4.6 Article

Identification of a Novel Allosteric Site at the M5 Muscarinic Acetylcholine Receptor

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Pharmacology & Pharmacy

Muscarinic M4 and M5 receptors in the ventral subiculum differentially modulate alcohol seeking versus consumption in male alcohol-preferring rats

Leigh C. Walker et al.

Summary: Long-term alcohol consumption and abstinence cause dysregulation of muscarinic receptors gene expression in vSub, with M-4 and M-5 receptors playing distinct roles in regulating alcohol-seeking behavior.

BRITISH JOURNAL OF PHARMACOLOGY (2021)

Article Multidisciplinary Sciences

Structures of the M1 and M2 muscarinic acetylcholine receptor/G-protein complexes

Shoji Maeda et al.

SCIENCE (2019)

Article Biochemistry & Molecular Biology

Structure of an allosteric modulator bound to the CB1 cannabinoid receptor

Zhenhua Shao et al.

NATURE CHEMICAL BIOLOGY (2019)

Article Multidisciplinary Sciences

Crystal structure of the M5 muscarinic acetylcholine receptor

Ziva Vuckovic et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2019)

Article Chemistry, Medicinal

Comparative Evaluation of Covalent Docking Tools

Andrea Scarpino et al.

JOURNAL OF CHEMICAL INFORMATION AND MODELING (2018)

Article Biochemistry & Molecular Biology

Orthosteric and allosteric action of the C5a receptor antagonists

Heng Liu et al.

NATURE STRUCTURAL & MOLECULAR BIOLOGY (2018)

Article Neurosciences

Muscarinic M5 receptors modulate ethanol seeking in rats

Alice E. Berizzi et al.

NEUROPSYCHOPHARMACOLOGY (2018)

Article Biochemistry & Molecular Biology

Orthosteric and allosteric action of the C5a receptor antagonists

Heng Liu et al.

NATURE STRUCTURAL & MOLECULAR BIOLOGY (2018)

Review Multidisciplinary Sciences

Structural insights into G-protein-coupled receptor allostery

David M. Thal et al.

NATURE (2018)

Article Biochemistry & Molecular Biology

Selective inhibition of M5 muscarinic acetylcholine receptors attenuates cocaine self-administration in rats

Barak W. Gunter et al.

ADDICTION BIOLOGY (2018)

Article Biochemistry & Molecular Biology

Structural basis for the cooperative allosteric activation of the free fatty acid receptor GPR40

Jun Lu et al.

NATURE STRUCTURAL & MOLECULAR BIOLOGY (2017)

Review Pharmacology & Pharmacy

Applying Structure-Based Drug Design Approaches to Allosteric Modulators of GPCRs

Miles Congreve et al.

TRENDS IN PHARMACOLOGICAL SCIENCES (2017)

Article Biochemistry & Molecular Biology

Structural basis for the cooperative allosteric activation of the free fatty acid receptor GPR40

Jun Lu et al.

NATURE STRUCTURAL & MOLECULAR BIOLOGY (2017)

Article Multidisciplinary Sciences

Extra-helical binding site of a glucagon receptor antagonist

Ali Jazayeri et al.

NATURE (2016)

Article Multidisciplinary Sciences

Crystal structures of the M1 and M4 muscarinic acetylcholine receptors

David M. Thal et al.

NATURE (2016)

Article Pharmacology & Pharmacy

Molecular Mechanisms of Action of M5 Muscarinic Acetylcholine Receptor Allosteric Modulators

Alice E. Berizzi et al.

MOLECULAR PHARMACOLOGY (2016)

Article Chemistry, Medicinal

Further optimization of the M5 NAM MLPCN probe ML375: Tactics and challenges

Haruto Kurata et al.

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2015)

Article Biochemistry & Molecular Biology

Molecular Mechanisms of Bitopic Ligand Engagement with the M1 Muscarinic Acetylcholine Receptor

Peter Keov et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2014)

Article Biochemistry & Molecular Biology

Molecular Determinants of Allosteric Modulation at the M1 Muscarinic Acetylcholine Receptor

Alaa Abdul-Ridha et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2014)

Review Biotechnology & Applied Microbiology

Muscarinic acetylcholine receptors: novel opportunities for drug development

Andrew C. Kruse et al.

NATURE REVIEWS DRUG DISCOVERY (2014)

Article Biochemistry & Molecular Biology

Modified T4 Lysozyme Fusion Proteins Facilitate G Protein-Coupled Receptor Crystallogenesis

Thor Seneca Thorsen et al.

STRUCTURE (2014)

Article Multidisciplinary Sciences

Structural basis for modulation of a G-protein-coupled receptor by allosteric drugs

Ron O. Dror et al.

NATURE (2013)

Article Multidisciplinary Sciences

Activation and allosteric modulation of a muscarinic acetylcholine receptor

Andrew C. Kruse et al.

NATURE (2013)

Article Pharmacology & Pharmacy

Novel Allosteric Effects of Amiodarone at the Muscarinic M5 Receptor

Edward Stahl et al.

JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2010)

Article Multidisciplinary Sciences

Selective activation of the M1 muscarinic acetylcholine receptor achieved by allosteric potentiation

Lei Ma et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)

Article Biochemistry & Molecular Biology

A new method for ligand docking to flexible receptors by dual alanine scanning and refinement (SCARE)

Giovanni Bottegoni et al.

JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN (2008)

Review Pharmacology & Pharmacy

Muscarinic acetylcholine receptors as CNS drug targets

Christopher J. Langmead et al.

PHARMACOLOGY & THERAPEUTICS (2008)

Review Neurosciences

Allosteric modulation of muscarinic acetylcholine receptors

Karen J. Gregory et al.

CURRENT NEUROPHARMACOLOGY (2007)

Article Pharmacology & Pharmacy

Allosteric binding sites on muscarinic acetylcholine receptors

J Wess

MOLECULAR PHARMACOLOGY (2005)

Article Biochemical Research Methods

Pocketome via comprehensive identification and classification of ligand binding envelopes

JH An et al.

MOLECULAR & CELLULAR PROTEOMICS (2005)

Article Neurosciences

Role for M5 muscarinic acetylcholine receptors in cocaine addiction

A Fink-Jensen et al.

JOURNAL OF NEUROSCIENCE RESEARCH (2003)

Article Pharmacology & Pharmacy

Analogs of WIN 62,577 define a second allosteric site on muscarinic receptors

S Lazareno et al.

MOLECULAR PHARMACOLOGY (2002)

Article Multidisciplinary Sciences

Deletion of the M5 muscarinic acetylcholine receptor attenuates morphine reinforcement and withdrawal but not morphine analgesia

AS Basile et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)

Review Pharmacology & Pharmacy

G protein-coupled receptor allosterism and complexing

A Christopoulos et al.

PHARMACOLOGICAL REVIEWS (2002)