相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Hybrid modeling frameworks of tumor development and treatment
Ibrahim M. Chamseddine et al.
WILEY INTERDISCIPLINARY REVIEWS-SYSTEMS BIOLOGY AND MEDICINE (2020)
Inferring Tumor Proliferative Organization from Phylogenetic Tree Measures in a Computational Model
Jacob G. Scott et al.
SYSTEMATIC BIOLOGY (2020)
Progress and Opportunities to Advance Clinical Cancer Therapeutics Using Tumor Dynamic Models
Rene Bruno et al.
CLINICAL CANCER RESEARCH (2020)
Prostate-specific antigen dynamics predict individual responses to intermittent androgen deprivation
Renee Brady-Nicholls et al.
NATURE COMMUNICATIONS (2020)
Combining hypoxia-activated prodrugs and radiotherapy in silico: Impact of treatment scheduling and the intra-tumoural oxygen landscape
Sara Hamis et al.
PLOS COMPUTATIONAL BIOLOGY (2020)
Ataxia telangiectasia and Rad3-related inhibitors and cancer therapy: where we stand
Lin Mei et al.
JOURNAL OF HEMATOLOGY & ONCOLOGY (2019)
Mathematical Models of Cancer: When to Predict Novel Therapies, and When Not to
Renee Brady et al.
BULLETIN OF MATHEMATICAL BIOLOGY (2019)
3D tumor spheroids as in vitro models to mimic in vivo human solid tumors resistance to therapeutic drugs
Ana S. Nunes et al.
BIOTECHNOLOGY AND BIOENGINEERING (2019)
PubChem 2019 update: improved access to chemical data
Sunghwan Kim et al.
NUCLEIC ACIDS RESEARCH (2019)
Therapeutic Targeting of the DNA Damage Response Using an ATR Inhibitor in Biliary Tract Cancer
Ah-Rong Nam et al.
CANCER RESEARCH AND TREATMENT (2019)
The 2019 mathematical oncology roadmap
Russell C. Rockne et al.
PHYSICAL BIOLOGY (2019)
Blackboard to Bedside: A Mathematical Modeling Bottom-Up Approach Toward Personalized Cancer Treatments
Sara Hamis et al.
JCO CLINICAL CANCER INFORMATICS (2019)
Systems Biology, Systems Medicine, Systems Pharmacology: The What and The Why
Angelique Stephanou et al.
ACTA BIOTHEORETICA (2018)
Development of Chemotherapy with Cell-Cycle Inhibitors for Adult and Pediatric Cancer Therapy
Christopher C. Mills et al.
CANCER RESEARCH (2018)
Combining radiation with hyperthermia: a multiscale model informed by in vitro experiments
S. Bruningk et al.
JOURNAL OF THE ROYAL SOCIETY INTERFACE (2018)
What does not kill a tumour may make it stronger: In silico insights into chemotherapeutic drug resistance
Sara Hamis et al.
JOURNAL OF THEORETICAL BIOLOGY (2018)
PhysiCell: An open source physics-based cell simulator for 3-D multicellular systems
Ahmadreza Ghaffarizadeh et al.
PLOS COMPUTATIONAL BIOLOGY (2018)
ATR Inhibition Is a Promising Radiosensitizing Strategy for Triple-Negative Breast Cancer
Xinyi Tu et al.
MOLECULAR CANCER THERAPEUTICS (2018)
Discovery and Characterization of AZD6738, a Potent Inhibitor of Ataxia Telangiectasia Mutated and Rad3 Related (ATR) Kinase with Application as an Anticancer Agent
Kevin M. Foote et al.
JOURNAL OF MEDICINAL CHEMISTRY (2018)
Dancing with the DNA damage response: next-generation anti-cancer therapeutic strategies
Anna Minchom et al.
THERAPEUTIC ADVANCES IN MEDICAL ONCOLOGY (2018)
Development and characterization of a human three-dimensional chondrosarcoma culture for in vitro drug testing
Aurelien Voissiere et al.
PLOS ONE (2017)
DNA damage response inhibitors: Mechanisms and potential applications in cancer therapy
Laura Carrassa et al.
CANCER TREATMENT REVIEWS (2017)
Targeting ATR in cancer medicine
Raghav Sundar et al.
CURRENT PROBLEMS IN CANCER (2017)
A Model for Spheroid versus Monolayer Response of SK-N-SH Neuroblastoma Cells to Treatment with 15-Deoxy-PGJ2
Dorothy I. Wallace et al.
COMPUTATIONAL AND MATHEMATICAL METHODS IN MEDICINE (2016)
Hypoxia-activated pro-drug TH-302 exhibits potent tumor suppressive activity and cooperates with chemotherapy against osteosarcoma
Vasilios Liapis et al.
CANCER LETTERS (2015)
TH-302 in Combination with Radiotherapy Enhances the Therapeutic Outcome and Is Associated with Pretreatment [18F]HX4 Hypoxia PET Imaging
Sarah G. J. A. Peeters et al.
CLINICAL CANCER RESEARCH (2015)
Systems oncology: Towards patient-specific treatment regimes informed by multiscale mathematical modelling
Gibin G. Powathil et al.
SEMINARS IN CANCER BIOLOGY (2015)
The orally active and bioavailable ATR kinase inhibitor AZD6738 potentiates the anti-tumor effects of cisplatin to resolve ATM-deficient non-small cell lung cancer in vivo
Frank P. Vendetti et al.
ONCOTARGET (2015)
Bridging the gap between in vitro and in vivo: Dose and schedule predictions for the ATR inhibitor AZD6738
Stephen Checkley et al.
SCIENTIFIC REPORTS (2015)
Agent-Based Modeling in Systems Pharmacology
J. Cosgrove et al.
CPT-PHARMACOMETRICS & SYSTEMS PHARMACOLOGY (2015)
Enabling multiscale modeling in systems medicine
Olaf Wolkenhauer et al.
GENOME MEDICINE (2014)
Implementation of Quantitative and Systems Pharmacology in Large Pharma
S. A. G. Visser et al.
CPT-PHARMACOMETRICS & SYSTEMS PHARMACOLOGY (2014)
Spartan: A Comprehensive Tool for Understanding Uncertainty in Simulations of Biological Systems
Kieran Alden et al.
PLOS COMPUTATIONAL BIOLOGY (2013)
Chaste: An Open Source C plus plus Library for Computational Physiology and Biology
Gary R. Mirams et al.
PLOS COMPUTATIONAL BIOLOGY (2013)
Selective Tumor Hypoxia Targeting by Hypoxia-Activated Prodrug TH-302 Inhibits Tumor Growth in Preclinical Models of Cancer
Jessica D. Sun et al.
CLINICAL CANCER RESEARCH (2012)
Modeling the Spatial Distribution of Chronic Tumor Hypoxia: Implications for Experimental and Clinical Studies
Gibin Powathil et al.
COMPUTATIONAL AND MATHEMATICAL METHODS IN MEDICINE (2012)
Modelling the effects of cell-cycle heterogeneity on the response of a solid tumour to chemotherapy: Biological insights from a hybrid multiscale cellular automaton model
Gibin G. Powathil et al.
JOURNAL OF THEORETICAL BIOLOGY (2012)
Hybrid models of tumor growth
Katarzyna A. Rejniak et al.
WILEY INTERDISCIPLINARY REVIEWS-SYSTEMS BIOLOGY AND MEDICINE (2011)
Targeting the multiple myeloma hypoxic niche with TH-302, a hypoxia-activated prodrug
Jinsong Hu et al.
BLOOD (2010)
A mathematical model of the effects of hypoxia on the cell-cycle of normal and cancer cells
T Alarcón et al.
JOURNAL OF THEORETICAL BIOLOGY (2004)
A model for restriction point control of the mammalian cell cycle
M Novák et al.
JOURNAL OF THEORETICAL BIOLOGY (2004)
Regulation of the eukaryotic cell cycle: Molecular antagonism, hysteresis, and irreversible transitions
JJ Tyson et al.
JOURNAL OF THEORETICAL BIOLOGY (2001)
分享论文
