期刊
AMERICAN JOURNAL OF INFECTION CONTROL
卷 50, 期 4, 页码 420-426出版社
MOSBY-ELSEVIER
DOI: 10.1016/j.ajic.2021.09.017
关键词
Decontamination; FFP; Hydrogen peroxide; Acetic Acid; COVID-19
资金
- Federal Institute for Drugs and Medical Devices (Bundesinstitut fur Arzneimittel und Medizinprodukte, BfArM, Bonn) [V-2020.3/68502/2020]
- Federal Ministry of Health (Bundesministerium fur Gesundheit, BMG)
This study aimed to develop a simple, inexpensive, and ecological method for decontamination of disposable FFPs while preserving filtration efficiency and material integrity. The results showed that immersion in a 6% acetic acid and 6% hydrogen peroxide solution for 30 minutes completely eliminated contaminants without compromising the performance of FFPs.
Background: During shortages of filtering face pieces (FFP) in a pandemic, it is necessary to implement a method for safe reuse or extended use. Our aim was to develop a simple, inexpensive and ecological method for decontamination of disposable FFPs that preserves filtration efficiency and material integrity.Material and methods: Contamination of FFPs (3M Aura 9320+) with SARS-CoV-2 (1.15 x 10(4) PFUs), Enterococcus faecium (> 10(6) CFUs), and physiological nasopharyngeal flora was performed prior to decontamination by submersion in a solution of 6 % acetic acid and 6 % hydrogen peroxide (6%AA/6%HP solution) over 30 minutes. Material integrity was assessed by testing the filtering efficiency, loss of fit and employing electron microscopy.Results and Discussion: Decontamination with the 6%AA/6%HP solution resulted in the complete elimination of SARS-CoV-2, E. faecium and physiological nasopharyngeal flora. Material characterization post-treatment showed neither critical material degradation, loss of fit or reduction of filtration efficiency. Electron microscopy revealed no damage to the fibers, and the rubber bands' elasticity was not affected by the decontamination procedure. No concerning residuals of the decontamination procedure were found. Conclusion: The simple application and widespread availability of 6%AA/6%HP solution for decontaminating disposable FFPs make this solution globally viable, including developing and third world countries.(c) 2021 The Author(s). Published by Elsevier Inc. on behalf of Association for Professionals in Infection Control and Epidemiology, Inc.
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