson et al.
CELL STEM CELL (2014)
Tumor-specific CD4+ T cells maintain effector and memory tumor-specific CD8+ T cells
Sarah E. Church et al.
EUROPEAN JOURNAL OF IMMUNOLOGY (2014)
Tumor-Associated Macrophages: From Mechanisms to Therapy
Roy Noy et al.
IMMUNITY (2014)
Treg functional stability and its responsiveness to the microenvironment
Joseph Barbi et al.
IMMUNOLOGICAL REVIEWS (2014)
Prognostic significance of ALDH1A1-positive cancer stem cells in patients with locally advanced, metastasized head and neck squamous cell carcinoma
Xu Qian et al.
JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY (2014)
Fibroblast heterogeneity in the cancer wound
Daniel Oehlund et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2014)
Wnt/β-catenin signalling maintains self-renewal and tumourigenicity of head and neck squamous cell carcinoma stem-like cells by activating Oct4
Sang Hyuk Lee et al.
JOURNAL OF PATHOLOGY (2014)
Antitumor Efficacy of the Anti-Interleukin-6 (IL-6) Antibody Siltuximab in Mouse Xenograft Models of Lung Cancer
Lanxi Song et al.
JOURNAL OF THORACIC ONCOLOGY (2014)
SOX2 controls tumour initiation and cancer stem-cell functions in squamous-cell carcinoma
Soufiane Boumahdi et al.
NATURE (2014)
Self-renewal as a therapeutic target in human colorectal cancer
Antonija Kreso et al.
NATURE MEDICINE (2014)
LRIG1 modulates aggressiveness of head and neck cancers by regulating EGFR-MAPK-SPHK1 signaling and extracellular matrix remodeling
J. J-C Sheu et al.
ONCOGENE (2014)
Macrophages stimulate gastric and colorectal cancer invasion through EGFR Y1086, c-Src, Erk1/2 and Akt phosphorylation and smallGTPase activity
A. P. Cardoso et al.
ONCOGENE (2014)
c-Met pathway promotes self-renewal and tumorigenecity of head and neck squamous cell carcinoma stem-like cell
Young Chang Lim et al.
ORAL ONCOLOGY (2014)
Cancer Immunotherapy Based on Mutation-Specific CD4+T Cells in a Patient with Epithelial Cancer
Eric Tran et al.
SCIENCE (2014)
The cellular and molecular origin of tumor-associated macrophages
Ruth A. Franklin et al.
SCIENCE (2014)
LIF Mediates Proinvasive Activation of Stromal Fibroblasts in Cancer
Jean Albrengues et al.
CELL REPORTS (2014)
Extracellular matrix signatures of human mammary carcinoma identify novel metastasis promoters
Alexandra Naba et al.
ELIFE (2014)
Cancer-associated fibroblasts as another polarized cell type of the tumor microenvironment
Martin Augsten
FRONTIERS IN ONCOLOGY (2014)
Stromal disrupting effects of nab-paclitaxel in pancreatic cancer
R. Alvarez et al.
BRITISH JOURNAL OF CANCER (2013)
STC1 Expression By Cancer-Associated Fibroblasts Drives Metastasis of Colorectal Cancer
Cristina Pena et al.
CANCER RESEARCH (2013)
NK cell-based immunotherapy for malignant diseases
Min Cheng et al.
CELLULAR & MOLECULAR IMMUNOLOGY (2013)
Molecular Pathways: Coexpression of Immune Checkpoint Molecules: Signaling Pathways and Implications for Cancer Immunotherapy
Christopher J. Nirschl et al.
CLINICAL CANCER RESEARCH (2013)
Treg and CTLA-4: Two intertwining pathways to immune tolerance
Lucy S. K. Walker
JOURNAL OF AUTOIMMUNITY (2013)
Susceptibility to cytotoxic T cell lysis of cancer stem cells derived from cervical and head and neck tumor cell lines
Tian Liao et al.
JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY (2013)
Expression of type IV collagen in different histological grades of oral squamous cell carcinoma: An immunohistochemical study
Pankaj Agarwal et al.
JOURNAL OF CANCER RESEARCH AND THERAPEUTICS (2013)
Hepatic stellate cells in liver development, regeneration, and cancer
Chunyue Yin et al.
JOURNAL OF CLINICAL INVESTIGATION (2013)
STAT3 regulates arginase-I in myeloid-derived suppressor cells from cancer patients
David Vasquez-Dunddel et al.
JOURNAL OF CLINICAL INVESTIGATION (2013)
The paracrine effect of cancer-associated fibroblast-induced interleukin-33 regulates the invasiveness of head and neck squamous cell carcinoma
Su-Feng Chen et al.
JOURNAL OF PATHOLOGY (2013)
Mechanotransduction and YAP-dependent matrix remodelling is required for the generation and maintenance of cancer-associated fibroblasts
Fernando Calvo et al.
NATURE CELL BIOLOGY (2013)
Ableson kinases negatively regulate invadopodia function and invasion in head and neck squamous cell carcinoma by inhibiting an HB-EGF autocrine loop
K. E. Hayes et al.
ONCOGENE (2013)
Functional effects of SDF-1α on a CD44+ CXCR4+ squamous cell carcinoma cell line as a model for interactions in the cancer stem cell niche
Anne Faber et al.
ONCOLOGY REPORTS (2013)
SDF-1-CXCR4 axis: Cell trafficking in the cancer stem cell niche of head and neck squamous cell carcinoma
Anne Faber et al.
ONCOLOGY REPORTS (2013)
ALDH1-positive cancer stem-like cells are enriched in nodal metastases of oropharyngeal squamous cell carcinoma independent of HPV status
Xu Qian et al.
ONCOLOGY REPORTS (2013)
The kinship of neutrophils and granulocytic myeloid-derived suppressor cells in cancer: Cousins, siblings or twins?
Sven Brandau et al.
SEMINARS IN CANCER BIOLOGY (2013)
Tumor-associated soluble uPAR-directed endothelial cell motility and tumor angiogenesis
J. S. Rao et al.
ONCOGENESIS (2013)
Accessories to the Crime: Functions of Cells Recruited to the Tumor Microenvironment
Douglas Hanahan et al.
CANCER CELL (2012)
Halofuginone Inhibits the Establishment and Progression of Melanoma Bone Metastases
Patricia Juarez et al.
CANCER RESEARCH (2012)
FREQUENCY OF CELLS EXPRESSING CD44, A HEAD AND NECK CANCER STEM CELL MARKER: CORRELATION WITH TUMOR AGGRESSIVENESS
Benzion Joshua et al.
HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK (2012)
The extracellular matrix: A dynamic niche in cancer progression
Pengfei Lu et al.
JOURNAL OF CELL BIOLOGY (2012)
A Humanized Stromal Bed Is Required for Engraftment of Isolated Human Primary Squamous Cell Carcinoma Cells in Immunocompromised Mice
Girish K. Patel et al.
JOURNAL OF INVESTIGATIVE DERMATOLOGY (2012)
Identification and Characterization of Tumor-Initiating Cells in Human Primary Cutaneous Squamous Cell Carcinoma
Girish K. Patel et al.
JOURNAL OF INVESTIGATIVE DERMATOLOGY (2012)
Cancer-Associated Fibroblasts Induce Matrix Metalloproteinase-Mediated Cetuximab Resistance in Head and Neck Squamous Cell Carcinoma Cells
Ann-Charlotte Johansson et al.
MOLECULAR CANCER RESEARCH (2012)
Tumour micro-environment elicits innate resistance to RAF inhibitors through HGF secretion
Ravid Straussman et al.
NATURE (2012)
PDGF-BB modulates hematopoiesis and tumor angiogenesis by inducing erythropoietin production in stromal cells
Yuan Xue et al.
NATURE MEDICINE (2012)
Safety, Activity, and Immune Correlates of Anti-PD-1 Antibody in Cancer
Suzanne L. Topalian et al.
NEW ENGLAND JOURNAL OF MEDICINE (2012)
Stem cell marker (Nanog) and Stat-3 signaling promote MicroRNA-21 expression and chemoresistance in hyaluronan/CD44-activated head and neck squamous cell carcinoma cells
L. Y. W. Bourguignon et al.
ONCOGENE (2012)
Identification of stromally expressed molecules in the prostate by tag-profiling of cancer-associated fibroblasts, normal fibroblasts and fetal prostate
B. Orr et al.
ONCOGENE (2012)
Myeloid-derived suppressor cells contribute to oral cancer progression in 4NQO-treated mice
M. Chu et al.
ORAL DISEASES (2012)
Interleukin-1-mediated effects of normal oral keratinocytes and head and neck squamous carcinoma cells on extracellular matrix related gene expression in fibroblasts
Malin Hakelius et al.
ORAL ONCOLOGY (2012)
Cetuximab therapy in head and neck cancer: Immune modulation with interleukin-12 and other natural killer cell-activating cytokines
Eric Luedke et al.
SURGERY (2012)
Cancer stem cell definitions and terminology: the devil is in the details
Peter Valent et al.
NATURE REVIEWS CANCER (2012)
The blockade of immune checkpoints in cancer immunotherapy
Drew M. Pardoll
NATURE REVIEWS CANCER (2012)
Coordinated regulation of myeloid cells by tumours
Dmitry I. Gabrilovich et al.
NATURE REVIEWS IMMUNOLOGY (2012)
E-3810 Is a Potent Dual Inhibitor of VEGFR and FGFR that Exerts Antitumor Activity in Multiple Preclinical Models
Ezia Bello et al.
CANCER RESEARCH (2011)
Angiopoietin-1 and -2 Exert Antagonistic Functions in Tumor Angiogenesis, yet Both Induce Lymphangiogenesis
Ernesta Fagiani et al.
CANCER RESEARCH (2011)
EGFR-AKT-Smad Signaling Promotes Formation of Glioma Stem-like Cells and Tumor Angiogenesis by ID3-Driven Cytokine Induction
Xun Jin et al.
CANCER RESEARCH (2011)
Cancer Invasion and the Microenvironment: Plasticity and Reciprocity
Peter Friedl et al.
CELL (2011)
Basic and Therapeutic Aspects of Angiogenesis
Michael Potente et al.
CELL (2011)
Hallmarks of Cancer: The Next Generation
Douglas Hanahan et al.
CELL (2011)
Targeting ALDHbright Human Carcinoma-Initiating Cells with ALDH1A1-Specific CD8+ T Cells
Carmen Visus et al.
CLINICAL CANCER RESEARCH (2011)
IMMUNOREGULATORY PROPERTIES OF CD44+CANCER STEM-LIKE CELLS IN SQUAMOUS CELL CARCINOMA OF THE HEAD AND NECK
Kazuaki Chikamatsu et al.
HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK (2011)
Targeted Inhibition of CD133+ Cells in Oral Cancer Cell Lines
M. Damek-Poprawa et al.
JOURNAL OF DENTAL RESEARCH (2011)
Myeloid-derived suppressor cells in the peripheral blood of cancer patients contain a subset of immature neutrophils with impaired migratory properties
Sven Brandau et al.
JOURNAL OF LEUKOCYTE BIOLOGY (2011)
Cancer immunotherapy comes of age
Ira Mellman et al.
NATURE (2011)
Why don't we get more cancer? A proposed role of the microenvironment in restraining cancer progression
Mina J. Bissell et al.
NATURE MEDICINE (2011)
A review of clinical and histological parameters associated with contralateral neck metastases in oral squamous cell carcinoma
Song Fan et al.
INTERNATIONAL JOURNAL OF ORAL SCIENCE (2011)
Trimodal Glioblastoma Treatment Consisting of Concurrent Radiotherapy, Temozolomide, and the Novel TGF-β Receptor I Kinase Inhibitor LY2109761
Mengxian Zhang et al.
NEOPLASIA (2011)
The molecular biology of head and neck cancer
C. Rene Leemans et al.
NATURE REVIEWS CANCER (2011)
Novel cancer immunotherapy agents with survival benefit: recent successes and next steps
Padmanee Sharma et al.
NATURE REVIEWS CANCER (2011)
CD4+ T-Cell Help in the Tumor Milieu Is Required for Recruitment and Cytolytic Function of CD8+ T Lymphocytes
Rinke Bos et al.
CANCER RESEARCH (2010)
GP369, an FGFR2-IIIb-Specific Antibody, Exhibits Potent Antitumor Activity against Human Cancers Driven by Activated FGFR2 Signaling
Ailin Bai et al.
CANCER RESEARCH (2010)
Macrophage Diversity Enhances Tumor Progression and Metastasis
Bin-Zhi Qian et al.
CELL (2010)
A Subpopulation of CD26+ Cancer Stem Cells with Metastatic Capacity in Human Colorectal Cancer
Roberta Pang et al.
CELL STEM CELL (2010)
SINGLE-MARKER IDENTIFICATION OF HEAD AND NECK SQUAMOUS CELL CARCINOMA CANCER STEM CELLS WITH ALDEHYDE DEHYDROGENASE
Matthew R. Clay et al.
HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK (2010)
Tetrathiomolybdate inhibits head and neck cancer metastasis by decreasing tumor cell motility, invasiveness and by promoting tumor cell anoikis
Pawan Kumar et al.
MOLECULAR CANCER (2010)
Cucurbitacin I Suppressed Stem-Like Property and Enhanced Radiation-Induced Apoptosis in Head and Neck Squamous Carcinoma-Derived CD44+ ALDH1+ Cells
Yi-Wei Chen et al.
MOLECULAR CANCER THERAPEUTICS (2010)
TGF beta signaling in head and neck squamous cell carcinoma
R. A. White et al.
ONCOGENE (2010)
Diverse evolutionary paths to cell adhesion
Monika Abedin et al.
TRENDS IN CELL BIOLOGY (2010)
Microenvironmental regulation of metastasis
Johanna A. Joyce et al.
NATURE REVIEWS CANCER (2009)
In childhood acute lymphoblastic leukemia, blasts at different stages of immunophenotypic maturation have stem cell properties
Christoph le Viseur et al.
CANCER CELL (2008)
Subsets of myeloid-derived suppressor cells in tumor-bearing mice
Je-In Youn et al.
JOURNAL OF IMMUNOLOGY (2008)
Endogenous human microRNAs that suppress breast cancer metastasis
Sohail F. Tavazoie et al.
NATURE (2008)
How regulatory T cells work
Dario A. A. Vignali et al.
NATURE REVIEWS IMMUNOLOGY (2008)
Fibroblast-led collective invasion of carcinoma cells with differing roles for RhoGTPases in leading and following cells
Cedric Gaggioli et al.
NATURE CELL BIOLOGY (2007)
The frequency and suppressor function of CD4+CD25high Foxp3+ T cells in the circulation of patients with squamous cell carcinoma of the head and neck
Laura Strauss et al.
CLINICAL CANCER RESEARCH (2007)
Identification of pancreatic cancer stem cells
Chenwei Li et al.
CANCER RESEARCH (2007)
Prognostic value of tumor-infiltrating CD4+ T-cell subpopulations in head and neck cancers
C Badoual et al.
CLINICAL CANCER RESEARCH (2006)
Headpin: A serpin with endogenous and exogenous suppression of angiogenesis
TD Shellenberger et al.
CANCER RESEARCH (2005)
Crosstalk between tumor and endothelial cells promotes tumor angiogenesis by MAPK activation of Notch signaling
QH Zeng et al.
CANCER CELL (2005)
Neoadjuvant immunotherapy of oral squamous cell carcinoma modulates intratumoral CD4/CD8 ratio and tumor microenvironment:: A multicenter phase II clinical trial
J Tímár et al.
JOURNAL OF CLINICAL ONCOLOGY (2005)
Overexpression of transforming growth factor β1 in head and neck epithelia results in inflammation, angiogenesis, and epithelial hyperproliferation
SL Lu et al.
CANCER RESEARCH (2004)
Angiogenesis in health and disease
P Carmeliet
NATURE MEDICINE (2003)
A molecular signature of metastasis in primary solid tumors
S Ramaswamy et al.
NATURE GENETICS (2003)
CD44: From adhesion molecules to signalling regulators
H Ponta et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2003)
Myofibroblasts and mechano-regulation of connective tissue remodelling
JJ Tomasek et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2002)
Disruption of the myocardial extracellular matrix leads to cardiac dysfunction
HE Kim et al.
JOURNAL OF CLINICAL INVESTIGATION (2000)
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