Neuroprotection in Acute Ischemic Stroke: A Brief Review

The goal of effective neuroprotection in acute ischemic stroke remains elusive. Despite decades of experimental preclinical and clinical experience with innumerable agents, no strategy has proven to be beneficial in humans. As endovascular therapies mature and approach the limits of speed and efficacy, neuroprotection will become the next frontier of acute stroke care. This review will briefly summarize the history, preclinical and clinical triumphs and failures, and future directions of cerebral neuroprotection.

Automated summary

Despite decades of experiments and clinical experiences with numerous agents, no neuroprotection strategy has been proven beneficial in humans. With the advancement of endovascular therapies, neuroprotection is set to become the next frontier in acute stroke care.