Liposome composition in drug delivery design, synthesis, characterization, and clinical application

Liposomal drug delivery represents a highly adaptable therapeutic platform for treating a wide range of diseases. Natural and synthetic lipids, as well as surfactants, are commonly utilized in the synthesis of liposomal drug delivery vehicles. The molecular diversity in the composition of liposomes enables drug delivery with unique physiological functions, such as pH response, prolonged blood circulation, and reduced systemic toxicity. Herein, we discuss the impact of composition on liposome synthesis, function, and clinical utility. (c) 2021 Elsevier B.V. All rights reserved.

Automated summary

Liposomal drug delivery is a highly adaptable therapeutic platform for treating a wide range of diseases. The molecular diversity in liposome composition enables drug delivery with unique physiological functions, such as pH response and reduced systemic toxicity.