期刊
ATLA-ALTERNATIVES TO LABORATORY ANIMALS
卷 49, 期 4, 页码 122-132出版社
SAGE PUBLICATIONS LTD
DOI: 10.1177/02611929211040824
关键词
alternatives; animal testing; chemical safety; new approach methodologies; next generation risk assessment; product safety; REACH; regulatory testing; safety science
资金
- Unilever
Despite advances in non-animal safety science, animal use for testing chemicals under REACH is increasing. Thought leaders in human health and environmental protection are urging the European Commission to embrace modern and innovative non-animal safety science to lead safe and sustainable innovation under the European Green Deal.
Animal use for testing chemicals under REACH continues to increase, despite advances in non-animal safety science during the past 15 years. The application of modern science and technology, and the use of 'next generation' weight-of-evidence assessment approaches, are embedded in EU guidance for establishing the safety of cosmetics and foods - and of the ingredients used in these products. However, this is still not the case for the regulation of chemicals. Under the new Chemicals Strategy for Sustainability, thought leaders in human health and environmental protection are calling on the European Commission to quickly embrace the benefits of modern and innovative non-animal safety science, in place of outdated animal testing, if the EU is to be a leader in safe and sustainable innovation under the European Green Deal transformational change ambitions. The European Commission also needs to enable companies to meet their legal obligation to only conduct animal testing as a last resort, by providing a more flexible, science-based and consistent regulatory framework for assuring chemical safety, which supports the integration of data from different sources. We are at a tipping point for closing the gap between regulatory chemicals testing and modern safety science. It is time to join forces, across policy makers, scientists, regulators and lawyers, to lead the paradigm shift needed to deliver what EU citizens want - namely, chemicals and products that are safe and sustainable, without resorting to animal testing.
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