Visible Light Mediated Synthesis of Oxindoles

Functionalized oxindoles are privileged heterocyclic scaffolds and common core structural motifs that are broadly present in numerous natural products and serve as key intermediates in the synthesis of biological products, agrochemicals, and pharmaceuticals. Oxindoles exhibit a broad pharmacological and physiological activities, and diverse range of applications in medicinal chemistry and biomedical research. Owing to these fascinating biological and physiological activities of oxindoles, several methodologies have been developed for the construction of oxindoles. In the past decade, the visible light mediated methodologies have attracted substantial attention and emerged as a promising approach for the construction of oxindoles. In this review, the visible light mediated synthesis of oxindoles have been described.

Automated summary

Functionalized oxindoles are important heterocyclic structures found in many natural products and are key intermediates in drug synthesis. Visible light mediated methodologies for the synthesis of oxindoles have received significant attention and show promise for future applications.