4.6 Article

A positive-feedback loop between HBx and ALKBH5 promotes hepatocellular carcinogenesis

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Gastroenterology & Hepatology

HBV-Induced Increased N6 Methyladenosine Modification of PTEN RNA Affects Innate Immunity and Contributes to HCC

Geon-Woo Kim et al.

Summary: HBV significantly increases m(6)A modification of PTEN RNA, leading to a decrease in PTEN protein levels and affecting IRF-3 function and interferon synthesis. This finding provides new insights into HBV-mediated immune evasion and HBV-associated hepatocarcinogenesis.

HEPATOLOGY (2021)

Article Multidisciplinary Sciences

Landscape of oncoviral genotype and co-infection via human papilloma and hepatitis B viral tumor in situ profiling

Adrian Bubie et al.

Summary: The role of oncoviral genotype and co-infection in oncogenesis is still unclear, but studies have shown that HBV and HPV genotype and co-infection can significantly predict patient survival and immune activation, with HPV genotype being more associated with viral oncogene expression. This research helps to reveal mechanisms of oncogenesis and clinical associations.

ISCIENCE (2021)

Review Biochemistry & Molecular Biology

The emerging roles of N6-methyladenosine (m6A) deregulation in liver carcinogenesis

Mengnuo Chen et al.

MOLECULAR CANCER (2020)

Review Gastroenterology & Hepatology

Epitranscriptomics in liver disease: Basic concepts and therapeutic potential

Zhicong Zhao et al.

JOURNAL OF HEPATOLOGY (2020)

Review Oncology

The biological function of m6A demethylase ALKBH5 and its role in human disease

Jinyan Wang et al.

CANCER CELL INTERNATIONAL (2020)

Article Biochemistry & Molecular Biology

ALKBH5 suppresses malignancy of hepatocellular carcinoma via m6A-guided epigenetic inhibition of LYPD1

Yunhao Chen et al.

MOLECULAR CANCER (2020)

Article Endocrinology & Metabolism

Hepatic FTO is dispensable for the regulation of metabolism but counteracts HCC development in vivo

Melanie J. Mittenbuhler et al.

MOLECULAR METABOLISM (2020)

Article Gastroenterology & Hepatology

Global liver disease burdens and research trends: Analysis from a Chinese perspective

Jia Xiao et al.

JOURNAL OF HEPATOLOGY (2019)

Review Cell Biology

Reading, writing and erasing mRNA methylation

Sara Zaccara et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2019)

Review Cell Biology

Reading, writing and erasing mRNA methylation

Sara Zaccara et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2019)

Review Genetics & Heredity

Chemical Modifications in the Life of an mRNA Transcript

Sigrid Nachtergaele et al.

ANNUAL REVIEW OF GENETICS, VOL 52 (2018)

Article Multidisciplinary Sciences

N6-methyladenosine modification of hepatitis B virus RNA differentially regulates the viral life cycle

Hasan Imam et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2018)

Review Multidisciplinary Sciences

Epigenetic plasticity and the hallmarks of cancer

William A. Flavahan et al.

SCIENCE (2017)

Review Multidisciplinary Sciences

The cancer epigenome: Concepts, challenges, and therapeutic opportunities

Mark A. Dawson

SCIENCE (2017)

Article Biochemistry & Molecular Biology

Comprehensive and Integrative Genomic Characterization of Hepatocellular Carcinoma

Adrian Ally et al.

Review Gastroenterology & Hepatology

Mechanisms of HBV-induced hepatocellular carcinoma

Massimo Levrero et al.

JOURNAL OF HEPATOLOGY (2016)

Article Medicine, Research & Experimental

Hepatitis B Virus Genotypes and Variants

Chih-Lin Lin et al.

COLD SPRING HARBOR PERSPECTIVES IN MEDICINE (2015)

Review Biochemistry & Molecular Biology

Mechanism and Function of Oxidative Reversal of DNA and RNA Methylation

Li Shen et al.

ANNUAL REVIEW OF BIOCHEMISTRY, VOL 83 (2014)

Article Biochemistry & Molecular Biology

High-resolution profiling of histone methylations in the human genome

Artern Barski et al.