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Prevalence of Sleep Disturbances in Mild Cognitive Impairment and Dementing Disorders: A Multicenter Italian Clinical Cross-Sectional Study on 431 Patients
B. Guarnieri et al.
DEMENTIA AND GERIATRIC COGNITIVE DISORDERS (2012)
Identification of SPARC-like 1 Protein as Part of a Biomarker Panel for Alzheimer's Disease in Cerebrospinal Fluid
Baharak Vafadar-Isfahani et al.
JOURNAL OF ALZHEIMERS DISEASE (2012)
Updated energy budgets for neural computation in the neocortex and cerebellum
Clare Howarth et al.
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM (2012)
Pathophysiology of the neurovascular unit: disease cause or consequence?
Danica B. Stanimirovic et al.
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM (2012)
The chemokine, macrophage inflammatory protein-2γ, reduces the expression of glutamate transporter-1 on astrocytes and increases neuronal sensitivity to glutamate excitotoxicity
Jie Fang et al.
JOURNAL OF NEUROINFLAMMATION (2012)
Early Stage Drug Treatment That Normalizes Proinflammatory Cytokine Production Attenuates Synaptic Dysfunction in a Mouse Model That Exhibits Age-Dependent Progression of Alzheimer's Disease-Related Pathology
Adam D. Bachstetter et al.
JOURNAL OF NEUROSCIENCE (2012)
Targeting Astrocytes Ameliorates Neurologic Changes in a Mouse Model of Alzheimer's Disease
Jennifer L. Furman et al.
JOURNAL OF NEUROSCIENCE (2012)
Genomic Analysis of Reactive Astrogliosis
Jennifer L. Zamanian et al.
JOURNAL OF NEUROSCIENCE (2012)
Evidence for Astrocytosis in Prodromal Alzheimer Disease Provided by 11C-Deuterium-L-Deprenyl: A Multitracer PET Paradigm Combining 11C-Pittsburgh Compound B and 18F-FDG
Stephen F. Carter et al.
JOURNAL OF NUCLEAR MEDICINE (2012)
Regulation of the phosphatase calcineurin by insulin-like growth factor I unveils a key role of astrocytes in Alzheimer's pathology
A. M. Fernandez et al.
MOLECULAR PSYCHIATRY (2012)
Apolipoprotein E controls cerebrovascular integrity via cyclophilin A
Robert D. Bell et al.
NATURE (2012)
Neuroinflammation and Blood-Brain Barrier Changes in Capillary Amyloid Angiopathy
Anna Carrano et al.
NEURODEGENERATIVE DISEASES (2012)
Inhibition of Soluble Tumor Necrosis Factor Ameliorates Synaptic Alterations and Ca2+ Dysregulation in Aged Rats
Diana M. Sama et al.
PLOS ONE (2012)
A Paravascular Pathway Facilitates CSF Flow Through the Brain Parenchyma and the Clearance of Interstitial Solutes, Including Amyloid β
Jeffrey J. Iliff et al.
SCIENCE TRANSLATIONAL MEDICINE (2012)
Disruption of the Sleep-Wake Cycle and Diurnal Fluctuation of Amyloid-β in Mice with Alzheimer's Disease Pathology
Jee Hoon Roh et al.
SCIENCE TRANSLATIONAL MEDICINE (2012)
Spines, Plasticity, and Cognition in Alzheimer's Model Mice
Tara Spires-Jones et al.
NEURAL PLASTICITY (2012)
Vascular β-amyloid and early astrocyte alterations impair cerebrovascular function and cerebral metabolism in transgenic arcAβ mice
Mario Merlini et al.
ACTA NEUROPATHOLOGICA (2011)
Proteolysis of calcineurin is increased in human hippocampus during mild cognitive impairment and is stimulated by oligomeric Abeta in primary cell culture
Hafiz Mohmmad Abdul et al.
AGING CELL (2011)
Cerebral amyloid angiopathy in the elderly
Anand Viswanathan et al.
ANNALS OF NEUROLOGY (2011)
Evidence for a role of dystroglycan regulating the membrane architecture of astroglial endfeet
Susan Noell et al.
EUROPEAN JOURNAL OF NEUROSCIENCE (2011)
Cerebral glucose and lactate consumption during cerebral activation by physical activity in humans
Peter Rasmussen et al.
FASEB JOURNAL (2011)
Response of Transcription Factor NFATc3 to Excitotoxic and Traumatic Brain Insults: Identification of a Subpopulation of Reactive Astrocytes
Maria C. Serrano-Perez et al.
GLIA (2011)
FOXO3a Inhibits TNF-α- and IL-1β-Induced Astrocyte Proliferation: Implication for Reactive Astrogliosis
Min Cui et al.
GLIA (2011)
Impact of Aquaporin-4 Channels on K+ Buffering and Gap Junction Coupling in the Hippocampus
Susan Strohschein et al.
GLIA (2011)
Glial Glutamate Transporters: New Actors in Brain Signaling
Esther Lopez-Bayghen et al.
IUBMB LIFE (2011)
Region- and Age-Specific Changes in Glutamate Transport in the A beta PP23 Mouse Model for Alzheimer's Disease
Anneleen Schallier et al.
JOURNAL OF ALZHEIMERS DISEASE (2011)
Contribution of complement activation pathways to neuropathology differs among mouse models of Alzheimer's disease
Maria I. Fonseca et al.
JOURNAL OF NEUROINFLAMMATION (2011)
In Vivo Evidence for Lactate as a Neuronal Energy Source
Matthias T. Wyss et al.
JOURNAL OF NEUROSCIENCE (2011)
TNF-α potentiates glutamate-induced spinal cord motoneuron death via NF-κB
Laia Tolosa et al.
MOLECULAR AND CELLULAR NEUROSCIENCE (2011)
Central nervous system pericytes in health and disease
Ethan A. Winkler et al.
NATURE NEUROSCIENCE (2011)
Neuronal activity regulates the regional vulnerability to amyloid-β deposition
Adam W. Bero et al.
NATURE NEUROSCIENCE (2011)
Neurovascular pathways to neurodegeneration in Alzheimer's disease and other disorders
Berislav V. Zlokovic
NATURE REVIEWS NEUROSCIENCE (2011)
Brain fuel metabolism, aging, and Alzheimer's disease
Stephen Cunnane et al.
NUTRITION (2011)
Control of excitatory CNS synaptogenesis by astrocyte-secreted proteins Hevin and SPARC
Hakan Kucukdereli et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Synthetic gelatinases inhibitor attenuates electromagnetic pulse-induced blood-brain barrier disruption by inhibiting gelatinases-mediated ZO-1 degradation in rats
Lian-Bo Qiu et al.
TOXICOLOGY (2011)
Amyloid imaging in the differential diagnosis of dementia: review and potential clinical applications
Robert Laforce et al.
ALZHEIMERS RESEARCH & THERAPY (2011)
Decline in mitochondrial bioenergetics and shift to ketogenic profile in brain during reproductive senescence
Jia Yao et al.
BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS (2010)
Changes with Age in the Activities of β-Secretase and the Aβ-Degrading Enzymes Neprilysin, Insulin-Degrading Enzyme and Angiotensin-Converting Enzyme
J. Scott Miners et al.
BRAIN PATHOLOGY (2010)
Potassium Channels and Neurovascular Coupling
Kathryn M. Dunn et al.
CIRCULATION JOURNAL (2010)
Homocysteine is associated with hippocampal and white matter atrophy in older subjects with mild hypertension
Michael J. Firbank et al.
INTERNATIONAL PSYCHOGERIATRICS (2010)
Predominant Enhancement of Glucose Uptake in Astrocytes versus Neurons during Activation of the Somatosensory Cortex
Julien Chuquet et al.
JOURNAL OF NEUROSCIENCE (2010)
Norepinephrine Promotes Microglia to Uptake and Degrade Amyloid β Peptide through Upregulation of Mouse Formyl Peptide Receptor 2 and Induction of Insulin-Degrading Enzyme
Yan Kong et al.
JOURNAL OF NEUROSCIENCE (2010)
Amyloid β Induces the Morphological Neurodegenerative Triad of Spine Loss, Dendritic Simplification, and Neuritic Dystrophies through Calcineurin Activation
Hai-Yan Wu et al.
JOURNAL OF NEUROSCIENCE (2010)
Amyloid-β Aggregates Cause Alterations of Astrocytic Metabolic Phenotype: Impact on Neuronal Viability
Igor Allaman et al.
JOURNAL OF NEUROSCIENCE (2010)
Pericytes regulate the blood-brain barrier
Annika Armulik et al.
NATURE (2010)
Astrocyte phenotype in relation to Alzheimer-type pathology in the ageing brain
J. E. Simpson et al.
NEUROBIOLOGY OF AGING (2010)
A Role for Thrombospondin-1 Deficits in Astrocyte-Mediated Spine and Synaptic Pathology in Down's Syndrome
Octavio Garcia et al.
PLOS ONE (2010)
Astrocytic endfoot Ca2+ and BK channels determine both arteriolar dilation and constriction
Helene Girouard et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Spatial correlation between brain aerobic glycolysis and amyloid-β (Aβ) deposition
Andrei G. Vlassenko et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Decreased Clearance of CNS β-Amyloid in Alzheimer's Disease
Kwasi G. Mawuenyega et al.
SCIENCE (2010)
Where Vascular Meets Neurodegenerative Disease
Julie A. Schneider et al.
STROKE (2010)
Alterations of matrix metalloproteinases in the healthy elderly with increased risk of prodromal Alzheimer's disease
Erik Stomrud et al.
ALZHEIMERS RESEARCH & THERAPY (2010)
Blood lactate is an important energy source for the human brain
Gerrit van Hall et al.
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM (2009)
Long-Term Homeostasis of Extracellular Glutamate in the Rat Cerebral Cortex across Sleep and Waking States
Michael B. Dash et al.
JOURNAL OF NEUROSCIENCE (2009)
Cognitive Decline in Alzheimer's Disease Is Associated with Selective Changes in Calcineurin/NFAT Signaling
Hafiz Mohmmad Abdul et al.
JOURNAL OF NEUROSCIENCE (2009)
Uniquely Hominid Features of Adult Human Astrocytes
Nancy Ann Oberheim et al.
JOURNAL OF NEUROSCIENCE (2009)
Proteomics-Determined Differences in the Concanavalin-A-Fractionated Proteome of Hippocampus and Inferior Parietal Lobule in Subjects with Alzheimer's Disease and Mild Cognitive Impairment: Implications for Progression of AD
Joshua B. Owen et al.
JOURNAL OF PROTEOME RESEARCH (2009)
A new blood-brain barrier model using primary rat brain endothelial cells, pericytes and astrocytes
Shinsuke Nakagawa et al.
NEUROCHEMISTRY INTERNATIONAL (2009)
VASCULAR AMYLOID ALTERS ASTROCYTIC WATER AND POTASSIUM CHANNELS IN MOUSE MODELS AND HUMANS WITH ALZHEIMER'S DISEASE
D. M. Wilcock et al.
NEUROSCIENCE (2009)
Amyloid-β Dynamics Are Regulated by Orexin and the Sleep-Wake Cycle
Jae-Eun Kang et al.
SCIENCE (2009)
Cyclooxygenase-2 inhibition improves amyloid-β-mediated suppression of memory and synaptic plasticity
Linda A. Kotilinek et al.
BRAIN (2008)
Advances in measuring cellular bioenergetics using extracellular flux
David A. Ferrick et al.
DRUG DISCOVERY TODAY (2008)
Interleukin-1β-dependent signaling between astrocytes and neurons depends critically on astrocytic calcineurin/NFAT activity
Michelle A. Sama et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
The inflammatory cytokine, interleukin-1 beta, mediates loss of astroglial glutamate transport and drives excitotoxic motor neuron injury in the spinal cord during acute viral encephalomyelitis
Natalie A. Prow et al.
JOURNAL OF NEUROCHEMISTRY (2008)
Brain metabolism dictates the polarity of astrocyte control over arterioles
Grant R. J. Gordon et al.
NATURE (2008)
Hippocampal hypornetabolism predicts cognitive decline from normal aging
Lisa Mosconi et al.
NEUROBIOLOGY OF AGING (2008)
Aquaporins and cell migration
M. C. Papadopoulos et al.
PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY (2008)
The classical complement cascade mediates CNS synapse elimination
Beth Stevens et al.
CELL (2007)
Glial glutamate transporter 1 regulates the spatial and temporal coding of glutamatergic synaptic transmission in spinal lamina ∥ neurons
H. -R. Weng et al.
NEUROSCIENCE (2007)
The role of glutamate transporters in neurodegenerative diseases and potential opportunities for intervention
Amanda L. Sheldon et al.
NEUROCHEMISTRY INTERNATIONAL (2007)
Conditional knock-out of Kir4.1 leads to glial membrane depolarization, inhibition of potassium and glutamate uptake, and enhanced short-term synaptic Potentiation
Biljana Djukic et al.
JOURNAL OF NEUROSCIENCE (2007)
Calcineurin in reactive astrocytes plays a key role in the interplay between proinflammatory and anti-inflammatory signals
Ana M. Fernandez et al.
JOURNAL OF NEUROSCIENCE (2007)
Brain erythropoietin receptor expression in Alzheimer disease and mild cognitive impairment
Michael I. Assaraf et al.
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2007)
Matrix metalloproteinase-mediated disruption of tight junction proteins in cerebral vessels is reversed by synthetic matrix metalloproteinase inhibitor in focal ischemia in rat
Yi Yang et al.
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM (2007)
Downregulation of Kir4.1 inward rectifying potassium channel subunits by RNAi impairs potassium transfer and glutamate uptake by cultured cortical astrocytes
Y. V. Kucheryavykh et al.
GLIA (2007)
Plasticity of perisynaptic astroglia during synaptogenesis in the mature rat hippocampus
Mark R. Witcher et al.
GLIA (2007)
Calcium signaling in specialized glial cells
Monica R. Metea et al.
GLIA (2006)
Local potassium signaling couples neuronal activity to vasodilation in the brain
Jessica A. Filosa et al.
NATURE NEUROSCIENCE (2006)
Matrix metalloproteinases expressed by astrocytes mediate extracellular amyloid-β peptide catabolism
Ke-Jie Yin et al.
JOURNAL OF NEUROSCIENCE (2006)
Intraneuronal β-amyloid aggregates, neurodegeneration, and neuron loss in transgenic mice with five familial Alzheimer's disease mutations:: Potential factors in amyloid plaque formation
Holly Oakley et al.
JOURNAL OF NEUROSCIENCE (2006)
Competition between glucose and lactate as oxidative energy substrates in both neurons and astrocytes: a comparative NMR study
Anne-Karine Bouzier-Sore et al.
EUROPEAN JOURNAL OF NEUROSCIENCE (2006)
Synaptic scaling mediated by glial TNF-α
D Stellwagen et al.
NATURE (2006)
Ageing and neuronal vulnerability
MP Mattson et al.
NATURE REVIEWS NEUROSCIENCE (2006)
Lack of the Kir4.1 channel subunit abolishes K+ buffering properties of astrocytes in the ventral respiratory group:: Impact on extracellular K+ regulation
C Neusch et al.
JOURNAL OF NEUROPHYSIOLOGY (2006)
Glial heme oxygenase-1 expression in Alzheimer disease and mild cognitive impairment
HM Schipper et al.
NEUROBIOLOGY OF AGING (2006)
Involvement of aquaporin-4 in astroglial cell migration and glial scar formation
S Saadoun et al.
JOURNAL OF CELL SCIENCE (2005)
The interleukin-1 signalling pathway in astrocytes: a key contributor to inflammation in the brain
PN Moynagh
JOURNAL OF ANATOMY (2005)
Modulator effects of interleukin-1β and tumor necrosis factor-α on AMPA-induced excitotoxicity in mouse organotypic hippocampal slice cultures
L Bernardino et al.
JOURNAL OF NEUROSCIENCE (2005)
Inhibition of astroglial nuclear factor κB reduces inflammation and improves functional recovery after spinal cord injury
R Brambilla et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2005)
Calcineurin triggers reactive/inflammatory processes in astrocytes and is upregulated in aging and Alzheimer's models
CM Norris et al.
JOURNAL OF NEUROSCIENCE (2005)
Differential regulation of AMPA receptor and GABA receptor trafficking by tumor necrosis factor-α
D Stellwagen et al.
JOURNAL OF NEUROSCIENCE (2005)
Thrombospondins are astrocyte-secreted proteins that promote CNS synaptogenesis
KS Christopherson et al.
CELL (2005)
Actions of TNF-alpha on glutamatergic synaptic transmission in the central nervous system
M Pickering et al.
EXPERIMENTAL PHYSIOLOGY (2005)
Critical role of calpain-mediated cleavage of calcineurin in excitotoxic neurodegeneration
HY Wu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Calcium transients in astrocyte endfeet cause cerebrovascular constrictions
SJ Mulligan et al.
NATURE (2004)
Tumor necrosis factor (TNF)-mediated neuroprotection against glutamate-induced excitotoxicity is enhanced by N-methyl-D-aspartate receptor activation -: Essential role of a TNF receptor 2-mediated phosphatidylinositol 3-kinase-dependent NF-κB pathway
L Marchetti et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
The neurobiology of glia in the context of water and ion homeostasis
M Simard et al.
NEUROSCIENCE (2004)
Water homeostasis in the brain: Basic concepts
HK Kimelberg
NEUROSCIENCE (2004)
Anchoring of aquaporin-4 in brain: Molecular mechanisms and implications for the physiology and pathophysiology of water transport
M Amiry-Moghaddam et al.
NEUROSCIENCE (2004)
Aminopyridazines inhibit β-amyloid-induced glial activation and neuronal damage in vivo
JM Craft et al.
NEUROBIOLOGY OF AGING (2004)
Alpha syntrophin deletion removes the perivascular but not the endothelial pool of aquaporin-4 at the blood-brain barrier and delays the development of brain edema in an experimental model of acute hyponatremia
M Amiry-Moghaddam et al.
FASEB JOURNAL (2004)
Absence of glial fibrillary acidic protein and vimentin prevents hypertrophy of astrocytic processes and improves post-traumatic regeneration
U Wilhelmsson et al.
JOURNAL OF NEUROSCIENCE (2004)
Distinct types of astroglial cells in the hippocampus differ in gap junction coupling
A Wallraff et al.
GLIA (2004)
Two-photon imaging of capillary blood flow in olfactory bulb glomeruli
E Chaigneau et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Inactivation of TNF signaling by rationally designed dominant-negative TNF variants
PM Steed et al.
SCIENCE (2003)
Transcriptional regulation by calcium, calcineurin, and NFAT
PG Hogan et al.
GENES & DEVELOPMENT (2003)
Lactate:: A preferred fuel for human brain metabolism in vivo
D Smith et al.
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM (2003)
Why is carbon from some polyunsaturates extensively recycled into lipid synthesis?
SC Cunnane et al.
LIPIDS (2003)
An α-syntrophin-dependent pool of AQP4 in astroglial end-feet confers bidirectional water flow between blood and brain
M Amiry-Moghaddam et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Insights into glutamate transport regulation in human astrocytes: Cloning of the promoter for excitatory amino acid transporter 2 (EAAT2)
ZZ Su et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Alzheimer's disease and angiogenesis
AH Vagnucci et al.
LANCET (2003)
Alzheimer's disease is associated with a selective increase in α7 nicotinic acetylcholine receptor immunoreactivity in astrocytes
T Teaktong et al.
GLIA (2003)
Neuron-to-astrocyte signaling is central to the dynamic control of brain microcirculation
M Zonta et al.
NATURE NEUROSCIENCE (2003)
β-amyloid peptide activates α7 nicotinic acetylcholine receptors expressed in Xenopus oocytes
KT Dineley et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Noradrenergic depletion potentiates β-amyloid-induced cortical inflammation:: implications for Alzheimer's disease
MT Heneka et al.
JOURNAL OF NEUROSCIENCE (2002)
Control of synaptic strength by glial TNFα
EC Beattie et al.
SCIENCE (2002)
Homocysteine, silent brain infarcts, and white matter lesions: The Rotterdam scan study
SE Vermeer et al.
ANNALS OF NEUROLOGY (2002)
Thrombospondin-1 as an endogenous inhibitor of angiogenesis and tumor growth
J Lawler
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2002)
Prediction of cognitive decline in normal elderly subjects with 2-[18F]fluoro-2-deoxy-D-glucose/positron-emission tomography (FDG/PET)
MJ de Leon et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
Is there an astrocyte-neuron ketone body shuttle?
M Guzmán et al.
TRENDS IN ENDOCRINOLOGY AND METABOLISM (2001)
Sleep disturbances in patients with Alzheimer's disease - Epidemiology, pathophysiology and treatment
MV Vitiello et al.
CNS DRUGS (2001)
Aβ1-40-related reduction in functional hyperemia in mouse neocortex during somatosensory activation
K Niwa et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
Cerebral metabolic and cognitive decline in persons at genetic risk for Alzheimer's disease
GW Small et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
β-amyloid1-42 binds to α7 nicotinic acetylcholine receptor with high affinity -: Implications for Alzheimer's disease pathology
HY Wang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)