Innate immune cells in the tumor microenvironment

The tumor immune microenvironment (TIME) is a complex ecosystem that contains adaptive and innate immune cells that have tumor-promoting and anti-tumor effects. There is still much to learn about the diversity, plasticity, and functions of innate immune cells in the TIME and their roles in determining the response to immunotherapies. Experts discuss recent advances in our understanding of their biology in cancer as well as outstanding questions and potential therapeutic avenues.

Automated summary

The tumor immune microenvironment (TIME) is a complex ecosystem that consists of adaptive and innate immune cells with both tumor-promoting and anti-tumor effects. Further research is needed to understand the diversity and functions of innate immune cells in the TIME, and their roles in response to immunotherapies. Experts discuss recent advances in this field and potential therapeutic approaches.