4.8 Article

A novel organ-chip system emulates three-dimensional architecture of the human epithelia and the mechanical forces acting on it

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Review Pharmacology & Pharmacy

Organ-on-a-Chip: A New Paradigm for Drug Development

Chao Ma et al.

Summary: Organ-on-a-Chip technology has the potential to revolutionize drug development by mimicking the physiological environment and function of human organs on a chip. However, challenges remain in translating and commercializing this technology for pharmacological and medical applications.

TRENDS IN PHARMACOLOGICAL SCIENCES (2021)

Review Biotechnology & Applied Microbiology

Advances in Engineering Human Tissue Models

Chrysanthi-Maria Moysidou et al.

Summary: Research in cell biology heavily relies on in vitro assays and models, with the recent advancement in 3D cell biology and engineering providing more physiologically relevant culture platforms. These platforms, such as scaffold-based systems and organs-on-chips, show great potential in bridging the gap between conventional animal studies and human physiology by allowing for more accurate modeling of specific processes.

FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY (2021)

Article Biology

Second-generation lung-on-a-chip with an array of stretchable alveoli made with a biological membrane

Pauline Zamprogno et al.

Summary: A new generation lung-on-a-chip utilizing a biological membrane made of collagen and elastin has been developed to mimic an array of tiny alveoli with in vivo-like dimensions. This membrane outperforms traditional PDMS in terms of stability, biodegradability, and tunability, offering the potential to more accurately reproduce air-blood barrier functions.

COMMUNICATIONS BIOLOGY (2021)

Article Biochemistry & Molecular Biology

A Microengineered Airway Lung Chip Models Key Features of Viral-induced Exacerbation of Asthma

Janna C. Nawroth et al.

AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2020)

Article Engineering, Electrical & Electronic

Microfluidic platforms for cell cultures and investigations

Maria Laura Coluccio et al.

MICROELECTRONIC ENGINEERING (2019)

Article Cell Biology

Reproducing human and cross-species drug toxicities using a Liver-Chip

Kyung-Jin Jang et al.

SCIENCE TRANSLATIONAL MEDICINE (2019)

Review Chemistry, Analytical

Methods of Delivering Mechanical Stimuli to Organ-on-a-Chip

Kattika Kaarj et al.

MICROMACHINES (2019)

Review Cell & Tissue Engineering

Microfluidic three-dimensional cell culture of stem cells for high-throughput analysis

Jeong Ah Kim et al.

WORLD JOURNAL OF STEM CELLS (2019)

Review Cell & Tissue Engineering

Three-dimensional cell culture systems as an in vitro platform for cancer and stem cell modeling

Nipha Chaicharoenaudomrung et al.

WORLD JOURNAL OF STEM CELLS (2019)

Review Engineering, Biomedical

Recent advances in biomaterials for 3D scaffolds: A review

Maria P. Nikolova et al.

BIOACTIVE MATERIALS (2019)

Article Engineering, Biomedical

Epithelial-mesenchymal crosstalk influences cellular behavior in a 3D alveolus-fibroblast model system

Katherine J. R. Lewis et al.

BIOMATERIALS (2018)

Review Cell & Tissue Engineering

Organs-on-a-Chip: A Fast Track for Engineered Human Tissues in Drug Development

Kacey Ronaldson-Bouchard et al.

CELL STEM CELL (2018)

Article Materials Science, Multidisciplinary

Full-thickness human skin-on-chip with enhanced epidermal morphogenesis and barrier function

Gopu Sriram et al.

MATERIALS TODAY (2018)

Review Pharmacology & Pharmacy

Three-Dimensional in Vitro Cell Culture Models in Drug Discovery and Drug Repositioning

Sigrid A. Langhans

FRONTIERS IN PHARMACOLOGY (2018)

Review Nanoscience & Nanotechnology

Extracellular matrix-based materials for regenerative medicine

George S. Hussey et al.

NATURE REVIEWS MATERIALS (2018)

Review Multidisciplinary Sciences

Flat and microstructured polymeric membranes in organs-on-chips

Thijs Pasman et al.

JOURNAL OF THE ROYAL SOCIETY INTERFACE (2018)

Review Pharmacology & Pharmacy

Human-derived Organ-on-a-Chip for Personalized Drug Development

Yasamin A. Jodat et al.

CURRENT PHARMACEUTICAL DESIGN (2018)

Article Multidisciplinary Sciences

Development of a primary human Small Intestine-on-a-Chip using biopsy-derived organoids

Magdalena Kasendra et al.

SCIENTIFIC REPORTS (2018)

Article Multidisciplinary Sciences

Medium throughput breathing human primary cell alveolus-on-chip model

Janick D. Stucki et al.

SCIENTIFIC REPORTS (2018)

Article Multidisciplinary Sciences

Scalable Fabrication of Stretchable, Dual Channel, Microfluidic Organ Chips

Richard Novak et al.

JOVE-JOURNAL OF VISUALIZED EXPERIMENTS (2018)

Article Engineering, Biomedical

Perspective: The promise of multi-cellular engineered living systems

Roger D. Kamm et al.

APL BIOENGINEERING (2018)

Article Biology

Characterization of air-liquid interface culture of A549 alveolar epithelial cells

J. Wu et al.

BRAZILIAN JOURNAL OF MEDICAL AND BIOLOGICAL RESEARCH (2018)

Review Physiology

Modeling Physiological Events in 2D vs. 3D Cell Culture

Kayla Duval et al.

PHYSIOLOGY (2017)

Article Biochemical Research Methods

Three-Dimensional Cell Cultures in Drug Discovery and Development

Ye Fang et al.

SLAS DISCOVERY (2017)

Article Biochemical Research Methods

Small airway-on-a-chip enables analysis of human lung inflammation and drug responses in vitro

Kambez H. Benam et al.

NATURE METHODS (2016)

Review Polymer Science

Advancing biomaterials of human origin for tissue engineering

Fa-Ming Chen et al.

PROGRESS IN POLYMER SCIENCE (2016)

Review Cell & Tissue Engineering

Hydrogel microfabrication technology toward three dimensional tissue engineering

Fumiki Yanagawa et al.

REGENERATIVE THERAPY (2016)

Article Multidisciplinary Sciences

Skin-on-a-chip model simulating inflammation, edema and drug-based treatment

Maierdanjiang Wufuer et al.

SCIENTIFIC REPORTS (2016)

Article Biochemical Research Methods

Pumpless microfluidic platform for drug testing on human skin equivalents

Hasan Erbil Abaci et al.

LAB ON A CHIP (2015)

Review Cell Biology

Microfluidics: reframing biological enquiry

Todd A. Duncombe et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2015)

Article Engineering, Biomedical

Extracellular Matrix as a Driver for Lung Regeneration

Jenna L. Balestrini et al.

ANNALS OF BIOMEDICAL ENGINEERING (2015)

Review Biochemical Research Methods

Biomimetic 3D Tissue Models for Advanced High-Throughput Drug Screening

Ki-Hwan Nam et al.

Review Biochemical Research Methods

Three-Dimensional Cell Culture Systems and Their Applications in Drug Discovery and Cell-Based Biosensors

Rasheena Edmondson et al.

ASSAY AND DRUG DEVELOPMENT TECHNOLOGIES (2014)

Article Biotechnology & Applied Microbiology

Keratinization induced by air exposure in the reconstructed human epidermal model: An in vitro model of a cultured epithelial autograft

Takao Hanada et al.

JOURNAL OF BIOSCIENCE AND BIOENGINEERING (2014)

Review Cell Biology

Three-dimensional organotypic culture: experimental models of mammalian biology and disease

Eliah R. Shamir et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2014)

Review Biotechnology & Applied Microbiology

Cell Microenvironment Engineering and Monitoring for Tissue Engineering and Regenerative Medicine: The Recent Advances

Julien Barthes et al.

BIOMED RESEARCH INTERNATIONAL (2014)

Article Biochemical Research Methods

Microfabrication of human organs-on-chips

Dongeun Huh et al.

NATURE PROTOCOLS (2013)

Review Biochemical Research Methods

Microfluidic 3D cell culture: potential application for tissue-based bioassays

XiuJun (James) Li et al.

BIOANALYSIS (2012)

Article Multidisciplinary Sciences

Generation of Organotypic Raft Cultures from Primary Human Keratinocytes

Daniel Anacker et al.

JOVE-JOURNAL OF VISUALIZED EXPERIMENTS (2012)

Article Physiology

The air-liquid interface and use of primary cell cultures are important to recapitulate the transcriptional profile of in vivo airway epithelia

Alejandro A. Pezzulo et al.

AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2011)

Review Cell Biology

From 3D cell culture to organs-on-chips

Dongeun Huh et al.

TRENDS IN CELL BIOLOGY (2011)

Article Respiratory System

Alveolar fibroblasts in acute lung injury: biological behaviour and clinical relevance

C. Quesnel et al.

EUROPEAN RESPIRATORY JOURNAL (2010)

Review Biotechnology & Applied Microbiology

Engineering hydrogels as extracellular matrix mimics

Hikmet Geckil et al.

NANOMEDICINE (2010)

Article Physiology

Variable stretch pattern enhances surfactant secretion in alveolar type II cells in culture

Stephen P. Arold et al.

AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2009)

Review Biochemistry & Molecular Biology

Hug Tightly and Say Goodbye: Role of Endothelial ICAM-1 in Leukocyte Transmigration

Arshad Rahman et al.

ANTIOXIDANTS & REDOX SIGNALING (2009)

Article Biotechnology & Applied Microbiology

Hydrogels as Extracellular Matrix Mimics for 3D Cell Culture

Mark W. Tibbitt et al.

BIOTECHNOLOGY AND BIOENGINEERING (2009)

Review Genetics & Heredity

Modelling tissues in 3D: the next future of pharmaco-toxicology and food research?

Giovanna Mazzoleni et al.

GENES AND NUTRITION (2009)

Article Physiology

Atomic force microscope elastography reveals phenotypic differences in alveolar cell stiffness

Evren U. Azeloglu et al.

JOURNAL OF APPLIED PHYSIOLOGY (2008)

Review Multidisciplinary Sciences

Natural origin biodegradable systems in tissue engineering and regenerative medicine: present status and some moving trends

J. F. Mano et al.

JOURNAL OF THE ROYAL SOCIETY INTERFACE (2007)

Article Respiratory System

Role of alveolar epithelial ICAM-1 in lipopolysaccharide-induced lung inflammation

B Beck-Schimmer et al.

EUROPEAN RESPIRATORY JOURNAL (2002)

Article Physiology

Mechanical stretch promotes alveolar epithelial type II cell differentiation

J Sanchez-Esteban et al.

JOURNAL OF APPLIED PHYSIOLOGY (2001)