Dark-field microscopic real-time monitoring the growth of Au on Cu2O nanocubes for ultra-sensitive glucose detection

Nanoparticle plasmon scattering can provide real-time imaging information on the formation pro-cess of noble metal-based nanomaterials. Due to the synergistic effect of the interface between metal and oxide supporting pores, metal nanoparticles (NPs), especially Au NPs, generally exhibit higher cat-alytic activity on oxide carriers than single-component NPs. Here, we use the dark field scattering mi-croscope to in situ monitor the growth of Au on Cu2O surface by oxidation-reduction reactions and the nanostructures could be precisely controlled via the scattering signal. The prepared Cu2O/Au nano-composite has a higher electrocatalytic activity toward Glucose. When being used as a potential biosensor for nonenzyme glucose detection, excellent performance, such as high sensitivity with a detection limit of 4 mM, high selectivity and outstanding stability, was obtained. The scattering imaging strategy is a convenient and universal approach in controllable synthesis of plasmonic heterostructures, and leads to the improvement of electrocatalysts in biosensing. (C) 2021 Elsevier B.V. All rights reserved.

Automated summary

Nanoparticle plasmon scattering provides real-time imaging information on the formation process of noble metal-based nanomaterials. Metal nanoparticles generally exhibit higher catalytic activity on oxide carriers due to the synergistic effect of the interface between metal and oxide supporting pores. The prepared Cu2O/Au nano-composite shows higher electrocatalytic activity towards Glucose and can be conveniently controlled using scattering imaging strategy.