期刊
BREAST
卷 57, 期 -, 页码 113-117出版社
CHURCHILL LIVINGSTONE
DOI: 10.1016/j.breast.2021.03.008
关键词
Targeted axillary dissection; Targeted lymph node biopsy; Magnetic marker
Magseed (R) is a reliable and feasible marker for identifying TLNs in breast cancer patients, significantly improving the identification rate of sentinel lymph node biopsy.
Background: Targeted axillary dissection (TAD), the combination of sentinel lymph node biopsy (SLNB) and targeted lymph node biopsy (TLNB), can reduce the false negative rates of sentinel node biopsy alone dramatically in breast cancer patients, who received neoadjuvant chemotherapy (NAC). However methods for TAD are still under investigation. Methods: Magseed (R), a non-radioactive magnetic marker was used to mark the biopsied positive TLN after NAC. The SLNB with the standard technetium-based method and the selective TLNB with Magseed (R) localization were performed in 40 patients. The TLNs were identified with the Sentimag (R) probe and excised in all patients. Specimen x-ray was performed to confirm the Magseed (R) within the prior to NAC biopsied and clipped lymph node. Results: The TLN identification rate was 100% (40/40), the SLN identification rate was 82.5% (33/40), the concordance rate between the TLN and the SLN was 65% (26/40). Complications according Magseed (R) deployment or identification could not be observed. Conclusion: Magseed (R) is a reliable and feasible marker for the identification of TLNs after NAC. (c) 2021 The Author(s). Published by Elsevier Ltd. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
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