4.7 Article

UCSCXenaShiny: an R/CRAN package for interactive analysis of UCSC Xena data

期刊

BIOINFORMATICS
卷 38, 期 2, 页码 527-529

出版社

OXFORD UNIV PRESS
DOI: 10.1093/bioinformatics/btab561

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资金

  1. National Natural Science Foundation of China [31771373, 81472594, 81770781]
  2. Shanghai Science and Technology Commission [21ZR1442400]
  3. ShanghaiTech University

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UCSC Xena platform offers processed cancer omics data, while UCSCXenaShiny is an R Shiny package that allows users to quickly search, download, and explore the data. This tool provides important research opportunities for cancer researchers and clinicians with limited programming experience.
UCSC Xena platform provides huge amounts of processed cancer omics data from large cancer research projects (e.g. TCGA, CCLE and PCAWG) or individual research groups and enables unprecedented research opportunities. However, a graphical user interface-based tool for interactively analyzing UCSC Xena data and generating elegant plots is still lacking, especially for cancer researchers and clinicians with limited programming experience. Here, we present UCSCXenaShiny, an R Shiny package for quickly searching, downloading, exploring, analyzing and visualizing data from UCSC Xena data hubs. This tool could effectively promote the practical use of public data, and can serve as an important complement to the current Xena genomics explorer.

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