4.7 Article

Nutrient infusion in the dorsal vagal complex controls hepatic lipid and glucose metabolism in rats

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Endocrinology & Metabolism

Inhibition of mitochondrial fission and iNOS in the dorsal vagal complex protects from overeating and weight gain

Bianca Patel et al.

Summary: The study revealed that activation of Drp1 in the DVC increases weight gain in rats, while inhibition of Drp1 in HFD-fed rats reduces food intake, weight gain, and adipose tissue. Rats with higher levels of iNOS in the DVC had decreased food intake, weight gain, and adipose tissue when iNOS was knocked down. Inhibiting mitochondrial fission in DVC astrocytes protected rats from HFD-induced insulin resistance, hyperphagia, weight gain, and fat deposition.

MOLECULAR METABOLISM (2021)

Review Endocrinology & Metabolism

Hypothalamic glucose-sensing mechanisms

Nal Ae Yoon et al.

Summary: This article reviews the current literature on hypothalamic glucose-sensing mechanisms and discusses the impact of alterations of these mechanisms on the pathogenesis of diabetes.

DIABETOLOGIA (2021)

Article Endocrinology & Metabolism

Central Sfrp5 regulates hepatic glucose flux and VLDL-triglyceride secretion

Yang Li et al.

METABOLISM-CLINICAL AND EXPERIMENTAL (2020)

Article Endocrinology & Metabolism

Central KATP Channels Modulate Glucose Effectiveness in Humans and Rodents

Michelle Carey et al.

DIABETES (2020)

Article Medicine, Research & Experimental

Type 2 diabetes risk gene Dusp8 regulates hypothalamic Jnk signaling and insulin sensitivity

Sonja C. Schriever et al.

JOURNAL OF CLINICAL INVESTIGATION (2020)

Article Multidisciplinary Sciences

Brain leptin reduces liver lipids by increasing hepatic triglyceride secretion and lowering lipogenesis

Martina Theresa Hackl et al.

NATURE COMMUNICATIONS (2019)

Article Endocrinology & Metabolism

Peripheral Mechanisms Mediating the Sustained Antidiabetic Action of FGF1 in the Brain

Jarrad M. Scarlett et al.

DIABETES (2019)

Article Biochemistry & Molecular Biology

Leptin enhances hypothalamic lactate dehydrogenase A (LDHA)-dependent glucose sensing to lower glucose production in high-fat-fed rats

Mona A. Abraham et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2018)

Review Gastroenterology & Hepatology

The metabolic role of vagal afferent innervation

T. M. Zaved Waise et al.

NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY (2018)

Article Biochemistry & Molecular Biology

Gut microbiota and intestinal FXR mediate the clinical benefits of metformin

Lulu Sun et al.

NATURE MEDICINE (2018)

Review Biochemistry & Molecular Biology

Central nervous system regulation of hepatic lipid and lipoprotein metabolism

Jennifer Taher et al.

CURRENT OPINION IN LIPIDOLOGY (2017)

Review Cardiac & Cardiovascular Systems

Metabolic Syndrome: Clinical and Policy Implications of the New Silent Killer

Dawn Harris Sherling et al.

JOURNAL OF CARDIOVASCULAR PHARMACOLOGY AND THERAPEUTICS (2017)

Article Endocrinology & Metabolism

Acute activation of GLP-1-expressing neurons promotes glucose homeostasis and insulin sensitivity

Xuemei Shi et al.

MOLECULAR METABOLISM (2017)

Article Physiology

High glucose increases action potential firing of catecholamine neurons in the nucleus of the solitary tract by increasing spontaneous glutamate inputs

Brandon L. Roberts et al.

AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY (2017)

Article Neurosciences

Glucose sensing by GABAergic neurons in the mouse nucleus tractus solitarii

Carie R. Boychuk et al.

JOURNAL OF NEUROPHYSIOLOGY (2015)

Article Biochemistry & Molecular Biology

Resveratrol activates duodenal Sirt1 to reverse insulin resistance in rats through a neuronal network

Clemence D. Cote et al.

NATURE MEDICINE (2015)

Article Multidisciplinary Sciences

Intestine-selective farnesoid X receptor inhibition improves obesity-related metabolic dysfunction

Changtao Jiang et al.

NATURE COMMUNICATIONS (2015)

Article Physiology

Hindbrain lactostasis regulates hypothalamic AMPK activity and metabolic neurotransmitter mRNA and protein responses to hypoglycemia

Amit D. Gujar et al.

AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY (2014)

Article Physiology

Stimulation of feeding by three different glucose-sensing mechanisms requires hindbrain catecholamine neurons

Ai-Jun Li et al.

AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY (2014)

Article Endocrinology & Metabolism

Insulin Signals Through the Dorsal Vagal Complex to Regulate Energy Balance

Beatrice M. Filippi et al.

DIABETES (2014)

Article Endocrinology & Metabolism

GLP-1 receptor agonism ameliorates hepatic VLDL overproduction and de novo lipogenesis in insulin resistance

Jennifer Taher et al.

MOLECULAR METABOLISM (2014)

Article Cell Biology

Regional distribution of SGLT activity in rat brain in vivo

Amy S. Yu et al.

AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2013)

Article Medicine, Research & Experimental

FGF19 action in the brain induces insulin-independent glucose lowering

Gregory J. Morton et al.

JOURNAL OF CLINICAL INVESTIGATION (2013)

Review Multidisciplinary Sciences

Cooperation between brain and islet in glucose homeostasis and diabetes

Michael W. Schwartz et al.

NATURE (2013)

Review Neurosciences

Wired on sugar: the role of the CNS in the regulation of glucose homeostasis

Bernadette E. Grayson et al.

NATURE REVIEWS NEUROSCIENCE (2013)

Article Endocrinology & Metabolism

Endogenous leptin receptor signaling in the medial nucleus tractus solitarius affects meal size and potentiates intestinal satiation signals

Scott E. Kanoski et al.

AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2012)

Review Cell Biology

Lipid Sensing and Insulin Resistance in the Brain

Jessica T. Y. Yue et al.

CELL METABOLISM (2012)

Article Cell Biology

Brainstem Nutrient Sensing in the Nucleus of the Solitary Tract Inhibits Feeding

Clemence Blouet et al.

CELL METABOLISM (2012)

Article Cardiac & Cardiovascular Systems

Glycine Normalizes Hepatic Triglyceride-Rich VLDL Secretion by Triggering the CNS in High-Fat Fed Rats

Jessica T. Y. Yue et al.

CIRCULATION RESEARCH (2012)

Article Endocrinology & Metabolism

Hypothalamic Leucine Metabolism Regulates Liver Glucose Production

Ya Su et al.

DIABETES (2012)

Article Biochemistry & Molecular Biology

Short Term Voluntary Overfeeding Disrupts Brain Insulin Control of Adipose Tissue Lipolysis

Thomas Scherer et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2012)

Article Medicine, Research & Experimental

Obesity is associated with hypothalamic injury in rodents and humans

Joshua P. Thaler et al.

JOURNAL OF CLINICAL INVESTIGATION (2012)

Article Medicine, Research & Experimental

Activation of KATP channels suppresses glucose production in humans

Preeti Kishore et al.

JOURNAL OF CLINICAL INVESTIGATION (2011)

Review Physiology

Leptin and the Central Nervous System Control of Glucose Metabolism

Gregory J. Morton et al.

PHYSIOLOGICAL REVIEWS (2011)

Article Endocrinology & Metabolism

Hypothalamic AMP-Activated Protein Kinase Regulates Glucose Production

Clair S. Yang et al.

DIABETES (2010)

Article Biochemistry & Molecular Biology

Activation of N-Methyl-D-aspartate (NMDA) Receptors in the Dorsal Vagal Complex Lowers Glucose Production

Carol K. L. Lam et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2010)

Article Endocrinology & Metabolism

Regulation of lipid metabolism by energy availability: a role for the central nervous system

R. Nogueiras et al.

OBESITY REVIEWS (2010)

Article Endocrinology & Metabolism

Activation of sodium-glucose cotransporter 1 ameliorates hyperglycemia by mediating incretin secretion in mice

Ryuichi Moriya et al.

AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2009)

Article Cell Biology

Intestinal Cholecystokinin Controls Glucose Production through a Neuronal Network

Grace W. C. Cheung et al.

CELL METABOLISM (2009)

Article Endocrinology & Metabolism

Effects of Exercise Training on Hepatic Microsomal Triglyceride Transfer Protein Content in Rats

N. A. Chapados et al.

HORMONE AND METABOLIC RESEARCH (2009)

Article Neurosciences

Dissociation between sensing and metabolism of glucose in sugar sensing neurones

J. Antonio Gonzalez et al.

JOURNAL OF PHYSIOLOGY-LONDON (2009)

Article Neurosciences

Impact of short-term high-fat feeding on glucose and insulin metabolism in young healthy men

Charlotte Brons et al.

JOURNAL OF PHYSIOLOGY-LONDON (2009)

Article Gastroenterology & Hepatology

D-Glucose modulates synaptic transmission from the central terminals of vagal afferent fibers

Shuxia Wan et al.

AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2008)

Article Endocrinology & Metabolism

Central nervous system neuropeptide Y signaling modulates VLDL triglyceride secretion

John M. Stafford et al.

DIABETES (2008)

Article Endocrinology & Metabolism

Arcuate glucagon-like peptide 1 receptors regulate glucose homeostasis but not food intake

Darleen A. Sandoval et al.

DIABETES (2008)

Article Multidisciplinary Sciences

Upper intestinal lipids trigger a gut-brain-liver axis to regulate glucose production

Penny Y. T. Wang et al.

NATURE (2008)

Article Biochemistry & Molecular Biology

Leptin controls adipose tissue lipogenesis via central, STAT3-independent mechanisms

Christoph Buettner et al.

NATURE MEDICINE (2008)

Article Medicine, Research & Experimental

The central melanocortin system directly controls peripheral lipid metabolism

Ruben Nogueiras et al.

JOURNAL OF CLINICAL INVESTIGATION (2007)

Article Multidisciplinary Sciences

Glucose sensing by POMC neurons regulates glucose homeostasis and is impaired in obesity

Laura E. Parton et al.

NATURE (2007)

Article Physiology

Localized glucoprivation of hindbrain sites elicits corticosterone and glucagon secretion

Shayne F. Andrew et al.

AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY (2007)

Article Biochemistry & Molecular Biology

Brain glucose metabolism controls the hepatic secretion of triglyceride-rich lipoproteins

Tony K. T. Lam et al.

NATURE MEDICINE (2007)

Article Endocrinology & Metabolism

Sodium-coupled glucose cotransporters contribute to hypothalamic glucose sensing

Dervla O'Malley et al.

DIABETES (2006)

Article Endocrinology & Metabolism

The effects of short-term overfeeding on insulin action in lean and reduced-obese individuals

Marc-Andre Cornier et al.

METABOLISM-CLINICAL AND EXPERIMENTAL (2006)

Article Medicine, Research & Experimental

Ghrelin action in the brain controls adipocyte metabolism

Claudia Theander-Carrillo et al.

JOURNAL OF CLINICAL INVESTIGATION (2006)

Article Medicine, Research & Experimental

Restoration of hypothalamic lipid sensing normalizes energy and glucose homeostasis in overfed rats

A Pocai et al.

JOURNAL OF CLINICAL INVESTIGATION (2006)

Article Neurosciences

Neuronal responses to transient hypoglycaemia in the dorsal vagal complex of the rat brainstem

RH Balfour et al.

JOURNAL OF PHYSIOLOGY-LONDON (2006)

Article Physiology

Lactate is a critical sensed variable in caudal hindbrain monitoring of CNS metabolic stasis

GD Patil et al.

AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY (2005)

Article Multidisciplinary Sciences

Regulation of blood glucose by hypothalamic pyruvate metabolism

TKT Lam et al.

SCIENCE (2005)

Article Multidisciplinary Sciences

Hypothalamic KATP channels control hepatic glucose production

A Pocai et al.

NATURE (2005)

Article Biochemistry & Molecular Biology

Hypothalamic sensing of circulating fatty acids is required for glucose homeostasis

TKT Lam et al.

NATURE MEDICINE (2005)

Article Biochemistry & Molecular Biology

Free fatty acids regulate gut incretin glucagon-like peptide-1 secretion through GPR120

A Hirasawa et al.

NATURE MEDICINE (2005)

Article Endocrinology & Metabolism

Free fatty acids increase basal hepatic glucose production and induce hepatic insulin resistance at different sites

TKT Lam et al.

AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2003)

Article Endocrinology & Metabolism

Central administration of oleic acid inhibits glucose production and food intake

S Obici et al.

DIABETES (2002)

Article Endocrinology & Metabolism

Overfeeding rapidly induces leptin and insulin resistance

JL Wang et al.

DIABETES (2001)

Article Psychology, Biological

Effects of lactate on glucose-sensing neurons in the solitary tract nucleus

T Himmi et al.

PHYSIOLOGY & BEHAVIOR (2001)