Editorial Commentary: Leukocyte-Poor Platelet-Rich Plasma Decreases Retear Rate in Arthroscopic Rotator Cuff Repair: Platelet-Rich Plasma Type Matters

Numerous studies, including several meta-analysis reviews of platelet-rich plasma (PRP) in the setting of arthroscopic rotator cuff repair, show mixed results. Focusing on specific types of PRP configuration may elucidate which provide value and which do not. Recent meta-analysis demonstrates that leukocyte-poor PRP or pure PRP treatment is shown to decrease retear rate and patient-reported outcome measures after arthroscopic rotator cuff repair of the shoulder. Meta-analyses resulting in conflicting results may be attributed to different study inclusion and exclusion criteria and date of search.

Automated summary

Multiple studies on platelet-rich plasma (PRP) in arthroscopic rotator cuff repair show mixed results, with recent meta-analysis highlighting the benefits of leukocyte-poor or pure PRP in reducing retear rate. Conflicting results in meta-analyses may stem from variations in study inclusion and exclusion criteria as well as search dates.