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Antoine Chaillon et al.
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Ryan C. Burdick et al.
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Adarsh Dharan et al.
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Tomofumi Nakamura et al.
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Human Immunodeficiency Virus Drug Resistance: 2018 Recommendations of the International Antiviral Society-USA Panel
Huldrych F. Gunthard et al.
CLINICAL INFECTIOUS DISEASES (2019)
Novel Central Nervous System (CNS)-Targeting Protease Inhibitors for Drug-Resistant HIV Infection and HIV-Associated CNS Complications
Masayuki Amano et al.
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Amino-acid inserts of HIV-1 capsid (CA) induce CA degradation and abrogate viral infectivity: Insights for the dynamics and mechanisms of HIV-1 CA decomposition
Masayuki Amano et al.
SCIENTIFIC REPORTS (2019)
A highly potent long-acting small-molecule HIV-1 capsid inhibitor with efficacy in a humanized mouse model
Stephen R. Yant et al.
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Toward the unravelling of HIV: Host cell factors involved in HIV-1 core uncoating
Daniel J. Rawle et al.
PLOS PATHOGENS (2018)
Early cytoplasmic uncoating is associated with infectivity of HIV-1
Joao I. Mamede et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)
Survival of HIV-positive patients starting antiretroviral therapy between 1996 and 2013: a collaborative analysis of cohort studies
Adam Trickey et al.
LANCET HIV (2017)
Interventions to improve adherence to antiretroviral therapy: a systematic review and network meta-analysis
Steve Kanters et al.
LANCET HIV (2017)
GRL-09510, a Unique P2-Crown-Tetrahydrofuranylurethane-Containing HIV-1 Protease Inhibitor, Maintains Its Favorable Antiviral Activity against Highly-Drug-Resistant HIV-1 Variants in vitro
Masayuki Amano et al.
SCIENTIFIC REPORTS (2017)
Ebselen, a Small-Molecule Capsid Inhibitor of HIV-1 Replication
Suzie Thenin-Houssier et al.
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The structure and flexibility of conical HIV-1 capsids determined within intact virions
Simone Mattei et al.
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HIV-1 capsid: the multifaceted key player in HIV-1 infection
Edward M. Campbell et al.
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X-ray crystal structures of native HIV-1 capsid protein reveal conformational variability
Anna T. Gres et al.
SCIENCE (2015)
Impact on life expectancy of HIV-1 positive individuals of CD4+ cell count and viral load response to antiretroviral therapy
Margaret T. May et al.
AIDS (2014)
Dimerization of HIV-1 protease occurs through two steps relating to the mechanism of protease dimerization inhibition by darunavir
Hironori Hayashi et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
Host Cofactors and Pharmacologic Ligands Share an Essential Interface in HIV-1 Capsid That Is Lost upon Disassembly
Amanda J. Price et al.
PLOS PATHOGENS (2014)
Novel Inhibitor Binding Site Discovery on HIV-1 Capsid N-Terminal Domain by NMR and X-ray Crystallography
Nathalie Goudreau et al.
ACS CHEMICAL BIOLOGY (2013)
Inhibiting Early-Stage Events in HIV-1 Replication by Small-Molecule Targeting of the HIV-1 Capsid
Sandhya Kortagere et al.
JOURNAL OF VIROLOGY (2012)
Distinct Effects of Two HIV-1 Capsid Assembly Inhibitor Families That Bind the Same Site within the N-Terminal Domain of the Viral CA Protein
Christopher T. Lemke et al.
JOURNAL OF VIROLOGY (2012)
HIV Capsid is a Tractable Target for Small Molecule Therapeutic Intervention
Wade S. Blair et al.
PLOS PATHOGENS (2010)
Jalview Version 2-a multiple sequence alignment editor and analysis workbench
Andrew M. Waterhouse et al.
BIOINFORMATICS (2009)
X-Ray Structures of the Hexameric Building Block of the HIV Capsid
Owen Pornillos et al.
CELL (2009)
Active site remodeling switches HIV specificity of antiretroviral TRIMCyp
Amanda J. Price et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2009)
Involvement of the second extracellular loop and transmembrane residues of CCR5 in inhibitor binding and HIV-1 fusion: Insights into the mechanism of allosteric inhibition
Kenji Maeda et al.
JOURNAL OF MOLECULAR BIOLOGY (2008)
Structure of the antiviral assembly inhibitor CAP-1 complex with the HIV-1CA protein
Brian N. Kelly et al.
JOURNAL OF MOLECULAR BIOLOGY (2007)
HIV-1 DNA Flap formation promotes uncoating of the pre-integration complex at the nuclear pore
Nathalie J. Arhel et al.
EMBO JOURNAL (2007)
A novel bis-tetrahydrofuranylurethane-containing nonpeptidic protease inhibitor (PI), GRL-98065, is potent against multiple-PI-resistant human immunodeficiency virus in vitro
Masayuki Amano et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2007)
The use of differential scanning fluorimetry to detect ligand interactions that promote protein stability
Frank H. Niesen et al.
NATURE PROTOCOLS (2007)
Investigation of N-terminal domain charged residues on the assembly and stability of HIV-1CA
CC Douglas et al.
BIOCHEMISTRY (2004)
Novel bis-tetrahydrofuranylurethane-containin nonpeptidic protease inhibitor (PI) UIC-94017 (TMC114) with potent activity against multi-PI-resistant human immunodeficiency virus in vitro
Y Koh et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2003)
Kinetic analysis of the role of intersubunit interactions in human immunodeficiency virus type 1 capsid protein assembly in vitro
J Lanman et al.
JOURNAL OF VIROLOGY (2002)