期刊
EXPERIMENTAL CELL RESEARCH
卷 343, 期 1, 页码 73-81出版社
ELSEVIER INC
DOI: 10.1016/j.yexcr.2015.11.009
关键词
Extracellular matrix; Breast cancer; Splicing; Microstructure
资金
- DOD Breast Cancer Research Program [BC133875]
- L'Oreal USA for women in science program
- CDMRP [793705, BC133875] Funding Source: Federal RePORTER
The extracellular matrix in the healthy breast has an important tumor suppressive role, whereas the abnormal ECM in tumors can promote aggressiveness, and has been linked to breast cancer relapse, survival and resistance to chemotherapy. This review article gives an overview of the elements of the ECM which have been linked to prognosis of breast cancers, including changes in ECM protein composition, splicing, and microstructure. Published by Elsevier Inc.
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