期刊
AMERICAN JOURNAL OF OPHTHALMOLOGY
卷 235, 期 -, 页码 197-203出版社
ELSEVIER SCIENCE INC
DOI: 10.1016/j.ajo.2021.09.009
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资金
- JSPS KAKENHI [JP20K18349]
This retrospective, cross-sectional study aimed to investigate the clinical factors related to the presence of loculation of fluid (LOF) in central serous chorioretinopathy (CSC). The study found that a thicker choroid and thicker sclera were associated with the presence of LOF in CSC. Age, sex, subfoveal choroidal thickness (SCT), and scleral thickness were also found to be related to LOF.
PURPOSE: To elucidate clinical factors related to the presence of loculation of fluid (LOF) in the posterior choroid in central serous chorioretinopathy (CSC). DESIGN: Retrospective, cross-sectional study. METHODS: This single-center study included 158 eyes from 158 patients with CSC who were classified into LOF and non-LOF groups. The groups were compared for age, sex, spherical equivalent, axial length, subfoveal choroidal thickness (SCT), and scleral thickness. Using swept-source optical coherence tomography (OCT), we determined the presence of LOF based on B-scan and en face images. Scleral thickness was measured 6 mm posterior to the scleral spur in 4 directions using anterior segment OCT. RESULTS: The 158 eyes were classified into 98 eyes in the LOF group and 60 eyes in the non-LOF group. In univariable analyses, the LOF group was younger ( P = .01) and had a higher male ratio (P = .03) and greater SCT ( P < .001) than the non-LOF group. All scleral thicknesses at the superior, temporal, inferior, and nasal points were greater in the LOF group than in the non-LOF group (426.2 vs 395.1 mu m, 445.7 vs 414.9 mu m, 459.2 vs 428.8 mu m, 445.4 vs 414.3 mu m, all P < .05). Multivariable analyses found that SCT (odds ratio [OR] 1.02, 95% CI 1.01-1.02, P < .001) and mean scleral thickness (OR 1.02, 95% CI 1.02-1.03, P = .002) were significantly associated with the presence of LOF. CONCLUSION: A thick choroid and thick sclera appeared to be related to the presence of LOF in CSC. (C) 2021 The Author(s). Published by Elsevier Inc.
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