4.6 Review

Pathophysiology and Management of Hyperoxaluria and Oxalate Nephropathy: A Review

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Review Urology & Nephrology

Pathophysiology and Treatment of Enteric Hyperoxaluria

Celeste Witting et al.

Summary: Enteric hyperoxaluria, a unique condition caused by gastrointestinal disorders, can lead to kidney stones and even kidney failure. Current treatments involve correcting underlying gastrointestinal issues, modifying diet, and using calcium salts to bind oxalate, but there is still a lack of clinical evidence regarding their efficacy. Further research is necessary to understand the risk factors for adverse outcomes and evaluate the long-term effectiveness of existing treatments, as well as develop new therapeutic approaches.

CLINICAL JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2021)

Article Transplantation

Effects of Oxalobacter formigenes in subjects with primary hyperoxaluria Type 1 and end-stage renal disease: a Phase II study

Bernd Hoppe et al.

Summary: In PH1 ESRD patients, long-term administration of OC5 was found to significantly reduce Pox concentrations, improve or stabilize cardiac function and clinical status, without increasing dialysis frequency. OC5 was safe and well-tolerated, showing promising results for potential clinical impact.

NEPHROLOGY DIALYSIS TRANSPLANTATION (2021)

Article Transplantation

Subsequent urinary stone events are predicted by the magnitude of urinary oxalate excretion in enteric hyperoxaluria

Matthew R. D'Costa et al.

Summary: This study investigated the relationship between urinary oxalate excretion and kidney stone events in patients with enteric hyperoxaluria, finding that higher UOx levels were associated with an increased risk of kidney stones, suggesting that strategies to reduce UOx may be beneficial in this patient group.

NEPHROLOGY DIALYSIS TRANSPLANTATION (2021)

Review Urology & Nephrology

Classification of Stones According to Michel Daudon: A Narrative Review

Mariela Corrales et al.

Summary: Morphoconstitutional analysis of urinary stones is crucial in assessing patients with urolithiasis, as it helps identify the type, composition, and potential causes of stones. Through microscopic examination and physical analysis, information on the morphology and constitution of stones can be obtained, providing insights into the primary etiological factors of stone formation.

EUROPEAN UROLOGY FOCUS (2021)

Article Medicine, General & Internal

Lumasiran, an RNAi Therapeutic for Primary Hyperoxaluria Type 1

Sander F. Garrelfs et al.

Summary: Primary hyperoxaluria type 1 is a rare genetic disease caused by hepatic overproduction of oxalate, leading to kidney stones, nephrocalcinosis, kidney failure, and systemic oxalosis. This trial tested the efficacy of lumasiran, an RNAi therapeutic agent, in reducing hepatic oxalate production. The results showed that lumasiran significantly reduced urinary oxalate excretion, alleviating the cause of kidney failure in PH1 patients.

NEW ENGLAND JOURNAL OF MEDICINE (2021)

Article Urology & Nephrology

Kidney oxalate crystal deposition in adult patients: A relatively common finding

Yihe Yang et al.

CLINICAL NEPHROLOGY (2020)

Editorial Material Urology & Nephrology

Acute renal failure and a rejuvenating powder - Vitamin C-induced oxalate nephropathy

Pauline Borceux et al.

KIDNEY INTERNATIONAL (2020)

Article Medical Laboratory Technology

A diagnostician's field guide to crystalline nephropathies

L. Nicholas Cossey et al.

SEMINARS IN DIAGNOSTIC PATHOLOGY (2020)

Article Urology & Nephrology

Perturbations of the Gut Microbiome and Metabolome in Children with Calcium Oxalate Kidney Stone Disease

Michelle R. Denburg et al.

JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2020)

Article Urology & Nephrology

Etiologies, Clinical Features, and Outcome of Oxalate Nephropathy

Benoit Buysschaert et al.

KIDNEY INTERNATIONAL REPORTS (2020)

Article Urology & Nephrology

Enteric Oxalate Secretion Mediated by Slc26a6 Defends against Hyperoxalemia in Murine Models of Chronic Kidney Disease

Laura I. Neumeier et al.

JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2020)

Article Urology & Nephrology

Assessment of Plasma Oxalate Concentration in Patients With CKD

Anja Pfau et al.

KIDNEY INTERNATIONAL REPORTS (2020)

Article Urology & Nephrology

ALLN-177, oral enzyme therapy for hyperoxaluria

James E. Lingeman et al.

INTERNATIONAL UROLOGY AND NEPHROLOGY (2019)

Article Medicine, General & Internal

Association of Urinary Oxalate Excretion With the Risk of Chronic Kidney Disease Progression

Sushrut S. Waikar et al.

JAMA INTERNAL MEDICINE (2019)

Review Urology & Nephrology

Urinary oxalate as a potential mediator of kidney disease in diabetes mellitus and obesity

Orhan Efe et al.

CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION (2019)

Article Gastroenterology & Hepatology

Enhanced gastrointestinal passive paracellular permeability contributes to the obesity-associated hyperoxaluria

Mohamed Bashir et al.

AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2019)

Editorial Material Urology & Nephrology

Unraveling the mechanisms of obesity-induced hyperoxaluria

Khashayar Sakhaee

KIDNEY INTERNATIONAL (2018)

Review Urology & Nephrology

Secondary Oxalate Nephropathy: A Systematic Review

Nuttha Lumlertgul et al.

KIDNEY INTERNATIONAL REPORTS (2018)

Review Urology & Nephrology

Progress in Understanding the Genetics of Calcium-Containing Nephrolithiasis

John A. Sayer

JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2017)

Article Medicine, General & Internal

Enteric hyperoxaluria in chronic pancreatitis

Nathalie Demoulin et al.

MEDICINE (2017)

Review Urology & Nephrology

Crystal nephropathies: mechanisms of crystal-induced kidney injury

Shrikant R. Mulay et al.

NATURE REVIEWS NEPHROLOGY (2017)

Article Surgery

Oxalobacter formigenes colonization normalizes oxalate excretion in a gastric bypass model of hyperoxaluria

Benjamin K. Canales et al.

SURGERY FOR OBESITY AND RELATED DISEASES (2017)

Review Transplantation

Enteric hyperoxaluria: an important cause of end-stage kidney disease

Lama Nazzal et al.

NEPHROLOGY DIALYSIS TRANSPLANTATION (2016)

Review Urology & Nephrology

The management of patients with enteric hyperoxaluria

John R. Asplin

UROLITHIASIS (2016)

Review Urology & Nephrology

Oxalate, inflammasome, and progression of kidney disease

Theresa Ermer et al.

CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION (2016)

Article Endocrinology & Metabolism

Weight loss at a high cost: Orlistat-induced late-onset severe kidney disease

B. Buysschaert et al.

DIABETES & METABOLISM (2016)

Article Urology & Nephrology

An NLRP3-specific inflammasome inhibitor attenuates crystal-induced kidney fibrosis in mice

Isis Ludwig-Portugall et al.

KIDNEY INTERNATIONAL (2016)

Article Medicine, Research & Experimental

Calcium oxalate crystals induce renal inflammation by NLRP3-mediated IL-1 beta secretion

Shrikant R. Mulay et al.

JOURNAL OF CLINICAL INVESTIGATION (2013)

Review Medicine, General & Internal

Primary Hyperoxaluria

Pierre Cochat et al.

NEW ENGLAND JOURNAL OF MEDICINE (2013)

Article Cell Biology

Cholinergic signaling inhibits oxalate transport by human intestinal T84 cells

Hatim A. Hassan et al.

AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2012)

Review Urology & Nephrology

An update on primary hyperoxaluria

Bernd Hoppe

NATURE REVIEWS NEPHROLOGY (2012)

Article Urology & Nephrology

Oxalate Nephropathy Associated with Chronic Pancreatitis

Claire Cartery et al.

CLINICAL JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2011)

Article Urology & Nephrology

An easily overlooked iatrogenic cause of renal failure

N. Demoulin et al.

CLINICAL NEPHROLOGY (2011)

Review Urology & Nephrology

Nephrocalcinosis and urolithiasis in children

Sandra Habbig et al.

KIDNEY INTERNATIONAL (2011)

Review Urology & Nephrology

Hyperoxaluria: a gut-kidney axis?

Stef Robijn et al.

KIDNEY INTERNATIONAL (2011)

Article Physiology

Evidence for net renal tubule oxalate secretion in patients with calcium kidney stones

Kristin J. Bergsland et al.

AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY (2011)

Article Medicine, Research & Experimental

Urolithiasis and hepatotoxicity are linked to the anion transporter Sat1 in mice

Paul A. Dawson et al.

JOURNAL OF CLINICAL INVESTIGATION (2010)

Article Medicine, Research & Experimental

Liquid chromatography-tandem mass spectrometry determination of oxalate in spot urine

Katja B. P. Elgstoen et al.

SCANDINAVIAN JOURNAL OF CLINICAL & LABORATORY INVESTIGATION (2010)

Article Transplantation

Oxalate deposits in biopsies from native and transplanted kidneys, and impact on graft function

Serena M. Bagnasco et al.

NEPHROLOGY DIALYSIS TRANSPLANTATION (2009)

Article Urology & Nephrology

Oxalate Nephropathy Complicating Roux-en-Y Gastric Bypass: An Underrecognized Cause of Irreversible Renal Failure

Samih H. Nasr et al.

CLINICAL JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2008)

Review Urology & Nephrology

Nephrolithiasis as a systemic disorder

Khashayar Sakhaee

CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION (2008)

Article Cell Biology

Regulation of anion exchanger Slc26a6 by protein kinase C

Hatim A. Hassan et al.

AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2007)

Article Urology & Nephrology

Oxalobacter sp reduces urinary oxalate excretion by promoting enteric oxalate secretion

M Hatch et al.

KIDNEY INTERNATIONAL (2006)

Review Neurosciences

Purinergic regulation of epithelial transport

RE Bucheimer et al.

JOURNAL OF PHYSIOLOGY-LONDON (2004)

Article Biochemistry & Molecular Biology

Diagnostic and therapeutic approaches in patients with secondary hyperoxaluria

B Hoppe et al.

FRONTIERS IN BIOSCIENCE-LANDMARK (2003)

Article Urology & Nephrology

Contribution of dietary oxalate to urinary oxalate excretion

RP Holmes et al.

KIDNEY INTERNATIONAL (2001)

Article Urology & Nephrology

Estimation of the oxalate content of foods and daily oxalate intake

RP Holmes et al.

KIDNEY INTERNATIONAL (2000)