4.7 Review

The Reactive Species Interactome in the Brain

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Biochemistry & Molecular Biology

Senescence in Post-Mitotic Cells: A Driver of Aging?

Thomas von Zglinicki et al.

Summary: Cell senescence is not limited to proliferating cells, but can also occur in non-dividing cells. Different senescence domains interact with each other and may play a significant role in mammalian aging.

ANTIOXIDANTS & REDOX SIGNALING (2021)

Review Physiology

Endogenous flux of nitric oxide: Citrulline is preferred to Arginine

Zahra Bahadoran et al.

Summary: Citrulline is more favorable for nitric oxide production compared to arginine due to its higher absorption and reabsorption rates, and cells prefer to use citrulline instead of arginine to increase NO output.

ACTA PHYSIOLOGICA (2021)

Article Biochemistry & Molecular Biology

Loss of ferroportin induces memory impairment by promoting ferroptosis in Alzheimer's disease

Wen-Dai Bao et al.

Summary: Iron homeostasis disturbance and ferroptosis play critical roles in the pathogenesis and progression of Alzheimer's disease, and targeting these processes may provide promising therapeutic approaches for this disease.

CELL DEATH AND DIFFERENTIATION (2021)

Article Psychiatry

Association of Peroxiredoxin 1 and brain-derived neurotrophic factor serum levels with depression and anxiety symptoms in patients with irritable bowel syndrome

Yu Zhang et al.

Summary: This study found a significant association between elevated serum PRDX1 and decreased BDNF levels with anxiety and depression symptoms in IBS patients. These results suggest that PRDX1 may be an important target for IBS treatment in addressing both intestinal and psychological symptoms.

GENERAL HOSPITAL PSYCHIATRY (2021)

Article Biochemistry & Molecular Biology

The role of glutamate oxaloacetate transaminases in sulfite biosynthesis and H2S metabolism

Anna-Theresa Mellis et al.

Summary: Molybdenum cofactor deficiency and isolated sulfite oxidase deficiency are rare genetic disorders caused by impairment of the mitochondrial enzyme sulfite oxidase. Investigation of the contributions of cytosolic and mitochondrial glutamate oxaloacetate transaminase (GOT) in cellular extracts revealed that the cytosolic isoform GOT1 is primarily responsible for sulfite production. Loss of sulfite oxidase activity leads to accumulation of sulfite, H2S, and persulfidated cysteine and glutathione, suggesting an increase in SQR protein levels. Surprisingly, under conditions of sulfite toxicity, none of the known H2S-producing pathways were found to be upregulated, indicating an alternative route of sulfite-induced shift from oxidative to H2S dependent cysteine catabolism.

REDOX BIOLOGY (2021)

Review Biochemistry & Molecular Biology

Interplay among Oxidative Stress, Methylglyoxal Pathway and S-Glutathionylation

Lidia de Bari et al.

Summary: The balance between ROS and MGO metabolism is crucial for maintaining redox homeostasis and biological functions in cells, preventing oxidative damage. Changes in GSH and MGO levels under different conditions can impact cell responses and signaling pathways.

ANTIOXIDANTS (2021)

Review Medicine, Research & Experimental

Roles of nitric oxide and polyamines in brain tumor growth

Monika Szeliga et al.

Summary: Nitric oxide and polyamines play key roles in brain tumors, contributing to their differentiation, growth, and resistance to therapy. Increased activities of NO- and polyamine-synthesizing enzymes are often correlated with higher malignancy in brain tumors.

ADVANCES IN MEDICAL SCIENCES (2021)

Review Food Science & Technology

Glutathione peroxidase-1 and neuromodulation: Novel potentials of an old enzyme

Garima Sharma et al.

Summary: Glutathione peroxidase (GPx) acts in coordination with other signaling molecules to exert its antioxidant role and may serve as a neuro-modulator in certain neuropsychiatric conditions. This review aims to highlight the mechanistic scenarios mediated by the GPx/GPx-1 gene in impacting neurodegenerative and neuropsychiatric disorders, providing new insights for therapeutic interventions.

FOOD AND CHEMICAL TOXICOLOGY (2021)

Article Biochemistry & Molecular Biology

Lipid peroxidation derived reactive carbonyl species in free and conjugated forms as an index of lipid peroxidation: limits and perspectives

Alessandra Altomare et al.

Summary: The interest in protein carbonylation has grown because protein adducts are recognized as being involved in the damaging action of oxidative stress. With the latest analytical methods, a deeper understanding of the molecular mechanisms of oxidative stress can be gained.

REDOX BIOLOGY (2021)

Article Neurosciences

The clinical significance of glutathione peroxidase 2 in glioblastoma multiforme

Bangming Guo et al.

Summary: The study demonstrated that GPX2 could serve as a potential diagnostic and prognostic indicator for GBM, with patients having higher GPX2 levels showing poorer prognosis. The chemokine-signaling pathway may play a role in GPX2 function.

TRANSLATIONAL NEUROSCIENCE (2021)

Review Neurosciences

Hydrogen sulfide intoxication induced brain injury and methylene blue

Philippe Haouzi et al.

NEUROBIOLOGY OF DISEASE (2020)

Article Biochemistry & Molecular Biology

2-Hydroxyglutarate in Cancer Cells

Petr Jezek

ANTIOXIDANTS & REDOX SIGNALING (2020)

Review Chemistry, Medicinal

Potential implications of hydrogen peroxide in the pathogenesis and therapeutic strategies of gliomas

Ying Zhou et al.

ARCHIVES OF PHARMACAL RESEARCH (2020)

Review Behavioral Sciences

Adult neurogenesis, human after all (again): Classic, optimized, and future approaches

Paul J. Lucassen et al.

BEHAVIOURAL BRAIN RESEARCH (2020)

Review Chemistry, Medicinal

Targeting iNOS As a Valuable Strategy for the Therapy of Glioma

Cristina Maccallini et al.

CHEMMEDCHEM (2020)

Review Neurosciences

Oxidative Stress in the Pathogenesis of Alzheimer's Disease and Cerebrovascular Disease with Therapeutic Implications

Anamaria Jurcau et al.

CNS & NEUROLOGICAL DISORDERS-DRUG TARGETS (2020)

Review Gastroenterology & Hepatology

Targeting hallmarks of cancer to enhance radiosensitivity in gastrointestinal cancers

Amy M. Buckley et al.

NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY (2020)

Editorial Material Multidisciplinary Sciences

Translating preclinical models to humans

Douglas K. Brubaker et al.

SCIENCE (2020)

Review Neurosciences

Cellular Senescence in Neurodegenerative Diseases

Carmen Martinez-Cue et al.

FRONTIERS IN CELLULAR NEUROSCIENCE (2020)

Article Multidisciplinary Sciences

Epileptic brain fluorescent imaging reveals apigenin can relieve the myeloperoxidase-mediated oxidative stress and inhibit ferroptosis

Chenwen Shao et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2020)

Review Neurosciences

Neurodegenerative Diseases - Is Metabolic Deficiency the Root Cause?

Vignayanandam Ravindernath Muddapu et al.

FRONTIERS IN NEUROSCIENCE (2020)

Review Neurosciences

Mitochondria dysfunction in the pathogenesis of Alzheimer's disease: recent advances

Wenzhang Wang et al.

MOLECULAR NEURODEGENERATION (2020)

Review Cell Biology

Reactive oxygen species (ROS) as pleiotropic physiological signalling agents

Helmut Sies et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2020)

Article Biochemistry & Molecular Biology

Prdx6 Plays a Main Role in the Crosstalk between Aging and Metabolic Sarcopenia

Francesca Pacifici et al.

ANTIOXIDANTS (2020)

Article Engineering, Biomedical

Nanosized zeolites as a gas delivery platform in a glioblastoma model

Clement Anfray et al.

BIOMATERIALS (2020)

Review Cell Biology

The Complex Interplay between Antioxidants and ROS in Cancer

Isaac S. Harris et al.

TRENDS IN CELL BIOLOGY (2020)

Review Biochemistry & Molecular Biology

Oxidative Stress and Redox-Modulating Therapeutics in Inflammatory Bowel Disease

Arno R. Bourgonje et al.

TRENDS IN MOLECULAR MEDICINE (2020)

Article Biochemistry & Molecular Biology

Findings in redox biology: From H2O2to oxidative stress

Helmut Sies

JOURNAL OF BIOLOGICAL CHEMISTRY (2020)

Article Neurosciences

Peroxiredoxin 6 mediates protective function of astrocytes in Aβ proteostasis

Joanna E. Pankiewicz et al.

MOLECULAR NEURODEGENERATION (2020)

Review Biochemistry & Molecular Biology

The Advanced Lipoxidation End-Product Malondialdehyde-Lysine in Aging and Longevity

Mariona Jove et al.

ANTIOXIDANTS (2020)

Review Biochemistry & Molecular Biology

Peroxiredoxins in Neurodegenerative Diseases

Monika Szeliga

ANTIOXIDANTS (2020)

Article Cell Biology

Mitochondrial ROS prime the hyperglycemic shift from apoptosis to necroptosis

Matthew A. Deragon et al.

CELL DEATH DISCOVERY (2020)

Article Neurosciences

The relationship between oxidative stress and acute ischemic stroke severity and functional outcome

Wael M. Elsayed et al.

EGYPTIAN JOURNAL OF NEUROLOGY PSYCHIATRY AND NEUROSURGERY (2020)

Review Biochemistry & Molecular Biology

Redox Mechanisms in Neurodegeneration: From Disease Outcomes to Therapeutic Opportunities

Juan I. Sbodio et al.

ANTIOXIDANTS & REDOX SIGNALING (2019)

Review Biochemistry & Molecular Biology

Molecular Mechanisms of Nitric Oxide in Cancer Progression, Signal Transduction, and Metabolism

Veena Somasundaram et al.

ANTIOXIDANTS & REDOX SIGNALING (2019)

Article Pharmacology & Pharmacy

Sulfite protects neurons from oxidative stress

Yuka Kimura et al.

BRITISH JOURNAL OF PHARMACOLOGY (2019)

Review Neurosciences

The Delicate Equilibrium between Oxidants and Antioxidants in Brain Glioma

Maria Jesus Ramirez-Exposito et al.

CURRENT NEUROPHARMACOLOGY (2019)

Article Neurosciences

PRDX6 Inhibits Neurogenesis through Downregulation of WDFY1-Mediated TLR4 Signal

In Jun Yeo et al.

MOLECULAR NEUROBIOLOGY (2019)

Review Neurosciences

Mitochondrial dysfunction in neurodegenerative diseases and the potential countermeasure

Yan Wang et al.

CNS NEUROSCIENCE & THERAPEUTICS (2019)

Article Developmental Biology

Ferroptosis and Brain Injury

Leslie Magtanong et al.

DEVELOPMENTAL NEUROSCIENCE (2019)

Review Biochemistry & Molecular Biology

Hydrogen sulfide, reactive sulfur species and coping with reactive oxygen species

Kenneth R. Olson

FREE RADICAL BIOLOGY AND MEDICINE (2019)

Article Chemistry, Inorganic & Nuclear

Saying NO to H2S: A Story of HNO, HSNO, and SSNO-

Ivana Ivanovic-Burmazovic et al.

INORGANIC CHEMISTRY (2019)

Article Oncology

Targeting IDH1-Mutated Malignancies with NRF2 Blockade

Yang Liu et al.

JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2019)

Editorial Material Clinical Neurology

The global burden of neurological disorders

William M. Carroll

LANCET NEUROLOGY (2019)

Review Neurosciences

Nitric Oxide, Iron and Neurodegeneration

Chao Liu et al.

FRONTIERS IN NEUROSCIENCE (2019)

Article Geriatrics & Gerontology

Dentate Gyrus Peroxiredoxin 6 Levels Discriminate Aged Unimpaired From Impaired Rats in a Spatial Memory Task

Jana Lubec et al.

FRONTIERS IN AGING NEUROSCIENCE (2019)

Review Clinical Neurology

H2S-based therapies for ischaemic stroke: opportunities and challenges

Jia Jia et al.

STROKE AND VASCULAR NEUROLOGY (2019)

Review Oncology

Friend or foe-IDH1 mutations in glioma 10 years on

L. Eric Huang

CARCINOGENESIS (2019)

Review Cell Biology

ROS Generation and Antioxidant Defense Systems in Normal and Malignant Cells

Anastasiya Snezhkina et al.

OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2019)

Article Cardiac & Cardiovascular Systems

Tissue-Specific Metabolic Profiles After Prolonged Cardiac Arrest Reveal Brain Metabolome Dysfunction Predominantly After Resuscitation

Jaewoo Choi et al.

JOURNAL OF THE AMERICAN HEART ASSOCIATION (2019)

Review Pharmacology & Pharmacy

Mitochondria as Potential Targets in Alzheimer Disease Therapy: An Update

Giovanna Cenini et al.

FRONTIERS IN PHARMACOLOGY (2019)

Review Biochemistry & Molecular Biology

Programmed Cell-Death by Ferroptosis: Antioxidants as Mitigators

Naroa Kajarabille et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2019)

Review Physiology

Cellular Metabolism in Lung Health and Disease

Gang Liu et al.

ANNUAL REVIEW OF PHYSIOLOGY, VOL 81 (2019)

Article Medicine, General & Internal

Ischaemic stroke

Bruce C. Campbell et al.

NATURE REVIEWS DISEASE PRIMERS (2019)

Review Biochemistry & Molecular Biology

Functions and dysfunctions of nitric oxide in brain

Pol Picon-Pages et al.

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2019)

Editorial Material Medicine, General & Internal

Reducing the global burden of depression: a Lancet-World Psychiatric Association Commission

Helen Herrman et al.

LANCET (2019)

Review Cell Biology

The dynamic nature of senescence in cancer

Soyoung Lee et al.

NATURE CELL BIOLOGY (2019)

Article Multidisciplinary Sciences

The Tri-phasic Role of Hydrogen Peroxide in Blood-Brain Barrier Endothelial cells

Chinchusha Anasooya Shaji et al.

SCIENTIFIC REPORTS (2019)

Article Biochemistry & Molecular Biology

HIF-1α protects against oxidative stress by directly targeting mitochondria

Hong-Sheng Li et al.

REDOX BIOLOGY (2019)

Article Medicine, General & Internal

Brain metastases

Achal Singh Achrol et al.

NATURE REVIEWS DISEASE PRIMERS (2019)

Review Medicine, General & Internal

Hypoxia Imaging and Adaptive Radiotherapy: A State-of-the-Art Approach in the Management of Glioma

Michael Gerard et al.

FRONTIERS IN MEDICINE (2019)

Review Biochemistry & Molecular Biology

The interrelationship between cerebral ischemic stroke and glioma: a comprehensive study of recent reports

Mrinal K. Ghosh et al.

SIGNAL TRANSDUCTION AND TARGETED THERAPY (2019)

Review Cell Biology

Hypoxia-Modified Cancer Cell Metabolism

Wafaa Al Tameemi et al.

FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (2019)

Review Biochemistry & Molecular Biology

The role of mitochondrial ROS in the aging brain

Rhoda Stefanatos et al.

FEBS LETTERS (2018)

Review Biochemistry & Molecular Biology

Redox Signaling, Neuroinflammation, and Neurodegeneration

Gabriela Aguilera et al.

ANTIOXIDANTS & REDOX SIGNALING (2018)

Review Pharmacology & Pharmacy

H2S and polysulfide metabolism: Conventional and unconventional pathways

Kenneth R. Olson

BIOCHEMICAL PHARMACOLOGY (2018)

Review Biochemistry & Molecular Biology

Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018

Lorenzo Galluzzi et al.

CELL DEATH AND DIFFERENTIATION (2018)

Review Medicine, Research & Experimental

Cellular senescence in brain aging and neurodegenerative diseases: evidence and perspectives

Darren J. Baker et al.

JOURNAL OF CLINICAL INVESTIGATION (2018)

Review Cardiac & Cardiovascular Systems

Nitric oxide signalling in cardiovascular health and disease

Charlotte Farah et al.

NATURE REVIEWS CARDIOLOGY (2018)

Review Neurosciences

The Axon-Myelin Unit in Development and Degenerative Disease

Ruth M. Stassart et al.

FRONTIERS IN NEUROSCIENCE (2018)

Review Biochemistry & Molecular Biology

13 reasons why the brain is susceptible to oxidative stress

James Nathan Cobley et al.

REDOX BIOLOGY (2018)

Article Biochemistry & Molecular Biology

Metabolism of hydrogen sulfide (H2S) and Production of Reactive Sulfur Species (RSS) by superoxide dismutase

Kenneth R. Olson et al.

REDOX BIOLOGY (2018)

Review Biochemistry & Molecular Biology

Neuroprotection through flavonoid: Enhancement of the glyoxalase pathway

Joel R. Frandsen et al.

REDOX BIOLOGY (2018)

Review Neurosciences

Hydrogen sulfide, nitric oxide, and neurodegenerative disorders

Sandesh Panthi et al.

TRANSLATIONAL NEURODEGENERATION (2018)

Review Biochemistry & Molecular Biology

Typical and Atypical Inducers of Lysosomal Cell Death: A Promising Anticancer Strategy

Antoni Domagala et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2018)

Review Medicine, General & Internal

Primary brain tumours in adults

Sarah Lapointe et al.

LANCET (2018)

Review Neurosciences

The role of brain vasculature in neurodegenerative disorders

Melanie D. Sweeney et al.

NATURE NEUROSCIENCE (2018)

Review Neurosciences

Converging pathways in neurodegeneration, from genetics to mechanisms

Li Ga et al.

NATURE NEUROSCIENCE (2018)

Review Neurosciences

Bidirectional Microglia-Neuron Communication in Health and Disease

Zsuzsanna Szepesi et al.

FRONTIERS IN CELLULAR NEUROSCIENCE (2018)

Editorial Material Cell Biology

Mechanism and disease implications of necroptosis and neuronal inflammation

Sara R. Oliveira et al.

CELL DEATH & DISEASE (2018)

Article Medicine, Research & Experimental

A carnosine analog mitigates metabolic disorders of obesity by reducing carbonyl stress

Ethan J. Anderson et al.

JOURNAL OF CLINICAL INVESTIGATION (2018)

Review Neurosciences

Neuronal nitric oxide synthase and affective disorders

Qi-Gang Zhou et al.

IBRO REPORTS (2018)

Review Peripheral Vascular Disease

Stroke in the 21st Century: A Snapshot of the Burden, Epidemiology, and Quality of Life

Eric S. Donkor

STROKE RESEARCH AND TREATMENT (2018)

Article Biochemistry & Molecular Biology

Glutathione peroxidase 4: a new player in neurodegeneration?

B. R. Cardoso et al.

MOLECULAR PSYCHIATRY (2017)

Review Biochemistry & Molecular Biology

Role of 4-hydroxy-2-nonenal (HNE) in the pathogenesis of alzheimer disease and other selected age-related neurodegenerative disorders

Fabio Di Domenico et al.

FREE RADICAL BIOLOGY AND MEDICINE (2017)

Article Biochemistry & Molecular Biology

Mechanisms of myeloperoxidase catalyzed oxidation of H2S by H2O2 or O2 to produce potent protein Cys-polysulfide-inducing species

Dorottya Garai et al.

FREE RADICAL BIOLOGY AND MEDICINE (2017)

Article Biochemistry & Molecular Biology

Targeting antioxidant enzyme expression as a therapeutic strategy for ischemic stroke

Stephanie M. Davis et al.

NEUROCHEMISTRY INTERNATIONAL (2017)

Review Clinical Neurology

Biomarkers for depression: recent insights, current challenges and future prospects

Rebecca Strawbridge et al.

NEUROPSYCHIATRIC DISEASE AND TREATMENT (2017)

Review Biochemistry & Molecular Biology

Oxidative Stress

Helmut Sies et al.

ANNUAL REVIEW OF BIOCHEMISTRY, VOL 86 (2017)

Review Biochemistry & Molecular Biology

Ferroptosis: A Regulated Cell Death Nexus Linking Metabolism, Redox Biology, and Disease

Brent R. Stockwell et al.

Review Biochemistry & Molecular Biology

Beyond a Gasotransmitter: Hydrogen Sulfide and Polysulfide in Cardiovascular Health and Immune Response

Shuai Yuan et al.

ANTIOXIDANTS & REDOX SIGNALING (2017)

Review Medicine, Research & Experimental

Hydrogen sulfide therapy in brain diseases: from bench to bedside

Ju-yi Zhang et al.

MEDICAL GAS RESEARCH (2017)

Review Medicine, Research & Experimental

The role of nitric oxide in stroke

Zhou-qing Chen et al.

MEDICAL GAS RESEARCH (2017)

Review Neurosciences

Cellular mechanisms of peroxynitrite-induced neuronal death

Kristina Ramdial et al.

BRAIN RESEARCH BULLETIN (2017)

Review Biochemistry & Molecular Biology

NOS Expression and NO Function in Glioma and Implications for Patient Therapies

Anh N. Tran et al.

ANTIOXIDANTS & REDOX SIGNALING (2017)

Review Biochemistry & Molecular Biology

Clinically Evaluated Cancer Drugs Inhibiting Redox Signaling

D. Lynn Kirkpatrick et al.

ANTIOXIDANTS & REDOX SIGNALING (2017)

Article Biochemistry & Molecular Biology

Lipid peroxidation in cell death

Michael M. Gaschler et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2017)

Article Neurosciences

Oxidative Stress in Neurodegenerative Diseases

Ewa Niedzielska et al.

MOLECULAR NEUROBIOLOGY (2016)

Article Medicine, Research & Experimental

Methylglyoxal (MGO) inhibits proliferation and induces cell death of human glioblastoma multiforme T98G and U87MG cells

Monika Paul-Samojedny et al.

BIOMEDICINE & PHARMACOTHERAPY (2016)

Review Biochemistry & Molecular Biology

Alpha-Ketoglutarate: Physiological Functions and Applications

Nan Wu et al.

BIOMOLECULES & THERAPEUTICS (2016)

Review Chemistry, Multidisciplinary

Superoxide Ion: Generation and Chemical Implications

Maan Hayyan et al.

CHEMICAL REVIEWS (2016)

Review Behavioral Sciences

Myeloperoxidase: Bridging the gap in neurodegeneration

R. S. Ray et al.

NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS (2016)

Review Pharmacology & Pharmacy

Roles of peroxiredoxins in cancer, neurodegenerative diseases and inflammatory diseases

Mi Hee Park et al.

PHARMACOLOGY & THERAPEUTICS (2016)

Review Cell Biology

ROS homeostasis and metabolism: a dangerous liason in cancer cells

E. Panieri et al.

CELL DEATH & DISEASE (2016)

Review Oncology

Hypoxia and metabolic adaptation of cancer cells

K. L. Eales et al.

ONCOGENESIS (2016)

Review Medicine, Research & Experimental

The role of hydrogen sulfide in stroke

Yang Dou et al.

MEDICAL GAS RESEARCH (2016)

Review Biochemistry & Molecular Biology

On the role of 4-hydroxynonenal in health and disease

Miklos Csala et al.

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2015)

Article Endocrinology & Metabolism

Vascular AGE-ing by methylglyoxal: the past, the present and the future

Casper G. Schalkwijk

DIABETOLOGIA (2015)

Article Biochemistry & Molecular Biology

Mechanistic characterization of the thioredoxin system in the removal of hydrogen peroxide

Venkat R. Pannala et al.

FREE RADICAL BIOLOGY AND MEDICINE (2015)

Review Cell Biology

Markers of Oxidative Stress and Neuroprogression in Depression Disorder

Magdalena Vavakova et al.

OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2015)

Article Cell Biology

Antioxidants can increase melanoma metastasis in mice

Kristell Le Gal et al.

SCIENCE TRANSLATIONAL MEDICINE (2015)

Editorial Material Cell Biology

Cracking the code of neuronal apoptosis and survival

S. Cavallaro

CELL DEATH & DISEASE (2015)

Review Biochemistry & Molecular Biology

Oxidative stress: a concept in redox biology and medicine

Helmut Sies

REDOX BIOLOGY (2015)

Article Biochemistry & Molecular Biology

Reperfusion injury and reactive oxygen species: The evolution of a concept

D. Neil Granger et al.

REDOX BIOLOGY (2015)

Article Pharmacology & Pharmacy

Interactions of hydrogen sulfide with myeloperoxidase

Zoltan Palinkas et al.

BRITISH JOURNAL OF PHARMACOLOGY (2015)

Article Multidisciplinary Sciences

A Meta-Analysis of Oxidative Stress Markers in Depression

Tao Liu et al.

PLOS ONE (2015)

Biographical-Item Biochemistry & Molecular Biology

Redox Pioneer: Professor Helmut Sies

Dean P. Jones et al.

ANTIOXIDANTS & REDOX SIGNALING (2014)

Review Biochemistry & Molecular Biology

Production and Physiological Effects of Hydrogen Sulfide

Hideo Kimura

ANTIOXIDANTS & REDOX SIGNALING (2014)

Review Biochemistry & Molecular Biology

Pathophysiology of circulating xanthine oxidoreductase: New emerging roles for a multi-tasking enzyme

Maria Giulia Battelli et al.

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2014)

Article Neurosciences

Oxidative Stress and Psychological Disorders

Samina Salim

CURRENT NEUROPHARMACOLOGY (2014)

Article Cell Biology

Antioxidants Accelerate Lung Cancer Progression in Mice

Volkan I. Sayin et al.

SCIENCE TRANSLATIONAL MEDICINE (2014)

Review Multidisciplinary Sciences

Reactive Carbonyl Species In Vivo: Generation and Dual Biological Effects

Halyna M. Semchyshyn

SCIENTIFIC WORLD JOURNAL (2014)

Review Biochemistry & Molecular Biology

Oxidative Stress and the Use of Antioxidants in Stroke

Rachel Shirley et al.

ANTIOXIDANTS (2014)

Review Chemistry, Multidisciplinary

Targeting reactive nitrogen species: a promising therapeutic strategy for cerebral ischemia-reperfusion injury

Xing-miao Chen et al.

ACTA PHARMACOLOGICA SINICA (2013)

Review Biochemistry & Molecular Biology

Lipid peroxidation triggers neurodegeneration: A redox proteomics view into the Alzheimer disease brain

Rukhsana Sultana et al.

FREE RADICAL BIOLOGY AND MEDICINE (2013)

Review Biochemistry & Molecular Biology

Hydrogen Sulfide, the Next Potent Preventive and Therapeutic Agent in Aging and Age-Associated Diseases

Yuan Zhang et al.

MOLECULAR AND CELLULAR BIOLOGY (2013)

Review Biochemistry & Molecular Biology

Hydrogen sulfide chemical biology: Pathophysiological roles and detection

Gopi K. Kolluru et al.

NITRIC OXIDE-BIOLOGY AND CHEMISTRY (2013)

Review Cell Biology

ROS and Brain Diseases: The Good, the Bad, and the Ugly

Aurel Popa-Wagner et al.

OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2013)

Article Geriatrics & Gerontology

Carbonyl Stress in Aging Process: Role of Vitamins and Phytochemicals as Redox Regulators

Volkan Ergin et al.

Aging and Disease (2013)

Article Biochemistry & Molecular Biology

Lipid peroxidation dysregulation in ischemic stroke: Plasma 4-HNE as a potential biomarker?

Wan-Chi Lee et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2012)

Review Biochemistry & Molecular Biology

Cellular stress responses, hormetic phytochemicals and vitagenes in aging and longevity

Vittorio Calabrese et al.

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2012)

Article Biochemistry & Molecular Biology

Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death

Scott J. Dixon et al.

Review Cardiac & Cardiovascular Systems

Nitric oxide synthases: regulation and function

Ulrich Foerstermann et al.

EUROPEAN HEART JOURNAL (2012)

Article Biochemistry & Molecular Biology

Gpx4 ablation in adult mice results in a lethal phenotype accompanied by neuronal loss in brain

Si-Eun Yoo et al.

FREE RADICAL BIOLOGY AND MEDICINE (2012)

Review Biochemistry & Molecular Biology

Peroxiredoxin Functions as a Peroxidase and a Regulator and Sensor of Local Peroxides

Sue Goo Rhee et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2012)

Review Endocrinology & Metabolism

Nitric oxide: considerations for the treatment of ischemic stroke

Nicole A. Terpolilli et al.

JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM (2012)

Review Biochemistry & Molecular Biology

Physiological Roles of Mitochondrial Reactive Oxygen Species

Laura A. Sena et al.

MOLECULAR CELL (2012)

Editorial Material Biochemistry & Molecular Biology

Peroxiredoxin sets the brain on fire after stroke

Lidia Garcia-Bonilla et al.

NATURE MEDICINE (2012)

Review Cell Biology

Mechanism of Oxidative Stress in Neurodegeneration

Sonia Gandhi et al.

OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2012)

Article Multidisciplinary Sciences

Adult Neurogenesis Transiently Generates Oxidative Stress

Noah M. Walton et al.

PLOS ONE (2012)

Review Cell Biology

Oxidative stress and adult neurogenesis-Effects of radiation and superoxide dismutase deficiency

Ting-Ting Huang et al.

SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY (2012)

Review Pharmacology & Pharmacy

Nitric oxide synthase uncoupling: A therapeutic target in cardiovascular diseases

Nathan D. Roe et al.

VASCULAR PHARMACOLOGY (2012)

Article Information Science & Library Science

Omega-3s: Fishing for a Mechanism

Ethan J. Anderson et al.

SCIENTIST (2012)

Article Pathology

Dual Functionality of Myeloperoxidase in Rotenone-Exposed Brain-Resident Immune Cells

Chi Young Chang et al.

AMERICAN JOURNAL OF PATHOLOGY (2011)

Review Biochemistry & Molecular Biology

Significance of Brain Tissue Oxygenation and the Arachidonic Acid Cascade in Stroke

Cameron Rink et al.

ANTIOXIDANTS & REDOX SIGNALING (2011)

Review Biochemistry & Molecular Biology

Superoxide Dismutases: Role in Redox Signaling, Vascular Function, and Diseases

Tohru Fukai et al.

ANTIOXIDANTS & REDOX SIGNALING (2011)

Review Biochemistry & Molecular Biology

Hallmarks of Cancer: The Next Generation

Douglas Hanahan et al.

Review Neurosciences

Pathophysiology, treatment, and animal and cellular models of human ischemic stroke

Trent M. Woodruff et al.

MOLECULAR NEURODEGENERATION (2011)

Article Biochemistry & Molecular Biology

Delineating the Role of Glutathione Peroxidase 4 in Protecting Cells Against Lipid Hydroperoxide Damage and in Alzheimer's Disease

Min-Hyuk Yoo et al.

ANTIOXIDANTS & REDOX SIGNALING (2010)

Article Chemistry, Medicinal

Reaction of Hydrogen Sulfide with the Neutrophil Oxidant Hypochlorous Acid to Generate Polysulfides

Peter Nagy et al.

CHEMICAL RESEARCH IN TOXICOLOGY (2010)

Review Nutrition & Dietetics

Superoxide Anion, Uncoupling Proteins and Alzheimer's Disease

Zhaofei Wu et al.

JOURNAL OF CLINICAL BIOCHEMISTRY AND NUTRITION (2010)

Article Neurosciences

Hydrogen Sulfide Scavenges the Cytotoxic Lipid Oxidation Product 4-HNE

Sabine M. Schreier et al.

NEUROTOXICITY RESEARCH (2010)

Article Psychiatry

Increased xanthine oxidase in the thalamus and putamen in depression

Tanja Maria Michel et al.

WORLD JOURNAL OF BIOLOGICAL PSYCHIATRY (2010)

Article Clinical Neurology

Glutathione Peroxidase Activity Modulates Recovery in the Injured Immature Brain

Kyoko Tsuru-Aoyagi et al.

ANNALS OF NEUROLOGY (2009)

Article Biochemistry & Molecular Biology

Proteomic identification of carbonylated proteins in the monkey hippocampus after ischemia-reperfusion

Shinji Oikawa et al.

FREE RADICAL BIOLOGY AND MEDICINE (2009)

Article Neurosciences

Glutathione Peroxidase Overexpression Does Not Rescue Impaired Neurogenesis in the Injured Immature Brain

Matthew B. Potts et al.

JOURNAL OF NEUROSCIENCE RESEARCH (2009)

Article Medicine, Research & Experimental

Oxidative stress and erythrocyte acetylcholinesterase (AChE) in hypertensive and ischemic patients of both acute and chronic stages

Maisa de Carvalho Correa et al.

BIOMEDICINE & PHARMACOTHERAPY (2008)

Article Biochemistry & Molecular Biology

Methylglyoxal causes strong weakening of detoxifying capacity and apoptotic cell death in rat hippocampal neurons

Silvia Di Loreto et al.

INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2008)

Review Biochemistry & Molecular Biology

Oxidative stress and covalent modification of protein with bioactive aldehydes

Paul A. Grimsrud et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2008)

Article Geriatrics & Gerontology

Glutathione peroxidase enzyme activity in aging

Sara E. Espinoza et al.

JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES (2008)

Article Neurosciences

Neuronal nitric oxide synthase plays a key role in CNS demyelination

David Linares et al.

JOURNAL OF NEUROSCIENCE (2006)

Article Medicine, General & Internal

Projections of global mortality and burden of disease from 2002 to 2030

Colin D. Mathers et al.

PLOS MEDICINE (2006)

Article Clinical Neurology

Time is brain - Quantified

JL Saver

STROKE (2006)

Article Cardiac & Cardiovascular Systems

Mitochondria-derived reactive oxygen species dilate cerebral arteries by activating Ca2+ sparks

Q Xi et al.

CIRCULATION RESEARCH (2005)

Review Clinical Neurology

Nitric oxide and adult neurogenesis in health and disease

C Estrada et al.

NEUROSCIENTIST (2005)

Article Biochemistry & Molecular Biology

Aging effect on myeloperoxidase in rat kidney and its modulation by calorie restriction

TG Son et al.

FREE RADICAL RESEARCH (2005)

Article Developmental Biology

Overexpression of glutathione peroxidase protects immature murine neurons from oxidative stress

CW McLean et al.

DEVELOPMENTAL NEUROSCIENCE (2005)

Review Biochemistry & Molecular Biology

Oxidative stress in neurodegeneration: cause or consequence?

JK Andersen

NATURE MEDICINE (2004)

Article Multidisciplinary Sciences

Myeloperoxidase up-regulates the catalytic activity of inducible nitric oxide synthase by preventing nitric oxide feedback inhibition

S Galijasevic et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)

Article Multidisciplinary Sciences

Nitric oxide negatively regulates mammalian adult neurogenesis

MA Packer et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)

Article Immunology

Inflammatory response and glutathione peroxidase in a model of stroke

N Ishibashi et al.

JOURNAL OF IMMUNOLOGY (2002)

Article Biochemistry & Molecular Biology

Mechanisms of action of malondialdehyde and 4-hydroxynonenal on xanthine oxidoreductase

G Cighetti et al.

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2001)

Article Biochemistry & Molecular Biology

Catalase catalyzes nitrotyrosine formation from sodium azide and hydrogen peroxide

K Ogino et al.

FREE RADICAL RESEARCH (2001)

Article Biochemistry & Molecular Biology

Mechanism of reaction of myeloperoxidase with nitrite

U Burner et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2000)

Article Biochemistry & Molecular Biology

Cu,Zn-superoxide dismutase-dependent apoptosis induced by nitric oxide in neuronal cells

MR Ciriolo et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2000)