期刊
BRIEFINGS IN BIOINFORMATICS
卷 22, 期 6, 页码 -出版社
OXFORD UNIV PRESS
DOI: 10.1093/bib/bbab205
关键词
antimicrobial peptides; natural products; medicinal plant; essential oils; natural active substances; database
资金
- National Natural Science Foundation of China [21772059, 91853127, 31960548]
- Program of Introducing Talents of Discipline to Universities of China (111 Program) [D20023]
- Frontiers Science Center for Asymmetric Synthesis and Medicinal Molecules, Department of Education, Guizhou Province [(2020)004]
This study investigated online resources related to insecticides, antimicrobials, medicinal plants, and plant essential oils, showcasing their functionalities, data sources, and applicability. The research also discussed limitations of these resources, providing a valuable toolbox for scientists.
The grand challenge to meet the increasing demands for food by a rapidly growing global population requires protecting crops from pests. Natural active substances play a significant role in the sustainable pests and pathogenic microbes management. In recent years, natural products- (NPs), antimicrobial peptides- (AMPs), medicinal plant- and plant essential oils (EOs)-related online resources have greatly facilitated the development of pests and pathogenic microbes control agents in an efficient and economical manner. However, a comprehensive comparison, analysis and summary of these existing web resources are still lacking. Here, we surveyed these databases of NPs, AMPs, medicinal plants and plant EOs with insecticidal, antibacterial, antiviral and antifungal activity, and we compared their functionality, data volume, data sources and applicability. We comprehensively discussed the limitation of these web resources. This study provides a toolbox for bench scientists working in the pesticide, botany, biomedical and pharmaceutical engineering fields. The aim of the review is to hope that these web resources will facilitate the discovery and development of potential active ingredients of pests and pathogenic microbes control agents.
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