4.5 Article

Decontamination of disposable respirators for reuse in a pandemic employing in-situ-generated peracetic acid

期刊

AMERICAN JOURNAL OF INFECTION CONTROL
卷 50, 期 4, 页码 420-426

出版社

MOSBY-ELSEVIER
DOI: 10.1016/j.ajic.2021.09.017

关键词

Decontamination; FFP; Hydrogen peroxide; Acetic Acid; COVID-19

资金

  1. Federal Institute for Drugs and Medical Devices (Bundesinstitut fur Arzneimittel und Medizinprodukte, BfArM, Bonn) [V-2020.3/68502/2020]
  2. Federal Ministry of Health (Bundesministerium fur Gesundheit, BMG)

向作者/读者索取更多资源

This study aimed to develop a simple, inexpensive, and ecological method for decontamination of disposable FFPs while preserving filtration efficiency and material integrity. The results showed that immersion in a 6% acetic acid and 6% hydrogen peroxide solution for 30 minutes completely eliminated contaminants without compromising the performance of FFPs.
Background: During shortages of filtering face pieces (FFP) in a pandemic, it is necessary to implement a method for safe reuse or extended use. Our aim was to develop a simple, inexpensive and ecological method for decontamination of disposable FFPs that preserves filtration efficiency and material integrity.Material and methods: Contamination of FFPs (3M Aura 9320+) with SARS-CoV-2 (1.15 x 10(4) PFUs), Enterococcus faecium (> 10(6) CFUs), and physiological nasopharyngeal flora was performed prior to decontamination by submersion in a solution of 6 % acetic acid and 6 % hydrogen peroxide (6%AA/6%HP solution) over 30 minutes. Material integrity was assessed by testing the filtering efficiency, loss of fit and employing electron microscopy.Results and Discussion: Decontamination with the 6%AA/6%HP solution resulted in the complete elimination of SARS-CoV-2, E. faecium and physiological nasopharyngeal flora. Material characterization post-treatment showed neither critical material degradation, loss of fit or reduction of filtration efficiency. Electron microscopy revealed no damage to the fibers, and the rubber bands' elasticity was not affected by the decontamination procedure. No concerning residuals of the decontamination procedure were found. Conclusion: The simple application and widespread availability of 6%AA/6%HP solution for decontaminating disposable FFPs make this solution globally viable, including developing and third world countries.(c) 2021 The Author(s). Published by Elsevier Inc. on behalf of Association for Professionals in Infection Control and Epidemiology, Inc.

作者

我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。

评论

主要评分

4.5
评分不足

次要评分

新颖性
-
重要性
-
科学严谨性
-
评价这篇论文

推荐

暂无数据
暂无数据