4.6 Article

Gut Microbiota Influence Lipid Metabolism of Skeletal Muscle in Pigs

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Review Endocrinology & Metabolism

Butyrate in Energy Metabolism: There Is Still More to Learn

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Summary: Butyrate, as a main product of gut microbial fermentation, plays an important role in regulating whole body energy homeostasis. Research has shown that butyrate has multiple effects on metabolic health, including thermogenesis, lipid and glucose metabolism, appetite, inflammation, and influence on gut microbiota. Through pathways such as G protein-coupled receptors (GPRs) and acting as a histone deacetylase inhibitor, butyrate also impacts cellular systems.

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