相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Synaptic basis of Alzheimer's disease: Focus on synaptic amyloid beta, P-tau and mitochondria
Albin John et al.
AGEING RESEARCH REVIEWS (2021)
Age-Related Chronic Diseases and Alzheimer's Disease in Texas: A Hispanic Focused Study
Shyam Sheladia et al.
JOURNAL OF ALZHEIMERS DISEASE REPORTS (2021)
Considerations for future tau-targeted therapeutics: can they deliver?
Wendy Noble et al.
EXPERT OPINION ON DRUG DISCOVERY (2020)
Improved Accuracy for Modeling PROTAC-Mediated Ternary Complex Formation and Targeted Protein Degradation via New In Silico Methodologies
Michael L. Drummond et al.
JOURNAL OF CHEMICAL INFORMATION AND MODELING (2020)
Tauopathies: Deciphering Disease Mechanisms to Develop Effective Therapies
M. Catarina Silva et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)
Treatment of Alzheimer’s by PROTAC-Tau Protein Degradation
Robert B. Kargbo
ACS Medicinal Chemistry Letters (2019)
Structure Based Design and Molecular Docking Studies for Phosphorylated Tau Inhibitors in Alzheimer's Disease
Jangampalli Adi Pradeepkiran et al.
CELLS (2019)
Targeted degradation of aberrant tau in frontotemporal dementia patient-derived neuronal cell models
M. Catarina Silva et al.
ELIFE (2019)
Can Healthy Diets, Regular Exercise, and Better Lifestyle Delay the Progression of Dementia in Elderly Individuals?
Elizabeth Kurudamannil George et al.
JOURNAL OF ALZHEIMERS DISEASE (2019)
PROTACs: great opportunities for academia and industry
Xiuyun Sun et al.
SIGNAL TRANSDUCTION AND TARGETED THERAPY (2019)
Tau-targeting therapies for Alzheimer disease
Erin E. Congdon et al.
NATURE REVIEWS NEUROLOGY (2018)
Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs
Sainan An et al.
EBIOMEDICINE (2018)
A Tale of the Good and Bad: Remodeling of the Microtubule Network in the Brain by Cdk5
Kavita Shah et al.
MOLECULAR NEUROBIOLOGY (2017)
Amyloid-Beta and Phosphorylated Tau Accumulations Cause Abnormalities at Synapses of Alzheimer's disease Neurons
Ravi Rajmohan et al.
JOURNAL OF ALZHEIMERS DISEASE (2017)
Amplitude Normalization of Dendritic EPSPs at the Soma of Binaural Coincidence Detector Neurons of the Medial Superior Olive
Bradley D. Winters et al.
JOURNAL OF NEUROSCIENCE (2017)
Synaptic Impairment in Alzheimer's Disease: A Dysregulated Symphony
Stefania Forner et al.
TRENDS IN NEUROSCIENCES (2017)
A Brief Overview of Tauopathy: Causes, Consequences, and Therapeutic Strategies
Miranda E. Orr et al.
TRENDS IN PHARMACOLOGICAL SCIENCES (2017)
Synergistic interaction between amyloid and tau predicts the progression to dementia
Tharick A. Pascoal et al.
ALZHEIMERS & DEMENTIA (2017)
An evolutionary roadmap to the microtubule-associated protein MAP Tau
Frederik Suendermann et al.
BMC GENOMICS (2016)
Special issue on 'Cytoskeletal proteins in health and neurodegenerative disease'
Roland Brandt et al.
BRAIN RESEARCH BULLETIN (2016)
Microtubule plus-end tracking proteins in neuronal development
Dieudonnee van de Willige et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2016)
Dynamic Protein Interaction Networks and New Structural Paradigms in Signaling
Veronika Csizmok et al.
CHEMICAL REVIEWS (2016)
Collapsin Response Mediator Protein-2 (CRMP2) is a Plausible Etiological Factor and Potential Therapeutic Target in Alzheimer's Disease: Comparison and Contrast with Microtubule-Associated Protein Tau
Kenneth Hensley et al.
JOURNAL OF ALZHEIMERS DISEASE (2016)
Tau physiology and pathomechanisms in frontotemporal lobar degeneration
Liviu-Gabriel Bodea et al.
JOURNAL OF NEUROCHEMISTRY (2016)
Epigenetics of dementia: understanding the disease as a transformation rather than a state
Bryan Maloney et al.
LANCET NEUROLOGY (2016)
Presence of a carboxy-terminal pseudorepeat and disease-like pseudohyperphosphorylation critically influence tau's interaction with microtubules in axon-like processes
Benedikt Niewidok et al.
MOLECULAR BIOLOGY OF THE CELL (2016)
Alzheimer disease: modeling an Aβ-centered biological network
D. Campion et al.
MOLECULAR PSYCHIATRY (2016)
High-resolution arrays reveal burden of copy number variations on Parkinson disease genes associated with increased disease risk in random cohorts
Megha N. Murthy et al.
NEUROLOGICAL RESEARCH (2016)
Tau Structures
Jesus Avila et al.
FRONTIERS IN AGING NEUROSCIENCE (2016)
Tau-Centric Targets and Drugs in Clinical Development for the Treatment of Alzheimer's Disease
Francesco Panza et al.
BIOMED RESEARCH INTERNATIONAL (2016)
Axon Initial Segment Cytoskeleton: Architecture, Development, and Role in Neuron Polarity
Steven L. Jones et al.
NEURAL PLASTICITY (2016)
Mechanical Effects of Dynamic Binding between Tau Proteins on Microtubules during Axonal Injury
Hossein Ahmadzadeh et al.
BIOPHYSICAL JOURNAL (2015)
Role of Environmental Contaminants in the Etiology of Alzheimer's Disease: A Review
Manivannan Yegambaram et al.
CURRENT ALZHEIMER RESEARCH (2015)
Tau regulates the localization and function of End-binding proteins 1 and 3 in developing neuronal cells
Carmen Laura Sayas et al.
JOURNAL OF NEUROCHEMISTRY (2015)
Spreading of pathology in neurodegenerative diseases: a focus on human studies
Johannes Brettschneider et al.
NATURE REVIEWS NEUROSCIENCE (2015)
Tau immunotherapy for Alzheimer's disease
Jan Torleif Pedersen et al.
TRENDS IN MOLECULAR MEDICINE (2015)
Neurodegeneration and microtubule dynamics: death by a thousand cuts
Jyoti Dubey et al.
FRONTIERS IN CELLULAR NEUROSCIENCE (2015)
Protein tyrosine phosphatases as potential therapeutic targets
Rong-jun He et al.
ACTA PHARMACOLOGICA SINICA (2014)
Alzheimer’s Disease and Environmental Exposure to Lead: The Epidemiologic Evidence and Potential Role of Epigenetics
Kelly M. Bakulski et al.
Current Alzheimer Research (2014)
Tau phosphorylation and tau mislocalization mediate soluble Aβ oligomer-induced AMPA glutamate receptor signaling deficits
Eric C. Miller et al.
EUROPEAN JOURNAL OF NEUROSCIENCE (2014)
Cdk5 activity in the brain - multiple paths of regulation
Kavita Shah et al.
JOURNAL OF CELL SCIENCE (2014)
Microtubules in neurons as information carriers
Erik W. Dent et al.
JOURNAL OF NEUROCHEMISTRY (2014)
Amyloid-β and Tau The Trigger and Bullet in Alzheimer Disease Pathogenesis
George S. Bloom
JAMA NEUROLOGY (2014)
βIII-Tubulin: biomarker of taxane resistance or drug target?
Roshan Karki et al.
EXPERT OPINION ON THERAPEUTIC TARGETS (2013)
Tau pathology and neurodegeneration
Maria Grazia Spillantini et al.
LANCET NEUROLOGY (2013)
Alzheimer disease therapy-moving from amyloid-β to tau
Ezio Giacobini et al.
NATURE REVIEWS NEUROLOGY (2013)
SYNAPTIC CHANGES IN ALZHEIMER'S DISEASE AND ITS MODELS
J. Pozueta et al.
NEUROSCIENCE (2013)
Proline: The Distribution, Frequency, Positioning, and Common Functional Roles of Proline and Polyproline Sequences in the Human Proteome
Alexander A. Morgan et al.
PLOS ONE (2013)
The case for soluble Aβ oligomers as a drug target in Alzheimer's disease
Franz Hefti et al.
TRENDS IN PHARMACOLOGICAL SCIENCES (2013)
Binding of the three-repeat domain of tau to phospholipid membranes induces an aggregated-like state of the protein
Georg Kuenze et al.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2012)
Structural and functional characterization of H2 haplotype MAPT promoter: Unique neurospecific domains and a hypoxia-inducible element would enhance rationally targeted tauopathy research for Alzheimer's disease
Bryan Maloney et al.
GENE (2012)
Evidence for Irreversible Inhibition of Glycogen Synthase Kinase-3β by Tideglusib
Juan Manuel Dominguez et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
Altered regulation of tau phosphorylation in a mouse model of down syndrome aging
Olivia Sheppard et al.
NEUROBIOLOGY OF AGING (2012)
Abnormal tau, mitochondrial dysfunction, impaired axonal transport of mitochondria, and synaptic deprivation in Alzheimer's disease
P. Hemachandra Reddy
BRAIN RESEARCH (2011)
Mitochondria as a Therapeutic Target for Aging and Neurodegenerative Diseases
P. H. Reddy et al.
Current Alzheimer Research (2011)
Cytoplasmic Linker Proteins Regulate Neuronal Polarization through Microtubule and Growth Cone Dynamics
Dorothee Neukirchen et al.
JOURNAL OF NEUROSCIENCE (2011)
Protein aggregate spreading in neurodegenerative diseases: Problems and perspectives
Seung-Jae Lee et al.
NEUROSCIENCE RESEARCH (2011)
Microtubules in Bacteria: Ancient Tubulins Build a Five-Protofilament Homolog of the Eukaryotic Cytoskeleton
Martin Pilhofer et al.
PLOS BIOLOGY (2011)
The K-ATP Channel Activator Diazoxide Ameliorates Amyloid-beta and Tau Pathologies and Improves Memory in the 3xTgAD Mouse Model of Alzheimer's Disease
Dong Liu et al.
JOURNAL OF ALZHEIMERS DISEASE (2010)
Phosphorylation of Tau at Thr212, Thr231, and Ser262 Combined Causes Neurodegeneration
Alejandra D. Alonso et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Quantitative Measurement of in Vivo Phosphorylation States of Cdk5 Activator p35 by Phos-tag SDS-PAGE
Tomohisa Hosokawa et al.
MOLECULAR & CELLULAR PROTEOMICS (2010)
Tau Mislocalization to Dendritic Spines Mediates Synaptic Dysfunction Independently of Neurodegeneration
Brian R. Hoover et al.
NEURON (2010)
Tau 6D and 6P Isoforms Inhibit Polymerization of Full-Length Tau in Vitro
Nichole E. LaPointe et al.
BIOCHEMISTRY (2009)
Glycogen synthase kinase 3: more than a namesake
Geetha Vani Rayasam et al.
BRITISH JOURNAL OF PHARMACOLOGY (2009)
Hyperphosphorylation and Aggregation of Tau in Laforin-deficient Mice, an Animal Model for Lafora Disease
Rajat Puri et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
The role of tau in neurodegeneration
Tania F. Gendron et al.
MOLECULAR NEURODEGENERATION (2009)
Advances in tau-focused drug discovery for Alzheimer's disease and related tauopathies
Kurt R. Brunden et al.
NATURE REVIEWS DRUG DISCOVERY (2009)
Microtubule assembly, organization and dynamics in axons and dendrites
Cecilia Conde et al.
NATURE REVIEWS NEUROSCIENCE (2009)
Intracellular amyloid-β in Alzheimer's disease
Frank M. LaFerla et al.
NATURE REVIEWS NEUROSCIENCE (2007)
Untangling the tau gene association with neurodegenerative disorders
Alan M. Pittman et al.
HUMAN MOLECULAR GENETICS (2006)
Structure of bacterial tubulin BtubA/B:: Evidence for horizontal gene transfer
D Schlieper et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Three- and four-repeat tau regulate the dynamic instability of two distinct microtubule subpopulations in qualitatively different manners - Implications for neurodegeneration
SF Levy et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Tau alteration and neuronal degeneration in tauopathies: mechanisms and models
R Brandt et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2005)
Unfolding the role of protein misfolding in neurodegenerative diseases
C Soto
NATURE REVIEWS NEUROSCIENCE (2003)
Presenilin, Notch, and the genesis and treatment of Alzheimer's disease
DJ Selkoe
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
Tau protein isoforms, phosphorylation and role in neurodegenerative disorders
L Buée et al.
BRAIN RESEARCH REVIEWS (2000)
分享论文
