期刊
AGING-US
卷 13, 期 12, 页码 15898-+出版社
IMPACT JOURNALS LLC
DOI: 10.18632/aging.203213
关键词
dementia; prevention; lifestyle; feasibility; randomized controlled trial
资金
- Korea Health Technology R&D Project through the Korea Health Industry Development Institute (KHIDI) - Ministry of Health and Welfare, Republic of Korea [HI18C0479, HI20C0253]
- National Research Foundation of Korea (NRF) - Ministry of Science and ICT, Republic of Korea [2018R1A2A2A15023219, NRF-2018M3C7A1056293, 2019R1A5A2026045, NRF-2019R1F1A1059660, NRF-2019R1F1A1062085, NRF-2020M3E5D2A01084721]
The study assessed the feasibility of a multidomain intervention tailored to the Korean context. Both facility-based MI and home-based MI showed good retention rates, adherence to the intervention, and significant improvements in the RBANS total scale index scores.
We aimed to evaluate the feasibility of multidomain intervention (MI) tailored to the Korean context. In an outcome assessor-blinded, randomized controlled trial, participants without dementia and with one or more modifiable dementia risk factors, aged 60-79 years, were randomly assigned to the facility-based MI (FMI; n=51), the home-based MI (HMI; n=51), or the control group receiving general health advice (n=50). The 24-week intervention comprised vascular risk management, cognitive training, social activity, physical exercise, nutrition guidance, and motivational enhancement. The FMI participants performed all intervention programs at a facility three times a week. The HMI participants performed some programs at a facility once every 1-2 weeks and performed others at home. The primary outcome was feasibility measured through retention, adherence, and at least no differences from the control group in the Repeatable Battery for the Assessment of Neuropsychological Status (RBANS). In the FMI and HMI groups, the retention rates were 88.2% and 96.1%, and adherence to the intervention was 94.5% and 96.8%, respectively. The RBANS total scale index score improved significantly in the FMI (5.46 +/- 7.50, P = 0.004) and HMI (5.50 +/- 8.14, P = 0.004) groups compared to the control group (-0.74 +/- 11.51). The FMI and HMI are feasible and there are indicators of efficacy.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据