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Article
Biochemistry & Molecular Biology
Increased LRRK2 kinase activity alters neuronal autophagy by disrupting the axonal transport of autophagosomes
C. Alexander Boecker et al.
Summary: Mutations in the LRRK2 gene associated with Parkinson's disease lead to defects in autophagosome transport, impairing effective degradation of autophagosomal cargo in neurons.
CURRENT BIOLOGY (2021)
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