4.5 Article

Comparative Effectiveness and Safety of Rivaroxaban and Warfarin Among Nonvalvular Atrial Fibrillation (NVAF) Patients with Obesity and Polypharmacy in the United States (US)

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Real-world effectiveness and safety of rivaroxaban versus warfarin among non-valvular atrial fibrillation patients with obesity in a US population

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Summary: This study demonstrated that rivaroxaban is an effective and safe treatment option for NVAF patients with obesity in a commercially-insured US population, with a 26% lower risk of stroke/SE compared to warfarin at 36 months post-treatment initiation. The risk of major bleeding was similar between rivaroxaban-initiated patients and warfarin-initiated patients.

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