相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Structural Basis of Human KCNQ1 Modulation and Gating
Ji Sun et al.
CELL (2020)
A structural overview of the ion channels of the TRPM family
Yihe Huang et al.
CELL CALCIUM (2020)
Selective profiling of N- and C-terminal nucleotide-binding sites in a TRPM2 channel
Balazs Toth et al.
JOURNAL OF GENERAL PHYSIOLOGY (2020)
Structure-Function Relationship of TRPM2: Recent Advances, Contradictions, and Open Questions
Frank J. P. Kuehn
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)
Global alignment and assessment of TRP channel transmembrane domain structures to explore functional mechanisms
Katherine E. Huffer et al.
ELIFE (2020)
Structural basis of cooling agent and lipid sensing by the cold-activated TRPM8 channel
Ying Yin et al.
SCIENCE (2019)
Enzyme activity and selectivity filter stability of ancient TRPM2 channels were simultaneously lost in early vertebrates
Iordan Iordanov et al.
ELIFE (2019)
Symmetry transitions during gating of the TRPV2 ion channel in lipid membranes
Lejla Zubcevic et al.
ELIFE (2019)
Direct Gating of the TRPM2 Channel by cADPR via Specific Interactions with the ADPR Binding Pocket
Peilin Yu et al.
CELL REPORTS (2019)
Ligand recognition and gating mechanism through three ligand-binding sites of human TRPM2 channel
Yihe Huang et al.
ELIFE (2019)
Visualizing structural transitions of ligand-dependent gating of the TRPM2 channel
Ying Yin et al.
NATURE COMMUNICATIONS (2019)
STRUCTURE, GATING, AND REGULATION OF THE CFTR ANION CHANNEL
Laszlo Csanady et al.
PHYSIOLOGICAL REVIEWS (2019)
Different substrate specificities of the two ADPR binding sites in TRPM2 channels of Nematostella vectensis and the role of IDPR
Frank J. P. Kuehn et al.
SCIENTIFIC REPORTS (2019)
Structure of the human TRPM4 ion channel in a lipid nanodisc
Henriette E. Autzen et al.
SCIENCE (2018)
From Electron Crystallography to Single Particle CryoEM (Nobel Lecture)
R. Henderson
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2018)
Cryo-EM structure of a mitochondrial calcium uniporter
Jiho Yoo et al.
SCIENCE (2018)
Structure of a TRPM2 channel in complex with Ca2+ explains unique gating regulation
Zhe Zhang et al.
ELIFE (2018)
X-ray and cryo-EM structures of the mitochondrial calcium uniporter
Chao Fan et al.
NATURE (2018)
Cryo-EM structure of a fungal mitochondrial calcium uniporter
Nam X. Nguyen et al.
NATURE (2018)
Cryo-EM structures of fungal and metazoan mitochondrial calcium uniporters
Rozbeh Baradaran et al.
NATURE (2018)
Architecture of the TRPM2 channel and its activation mechanism by ADP-ribose and calcium
Yihe Huang et al.
NATURE (2018)
Structure of the mouse TRPC4 ion channel
Jingjing Duan et al.
NATURE COMMUNICATIONS (2018)
Structures and gating mechanism of human TRPM2
Longfei Wang et al.
SCIENCE (2018)
Conformational ensemble of the human TRPV3 ion channel
Lejla Zubcevic et al.
NATURE COMMUNICATIONS (2018)
Structural insights on TRPV5 gating by endogenous modulators
Taylor E. T. Hughes et al.
NATURE COMMUNICATIONS (2018)
Electron cryo-microscopy structure of the mechanotransduction channel NOMPC
Peng Jin et al.
NATURE (2017)
Structures of the calcium-activated, non-selective cation channel TRPM4
Jiangtao Guo et al.
NATURE (2017)
Electron cryo-microscopy structure of a human TRPM4 channel
Paige A. Winkler et al.
NATURE (2017)
2′-Deoxyadenosine 5′-diphosphoribose is an endogenous TRPM2 superagonist
Ralf Fliegert et al.
NATURE CHEMICAL BIOLOGY (2017)
Cryo-EM Structures of the Magnesium Channel CorA Reveal Symmetry Break upon Gating
Doreen Matthies et al.
CELL (2016)
TRPV1 structures in nanodiscs reveal mechanisms of ligand and lipid action
Yuan Gao et al.
NATURE (2016)
The TRPM2 channel is a hypothalamic heat sensor that limits fever and can drive hypothermia
Kun Song et al.
SCIENCE (2016)
The proposed channel-enzyme transient receptor potential melastatin 2 does not possess ADP ribose hydrolase activity
Iordan Iordanov et al.
ELIFE (2016)
ADP-Ribose Activates the TRPM2 Channel from the Sea Anemone Nematostella vectensis Independently of the NUDT9H Domain
Frank J. P. Kuehn et al.
PLOS ONE (2016)
Ruling out pyridine dinucleotides as true TRPM2 channel activators reveals novel direct agonist ADP-ribose-2′-phosphate
Balazs Toth et al.
JOURNAL OF GENERAL PHYSIOLOGY (2015)
Structure of the TRPA1 ion channel suggests regulatory mechanisms
Candice E. Paulsen et al.
NATURE (2015)
The EMBL-EBI bioinformatics web and programmatic tools framework
Weizhong Li et al.
NUCLEIC ACIDS RESEARCH (2015)
The TRPM7 Chanzyme Is Cleaved to Release a Chromatin-Modifying Kinase
Grigory Krapivinsky et al.
CELL (2014)
Putative chanzyme activity of TRPM2 cation channel is unrelated to pore gating
Balazs Toth et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
Structure-Activity Relationship of Adenosine 5′-diphosphoribose at the Transient Receptor Potential Melastatin 2 (TRPM2) Channel: Rational Design of Antagonists
Christelle Moreau et al.
JOURNAL OF MEDICINAL CHEMISTRY (2013)
Structure of the TRPV1 ion channel determined by electron cryo-microscopy
Maofu Liao et al.
NATURE (2013)
Pore collapse underlies irreversible inactivation of TRPM2 cation channel currents
Balazs Toth et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Transient Receptor Potential Melastatin 1 (TRPM1) Is an Ion-conducting Plasma Membrane Channel Inhibited by Zinc Ions
Sachar Lambert et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Decrease in phosphatidylinositol 4,5-bisphosphate levels mediates desensitization of the cold sensor TRPM8 channels
Yevgen Yudin et al.
JOURNAL OF PHYSIOLOGY-LONDON (2011)
Function and metabolism of sirtuin metabolite O-acetyl-ADP-ribose
Lei Tong et al.
BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS (2010)
Identification of Direct and Indirect Effectors of the Transient Receptor Potential Melastatin 2 (TRPM2) Cation Channel
Balazs Toth et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Strict coupling between CFTR's catalytic cycle and gating of its Cl- ion pore revealed by distributions of open channel burst durations
Laszlo Csanady et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Jalview Version 2-a multiple sequence alignment editor and analysis workbench
Andrew M. Waterhouse et al.
BIOINFORMATICS (2009)
Four Ca2+ Ions Activate TRPM2 Channels by Binding in Deep Crevices near the Pore but Intracellularly of the Gate
Laszlo Csanady et al.
JOURNAL OF GENERAL PHYSIOLOGY (2009)
Synergistic regulation of endogenous TRPM2 channels by adenine dinucleotides in primary human neutrophils
Ingo Lange et al.
CELL CALCIUM (2008)
Identification of pore residues engaged in determining divalent cationic permeation in transient receptor potential melastatin subtype channel
Rong Xia et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
TRPM2-mediated Ca2+ influx induces chemokine production in monocytes that aggravates inflammatory neutrophil infiltration
Shinichiro Yamamoto et al.
NATURE MEDICINE (2008)
Altered functional properties of a TRPM2 variant in Guamanian ALS and PD
Meredith C. Hermosura et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Regulation of TRPM2 by extra- and intracellular calcium
John Starkus et al.
JOURNAL OF GENERAL PHYSIOLOGY (2007)
Regulation of transient receptor potential (TRP) channels by phosphoinositides
Tibor Rohacs et al.
PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY (2007)
Transient receptor potential cation channels in disease
Bernd Nilius et al.
PHYSIOLOGICAL REVIEWS (2007)
Conserved cysteine residues in the pore region are obligatory for human TRPM2 channel function
Zhu-Zhong Mei et al.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2006)
Endogenous ADP-ribose enables calcium-regulated cation currents through TRPM2 channels in neutrophil granulocytes
Inka Heiner et al.
BIOCHEMICAL JOURNAL (2006)
Metabolite of SIR2 reaction modulates TRPM2 ion channel
Olivera Grubisha et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Nicotinic acid adenine dinucleotide phosphate and cyclic ADP-ribose regulate TRPM2 channels in T lymphocytes
Andreas Beck et al.
FASEB JOURNAL (2006)
Regulation of the transient receptor potential channel TRPM2 by the Ca2+ sensor calmodulin
Q Tong et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Amyloid β-peptide(1-42) and hydrogen peroxide-induced toxicity are mediated by TRPM2 in rat primary striatal cultures
E Fonfria et al.
JOURNAL OF NEUROCHEMISTRY (2005)
Crystal structure of a mammalian voltage-dependent Shaker family K+ channel
SB Long et al.
SCIENCE (2005)
Voltage sensor of kv1.2: Structural basis of electromechanical coupling
SB Long et al.
SCIENCE (2005)
Cyclic ADP-ribose and hydrogen peroxide synergize with ADP-ribose in the activation of TRPM2 channels
M Kolisek et al.
MOLECULAR CELL (2005)
Accumulation of free ADP-ribose from mitochondria mediates oxidative stress-induced gating of TRPM2 cation channels
AL Perraud et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Structures and mechanisms of Nudix hydrolases
AS Mildvan et al.
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2005)
TRPM6 forms the Mg2+ influx channel involved in intestinal and renal Mg2+ absorption
T Voets et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Sites of the NUDT9-H domain critical for ADP-ribose activation of the cation channel TRPM2
FJP Kühn et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Intracellular Call and the phospholipid PIP2 regulate the taste transduction ion channel TRPM5
D Liu et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
The crystal structure and mutational analysis of human NUDT9
BW Shen et al.
JOURNAL OF MOLECULAR BIOLOGY (2003)
Molecular and functional characterization of the melastatin-related cation channel TRPM3
C Grimm et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Critical intracellular Ca2+ dependence of transient receptor potential melastatin 2 (TRPM2) cation channel activation
D McHugh et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
NUDT9, a member of the nudix hydrolase family, is an evolutionarily conserved mitochondrial ADP-ribose pyrophosphatase
AL Perraud et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Analysis of O-acetyl-ADP-ribose as a target for Nudix ADP-ribose hydrolases
LA Rafty et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Mutational, kinetic, and NMR studies of the mechanism of E. coli GDP-mannose mannosyl hydrolase, an unusual nudix enzyme
PM Legler et al.
BIOCHEMISTRY (2002)
Mechanism of the Escherichia coli ADP-ribose pyrophosphatase, a nudix hydrolase
SB Gabelli et al.
BIOCHEMISTRY (2002)
TRPM4 is a Ca2+-activated nonselective cation channel mediating cell membrane depolarization
P Launay et al.
CELL (2002)
Chemistry of ion coordination and hydration revealed by a K+ channel-Fab complex at 2.0 Å resolution
YF Zhou et al.
NATURE (2001)
Immunocyte Ca2+ influx system mediated by LTRPC2
Y Sano et al.
SCIENCE (2001)
ADP-ribose gating of the calcium-permeable LTRPC2 channel revealed by Nudix motif homology
AL Perraud et al.
NATURE (2001)
Mutational, kinetic, and NMR studies of the roles of conserved glutamate residues and of lysine-39 in the mechanism of the MutT pyrophosphohydrolase
TK Harris et al.
BIOCHEMISTRY (2000)