A rapid and reliable liquid chromatography/mass spectrometry method for SARS-CoV-2 analysis from gargle solutions and saliva

Article Infectious Diseases

Comparative evaluation of nasopharyngeal swab and saliva specimens for the molecular detection of SARS-CoV-2 RNA in Japanese patients with COVID-19

Daisuke Sakanashi et al.

Summary: The study suggests that saliva could potentially serve as an effective alternative specimen for SARS-CoV-2 RNA detection, especially in situations of shortage of personal protective equipment and specimen sampling tools.

JOURNAL OF INFECTION AND CHEMOTHERAPY (2021)

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Article Virology

Evaluation of a SARS-CoV-2 rapid antigen test: Potential to help reduce community spread?

Tuna Toptan et al.

Summary: The study evaluated the sensitivity and specificity of a newly licensed rapid antigen test for SARS-CoV-2, showing its effectiveness in detecting infectious patients. The antigen test was found to have no cross-reactivity against other common respiratory viruses and demonstrated reliable performance.

JOURNAL OF CLINICAL VIROLOGY (2021)

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Article Chemistry, Multidisciplinary

Cov-MS: A Community-Based Template Assay for Mass-Spectrometry-Based Protein Detection in SARS-CoV-2 Patients

Bart Van Puyvelde et al.

Summary: The rapid spread of COVID-19 is attributed to rising population density and global mobility, making accurate monitoring of the disease essential for policy responses. The current reliance on RT-PCR for diagnosis has limitations due to reagent shortages, prompting the development of an alternative test using mass spectrometry to detect SARS-CoV-2 proteins. The Cov-MS consortium and Digital Incubator were established to enhance the applicability and accessibility of this new diagnostic approach.

JACS AU (2021)

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Article Biochemical Research Methods