4.7 Article

Tysserand-fast and accurate reconstruction of spatial networks from bioimages

期刊

BIOINFORMATICS
卷 37, 期 21, 页码 3989-3991

出版社

OXFORD UNIV PRESS
DOI: 10.1093/bioinformatics/btab490

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  1. INSERM
  2. Fondation Toulouse Cancer Sante
  3. Pierre Fabre Research Institute as part of the Chair of Bioinformatics in Oncology of the CRCT

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tysserand is a Python library designed to reconstruct spatial networks from spatially resolved omics experiments. It serves as a common tool for the bioinformatics community, allowing for the integration of multiple methods, parameter selection, network cleaning, and data transfer to other libraries.
Networks provide a powerful framework to analyze spatial omics experiments. However, we lack tools that integrate several methods to easily reconstruct networks for further analyses with dedicated libraries. In addition, choosing the appropriate method and parameters can be challenging. We propose tysserand, a Python library to reconstruct spatial networks from spatially resolved omics experiments. It is intended as a common tool to which the bioinformatics community can add new methods to reconstruct networks, choose appropriate parameters, clean resulting networks and pipe data to other libraries.

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