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Induction of the Mitochondrial NDUFA4L2 Protein by HIF-1α Decreases Oxygen Consumption by Inhibiting Complex I Activity
Daniel Tello et al.
CELL METABOLISM (2011)
Neurophysiological evidence for cognitive and brain functional adaptation in adolescents living at high altitude
Cassandra Richardson et al.
CLINICAL NEUROPHYSIOLOGY (2011)
Intermittent hypoxia conditioning prevents endothelial dysfunction and improves nitric oxide storage in spontaneously hypertensive rats
Eugenia B. Manukhina et al.
EXPERIMENTAL BIOLOGY AND MEDICINE (2011)
Genome sequencing reveals insights into physiology and longevity of the naked mole rat
Eun Bae Kim et al.
NATURE (2011)
Mechanisms of Disease: Hypoxia and Inflammation.
Holger K. Eltzschig et al.
NEW ENGLAND JOURNAL OF MEDICINE (2011)
The hypoxia-inducible factor HIF-1 functions as both a positive and negative modulator of aging
Scott F. Leiser et al.
BIOLOGICAL CHEMISTRY (2010)
Melatonin reduces hippocampal β-amyloid generation in rats exposed to chronic intermittent hypoxia
Kwong-Man Ng et al.
BRAIN RESEARCH (2010)
Cognitive function in COPD
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EUROPEAN RESPIRATORY JOURNAL (2010)
S100B Profiles and Cognitive Function at High Altitude
Henrik Bjursten et al.
HIGH ALTITUDE MEDICINE & BIOLOGY (2010)
Hypoxia-inducible factor 1: a new hope to counteract neurodegeneration?
Sonia C. Correia et al.
JOURNAL OF NEUROCHEMISTRY (2010)
Intermittent Hypoxia Promotes Hippocampal Neurogenesis and Produces Antidepressant-Like Effects in Adult Rats
Xin-Hong Zhu et al.
JOURNAL OF NEUROSCIENCE (2010)
Hypoxic Preconditioning Failure in Aging Hippocampal Neurons: Impaired Gene Expression and Rescue With Intracellular Calcium Chelation
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JOURNAL OF NEUROSCIENCE RESEARCH (2010)
Protein Misfolding Induces Hypoxic Preconditioning via a Subset of the Unfolded Protein Response Machinery
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MOLECULAR AND CELLULAR BIOLOGY (2010)
Brain-derived neurotrophic factor rescues and prevents chronic intermittent hypoxia-induced impairment of hippocampal long-term synaptic plasticity
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NEUROBIOLOGY OF DISEASE (2010)
Nitric Oxide Signaling in Brain Function, Dysfunction, and Dementia
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NEUROSCIENTIST (2010)
Adaptation to intermittent hypoxia restricts nitric oxide overproduction and prevents beta-amyloid toxicity in rat brain
Anna V. Goryacheva et al.
NITRIC OXIDE-BIOLOGY AND CHEMISTRY (2010)
The Ventilatory Response to Hypoxia in Mammals: Mechanisms, Measurement, and Analysis
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PHYSIOLOGICAL REVIEWS (2010)
Hypoxia and Neurodegeneration
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HYPOXIA AND CONSEQUENCES FROM MOLECULE TO MALADY (2009)
Characteristic Changes in Brain Electrical Activity Due to Chronic Hypoxia in Patients with Obstructive Sleep Apnea Syndrome (OSAS): A Combined EEG Study Using LORETA and Omega Complexity
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BRAIN TOPOGRAPHY (2009)
Extension of Drosophila Life Span by RNAi of the Mitochondrial Respiratory Chain
Jeffrey M. Copeland et al.
CURRENT BIOLOGY (2009)
Is there more to aging than mitochondrial DNA and reactive oxygen species?
Mikhail F. Alexeyev
FEBS JOURNAL (2009)
Interval hypoxic training improves autonomic cardiovascular and respiratory control in patients with mild chronic obstructive pulmonary disease
Thomas Haider et al.
JOURNAL OF HYPERTENSION (2009)
Preconditioning and tolerance against cerebral ischaemia: from experimental strategies to clinical use
Ulrich Dirnagl et al.
LANCET NEUROLOGY (2009)
The cerebral effects of ascent to high altitudes
Mark H. Wilson et al.
LANCET NEUROLOGY (2009)
Generating specificity and diversity in the transcriptional response to hypoxia
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NATURE REVIEWS GENETICS (2009)
Proteasomal Regulation of the Hypoxic Response Modulates Aging in C-elegans
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SCIENCE (2009)
Cognitive Assessment of a Trekking Expedition to 5100 m: A Comparison of Computerized and Written Testing Methods
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WILDERNESS & ENVIRONMENTAL MEDICINE (2009)
Regulation of haeme oxygenase-1 for treatment of neuroinflammation and brain disorders
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BRITISH JOURNAL OF PHARMACOLOGY (2008)
Role of Nitric Oxide in Prevention of Cognitive Disorders in Neurodegenerative Brain Injuries in Rats
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BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE (2008)
Intermittent hypoxia: Cause of or therapy for systemic hypertension?
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EXPERIMENTAL BIOLOGY AND MEDICINE (2008)
Early mitochondrial dysfunction in long-lived Mclk1+/- mice
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JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Serum brain-derived neurotrophic factor is associated with cognitive function in healthy older adults
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JOURNAL OF GERIATRIC PSYCHIATRY AND NEUROLOGY (2008)
Mitochondrial dysfunction as a cause of ageing
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JOURNAL OF INTERNAL MEDICINE (2008)
Oxygen sensing by metazoans: The central role of the HIF hydroxylase pathway
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MOLECULAR CELL (2008)
The insulin paradox: aging, proteotoxicity and neurodegeneration
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NATURE REVIEWS NEUROSCIENCE (2008)
Effects of hypoxia and oxidative stress on expression of neprilysin in human neuroblastoma cells and rat cortical neurones and astrocytes
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NEUROCHEMICAL RESEARCH (2007)
Reducing endogenous tau ameliorates amyloid β-induced deficits in an Alzheimer's disease mouse model
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SCIENCE (2007)
Increased longevity and refractoriness to Ca2+-dependent neurodegeneration in Surf1 knockout mice
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HUMAN MOLECULAR GENETICS (2007)
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AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2007)
Reoxygenation-specific activation of the antioxidant transcription factor Nrf2 mediates cytoprotective gene expression in ischemia-reperfusion injury
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FASEB JOURNAL (2006)
Function of the rat carotid body chemoreceptors in ageing
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JOURNAL OF NEUROCHEMISTRY (2006)
Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases
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NATURE (2006)
Parkinsonism and personality changes following an acute hypoxic insult during mountaineering
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MOVEMENT DISORDERS (2006)
Is there a molecular connection between hypoxia and aging?
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EXPERIMENTAL GERONTOLOGY (2006)
Role of nitric oxide in cardiovascular adaptation to intermittent hypoxia
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EXPERIMENTAL BIOLOGY AND MEDICINE (2006)
Obesity and vascular risk factors at midlife and the risk of dementia and Alzheimer disease
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ARCHIVES OF NEUROLOGY (2005)
HIF-1α cytoplasmic accumulation is associated with cell death in old rat cerebral cortex exposed to intermittent hypoxia
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AGING CELL (2005)
Effect of exercise on cerebral perfusion in humans at high altitude
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JOURNAL OF APPLIED PHYSIOLOGY (2005)
Oxygen and life span:: chronic hypoxia as a model for studying HIF-1α, VEGF and NOS during aging
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RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY (2005)
Effects of cable car ascent to 2700 meters on mean EEG frequency and event-related desynchronization (ERD)
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WIENER MEDIZINISCHE WOCHENSCHRIFT (2005)
Aging of the respiratory system: Impact on pulmonary function tests and adaptation to exertion
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CLINICS IN CHEST MEDICINE (2005)
Hypoxia of sleep apnoea: cardiopulmonary and cerebral changes after intermittent hypoxia in rats
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RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY (2004)
Intermittent hypoxia increases exercise tolerance in elderly men with and without coronary artery disease
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INTERNATIONAL JOURNAL OF CARDIOLOGY (2004)
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JOURNAL OF EXPERIMENTAL BIOLOGY (2004)
Mitochondrial oxidative phosphorylation is defective in the long-lived mutant clk-1
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JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Carotid body as a model for aging studies: is there a link between oxygen and aging?
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JOURNAL OF APPLIED PHYSIOLOGY (2003)
Increased susceptibility to intermittent hypoxia in aging rats: changes in proteasomal activity, neuronal apoptosis and spatial function
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JOURNAL OF NEUROCHEMISTRY (2003)
Analysis of the effect of aging on the response to hypoxia by cDNA microarray
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MECHANISMS OF AGEING AND DEVELOPMENT (2003)
Verbal free recall in high altitude: Proper names vs common names
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CORTEX (2003)
Obstructive sleep apnoea syndrome - an oxidative stress disorder
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SLEEP MEDICINE REVIEWS (2003)
A systematic RNAi screen identifies a critical role for mitochondria in C-elegans longevity
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NATURE GENETICS (2003)
Aging abolishes the cardioprotective effect of combination heat shock and hypoxic preconditioning in reperfused rat hearts
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BASIC RESEARCH IN CARDIOLOGY (2002)
Normobaric hypoxia induces tolerance to focal permanent cerebral ischemia in association with an increased expression of hypoxia-inducible factor-1 and its target genes, erythropoietin and VEGF, in the adult mouse brain
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JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM (2002)
Mitochondrial electron transport is a key determinant of life span in Caenorhabditis elegans
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DEVELOPMENTAL CELL (2001)
Current concepts: High-altitude illness.
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NEW ENGLAND JOURNAL OF MEDICINE (2001)
Acute hypoxia and hypoxic exercise induce DNA strand breaks and oxidative DNA damage in humans
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FASEB JOURNAL (2001)
Physiological and genomic consequences of intermittent hypoxia -: Invited review:: Physiological and pathophysiological responses to intermittent hypoxia
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JOURNAL OF APPLIED PHYSIOLOGY (2001)
Synucleinopathies - Clinical and pathological implications
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ARCHIVES OF NEUROLOGY (2001)
Expression of hypoxia-inducible factor-1α in the brain of rats during chronic hypoxia
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JOURNAL OF APPLIED PHYSIOLOGY (2000)
Geriatric men at altitude: Hypoxic ventilatory sensitivity and blood dopamine changes
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RESPIRATION (2000)
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