NaViA: a program for the visual analysis of complex mass spectra

Motivation: Native mass spectrometry is now a well-established method for the investigation of protein complexes, specifically their subunit stoichiometry and ligand binding properties. Recent advances allowing the analysis of complex mixtures lead to an increasing diversity and complexity in the spectra obtained. These spectra can be timeconsuming to tackle through manual assignment and challenging for automated approaches. Results: Native Mass Spectrometry Visual Analyser is a web-based tool to augment the manual process of peak assignment. In addition to matching masses to the stoichiometry of its component subunits, it allows raw data processing, assignment and annotation and permits mass spectra to be shared with their respective interpretation.

Automated summary

Native mass spectrometry is a well-established method for studying protein complexes, with recent advancements leading to more diverse and complex spectral data. The Native Mass Spectrometry Visual Analyser is a web-based tool that aids in peak assignment and facilitates data processing and interpretation sharing.