4.8 Article

A portable triboelectric spirometer for wireless pulmonary function monitoring

期刊

BIOSENSORS & BIOELECTRONICS
卷 187, 期 -, 页码 -

出版社

ELSEVIER ADVANCED TECHNOLOGY
DOI: 10.1016/j.bios.2021.113329

关键词

COVID-19; Self-powered sensors; Triboelectric nanogenerators; Spirometers; Pulmonary function tests

资金

  1. National Natural Science Foundation of China [61974071, 61601394]
  2. National Key Research and Development Program of China [2017YFA0205302]
  3. Priority Academic Program Development of Jiangsu Higher Education Institutions (PAPD) [YX030003]
  4. Jiangsu Provincial Key Research and Development Program [BE2018732]
  5. Jiangsu Shuangchuang Talent Program
  6. Nanjing University of Posts and Telecommunications [NY218151, NY218157]
  7. Henry Samueli School of Engineering AMP
  8. Applied Science
  9. 2020 Okawa Foundation Research Grant
  10. Department of Bioengineering at the University of California, Los Angeles
  11. Science and Technology Innovation Project for Overseas Students in Nanjing

向作者/读者索取更多资源

The article introduces a wireless, portable pulmonary function monitor for rehabilitation care after COVID-19. It utilizes a breath-to-electrical sensor to convert respiratory biomechanical motions into electrical signals, which are then transmitted to a mobile terminal via a Bluetooth communication unit for processing important physiological parameters such as FEV1/FVC ratio.
Coronavirus disease 2019 (COVID-19) as a severe acute respiratory syndrome infection has spread rapidly across the world since its emergence in 2019 and drastically altered our way of life. Patients who have recovered from COVID-19 may still face persisting respiratory damage from the virus, necessitating long-term supervision after discharge to closely assess pulmonary function during rehabilitation. Therefore, developing portable spirometers for pulmonary function tests is of great significance for convenient home-based monitoring during recovery. Here, we propose a wireless, portable pulmonary function monitor for rehabilitation care after COVID-19. It is composed of a breath-to-electrical (BTE) sensor, a signal processing circuit, and a Bluetooth communication unit. The BTE sensor, with a compact size and light weight of 2.5 cm3 and 1.8 g respectively, is capable of converting respiratory biomechanical motions into considerable electrical signals. The output signal stability is greater than 93% under 35%-81% humidity, which allows for ideal expiration airflow sensing. Through a wireless communication circuit system, the signals can be received by a mobile terminal and processed into important physiological parameters, such as forced expiratory volume in 1 s (FEV1) and forced vital capacity (FVC). The FEV1/FVC ratio is then calculated to further evaluate pulmonary function of testers. Through these measurement methods, the acquired pulmonary function parameters are shown to exhibit high accuracy (>97%) in comparison to a commercial spirometer. The practical design of the self-powered flow spirometer presents a low-cost and convenient method for pulmonary function monitoring during rehabilitation from COVID-19.

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