期刊
FRONTIERS IN VETERINARY SCIENCE
卷 8, 期 -, 页码 -出版社
FRONTIERS MEDIA SA
DOI: 10.3389/fvets.2021.659051
关键词
Escherichia coli; antimicrobial resistance; antimicrobial use; pig; intensive production
资金
- Swiss National Science Foundation: [Eccellenza Grant]
- Swiss National Science Foundation: [National Research Program 72 Antimicrobial Resistance] [40AR40_180179]
- Joint Programming initiative on Antimicrobial resistance (JPIAMR)
- Branco Weiss Foundation
- Swiss National Science Foundation
- Swiss National Science Foundation (SNF) [40AR40_180179] Funding Source: Swiss National Science Foundation (SNF)
In Thailand, pig production has increased significantly in recent decades to meet growing demand for pork, but the use of antimicrobials has also led to an increase in antimicrobial resistance. The study found that farms using antibiotics had a higher proportion of antimicrobial-resistant E. coli, and medium-scale farms with intensive animal production practices showed higher resistance rates. Farms located closer to drugstores and with a higher disease proportion had drug-resistant Escherichia coli.
In Thailand, pig production has increased considerably in the last decades to meet a growing demand for pork. Antimicrobials are used routinely in intensive pig production to treat infections and increase productivity. However, the use of antimicrobials also contributes to the rise of antimicrobial resistance with potential consequences for animal and human health. Here, we quantify the association between antimicrobial use and resistance rates in extensive and intensive farms with a focus on geographic proximity between farm and drugstores. Of the 164 enrolled farms, 79% reported using antimicrobials for disease prevention, treatment, or as a feed additive. Antimicrobial-resistant E. coli were present in 63% of farms. These drugs included critically important antimicrobials, such as quinolones and penicillins. Medium-scale farms with intensive animal production practices showed higher resistance rates than small-scale farms with extensive practices. Farms with drug-resistant Escherichia coli were located closer to drugstores and a had a higher proportion of disease than farms without drug-resistant E. coli. We found no association between the presence of resistance in humans and antimicrobial use in pigs. Our findings call for actions to improve herd health to reduce the need for antimicrobials and systematic training of veterinarians and drugstore owners on judicious use of antimicrobials in animals to mitigate resistance.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据