期刊
ADVANCED MATERIALS
卷 33, 期 37, 页码 -出版社
WILEY-V C H VERLAG GMBH
DOI: 10.1002/adma.202103953
关键词
Au-doped Ag; Te-2; bioimaging; cation exchange; NIR-IIb fluorescence; quantum dots
类别
资金
- National Natural Science Foundation of China [21934007, 22001262]
- Natural Science Foundation of Jiangsu Province [BK20200254]
- China Postdoctoral Science Foundation [2019M661966]
- Chinese Academy of Sciences [XDB32030200, 121E32KYSB20180021, ZDBS-LY-SLH021]
A novel NIR-IIb fluorescent probe of Au-doped Ag2Te quantum dots with high PLQY, stability, and biocompatibility was developed. Controllable Au dopant concentration in Ag2Te QDs allowed for wide range of PL emission in the NIR-IIb window and enhanced PL intensity, enabling successful in vivo monitoring of angiogenesis and arteriogenesis processes.
Fluorescence located in 1500-1700 nm (denoted as the near-infrared IIb window, NIR-IIb) has drawn great interest for bioimaging, owing to its ultrahigh tissue penetration depth and spatiotemporal resolution. Therefore, NIR-IIb fluorescent probes with high photoluminescence quantum yield (PLQY) and stability along with high biocompatibility are urgently pursued. Herein, a novel NIR-IIb fluorescent probe of Au-doped Ag2Te (Au:Ag2Te) quantum dots (QDs) is developed via a facile cation exchange method. The Au dopant concentration in the Ag2Te QDs is tunable from 0% to 10% by controlling the ratio of supplied Au precursor to Ag2Te QDs, resulting in a wide range of PL emission in the NIR-IIb window and a much-enhanced PL intensity. After surface modification, the Au:Ag2Te QDs possess bright NIR-IIb emission, high colloidal stability and photostability, and decent biocompatibility. Further, in vivo monitoring of the process of angiogenesis and arteriogenesis in an ischemic hindlimb is successfully performed.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据