4.6 Article

Low Vitamin D Level in Saudi Women With Polycystic Ovary Syndrome

期刊

FRONTIERS IN NUTRITION
卷 8, 期 -, 页码 -

出版社

FRONTIERS MEDIA SA
DOI: 10.3389/fnut.2021.611351

关键词

BMI; females; polycystic ovary syndrome; vitamin D; 25-dihydroxyvitamin D

资金

  1. Research Center of the Female Scientific and Medical Colleges, Deanship of Scientific Research, King Saud University

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The study showed that women with PCOS have lower vitamin D levels and a higher obesity rate compared to controls. Fewer patients with PCOS consumed milk and dairy products, and were exposed to sunlight, than controls.
Polycystic ovary syndrome (PCOS) is a common endocrine disorder in women of reproductive age. In this study, serum 25-hydroxyvitamin D levels were compared between women with and without PCOS and with regard to anthropometric indices and lipid and glucose biomarkers. Thirty-one women with PCOS and 75 controls answered a questionnaire on vitamin D, in addition to general health and lifestyle. The patients with PCOS had lower vitamin D levels (p < 0.05), a significantly higher rate of obesity (p < 0.05), and significantly higher serum triglyceride levels than did controls. The number of patients with PCOS consumed milk and dairy products (p < 0.05) and exposed to sun (p < 0.006) were lower compared to controls. Triglyceride levels were significantly correlated with body mass index (BMI); vitamin D level was not significantly correlated with anthropometrical or biochemical variables. These results affirm that vitamin D levels are lower in women with PCOS; however, despite the significantly higher proportion of obesity among patients with PCOS, hypovitaminosis was not associated with BMI. The relationship between body composition and vitamin D in PCOS and the effect of vitamin D correction on metabolic and hormonal parameters associated with PCOS must be assessed in future trials.

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