期刊
BIOSENSORS & BIOELECTRONICS
卷 187, 期 -, 页码 -出版社
ELSEVIER ADVANCED TECHNOLOGY
DOI: 10.1016/j.bios.2021.113329
关键词
COVID-19; Self-powered sensors; Triboelectric nanogenerators; Spirometers; Pulmonary function tests
类别
资金
- National Natural Science Foundation of China [61974071, 61601394]
- National Key Research and Development Program of China [2017YFA0205302]
- Priority Academic Program Development of Jiangsu Higher Education Institutions (PAPD) [YX030003]
- Jiangsu Provincial Key Research and Development Program [BE2018732]
- Jiangsu Shuangchuang Talent Program
- Nanjing University of Posts and Telecommunications [NY218151, NY218157]
- Henry Samueli School of Engineering AMP
- Applied Science
- 2020 Okawa Foundation Research Grant
- Department of Bioengineering at the University of California, Los Angeles
- Science and Technology Innovation Project for Overseas Students in Nanjing
The article introduces a wireless, portable pulmonary function monitor for rehabilitation care after COVID-19. It utilizes a breath-to-electrical sensor to convert respiratory biomechanical motions into electrical signals, which are then transmitted to a mobile terminal via a Bluetooth communication unit for processing important physiological parameters such as FEV1/FVC ratio.
Coronavirus disease 2019 (COVID-19) as a severe acute respiratory syndrome infection has spread rapidly across the world since its emergence in 2019 and drastically altered our way of life. Patients who have recovered from COVID-19 may still face persisting respiratory damage from the virus, necessitating long-term supervision after discharge to closely assess pulmonary function during rehabilitation. Therefore, developing portable spirometers for pulmonary function tests is of great significance for convenient home-based monitoring during recovery. Here, we propose a wireless, portable pulmonary function monitor for rehabilitation care after COVID-19. It is composed of a breath-to-electrical (BTE) sensor, a signal processing circuit, and a Bluetooth communication unit. The BTE sensor, with a compact size and light weight of 2.5 cm3 and 1.8 g respectively, is capable of converting respiratory biomechanical motions into considerable electrical signals. The output signal stability is greater than 93% under 35%-81% humidity, which allows for ideal expiration airflow sensing. Through a wireless communication circuit system, the signals can be received by a mobile terminal and processed into important physiological parameters, such as forced expiratory volume in 1 s (FEV1) and forced vital capacity (FVC). The FEV1/FVC ratio is then calculated to further evaluate pulmonary function of testers. Through these measurement methods, the acquired pulmonary function parameters are shown to exhibit high accuracy (>97%) in comparison to a commercial spirometer. The practical design of the self-powered flow spirometer presents a low-cost and convenient method for pulmonary function monitoring during rehabilitation from COVID-19.
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