期刊
EUROPEAN RADIOLOGY
卷 27, 期 7, 页码 2934-2940出版社
SPRINGER
DOI: 10.1007/s00330-016-4610-1
关键词
Laser; Thermal ablation; Minimally invasive treatment; Papillary thyroid microcarcinoma; Ultrasound
资金
- national clinical key specialty construction projects of China
- Science and Technology Commission Foundation of Shanghai
To evaluate the efficacy and safety of percutaneous laser ablation (PLA) for unifocal T1N0M0 papillary thyroid microcarcinoma(PTMC). A retrospective study was conducted in 30 patients with single PTMC which was diagnosed by fine-needle aspiration biopsy (FNAB). PLA was performed for proper time to achieve adequate ablation zones. The extent of ablation was assessed by contrast-enhanced ultrasound (CEUS) immediately and 7 days after PLA. Complications were recorded. The size and volume of the ablation area and thyroid hormones were measured, and clinical evaluations were performed at 1, 3, 6 and12 months, and every half year thereafter. The procedure was well tolerated without serious complications. Of the 30 patients, 29 were treated successfully under local anaesthesia in a single session. Only one incomplete ablation was detected by immediate CEUS after PLA, and a second ablation was performed. At the last follow-up, ten (33.3 %) ablation zones had disappeared, and 20 (66.67 %) ablation zones remained as scar-like lesions. No regrowth of treated tumours, local recurrence or distant metastases were detected. During the short-term follow-up period, ultrasound-guided PLA appears to be effective and safe for treating solitary T1N0M0 PTMC in selected patients who are ineligible for surgery. aEuro cent Ultrasound is a useful tool in percutaneous laser ablation (PLA). aEuro cent PLA is safe for treating papillary thyroid microcarcinoma. aEuro cent PLA is effective for single papillary thyroid microcarcinoma.
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